KIF1C

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KIF1C
Protein KIF1C PDB 2g1l.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases KIF1C, LTXS1, SATX2, SAX2, SPAX2, SPG58, kinesin family member 1C
External IDs MGI: 1098260 HomoloGene: 4821 GeneCards: KIF1C
RNA expression pattern
PBB GE KIF1C 209244 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006612

NM_153103

RefSeq (protein)

NP_006603

NP_694743.2
NP_694743

Location (UCSC) Chr 17: 5 – 5.03 Mb Chr 11: 70.7 – 70.73 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Kinesin-like protein KIF1C is a protein that in humans is encoded by the KIF1C gene.[3][4] Kif1C is a fast, non-processive, plus-end directed microtubule motor.[5] Kif1C transports α5β1-integrins in human cells.[6]

Interactions[edit]

KIF1C has been shown to interact with PTPN21[3] and YWHAG.[7]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ a b Dorner C, Ciossek T, Muller S, Moller PH, Ullrich A, Lammers R (Sep 1998). "Characterization of KIF1C, a new kinesin-like protein involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum". J Biol Chem. 273 (32): 20267–75. doi:10.1074/jbc.273.32.20267. PMID 9685376. 
  4. ^ "Entrez Gene: KIF1C kinesin family member 1C". 
  5. ^ Rogers KR, Weiss S, Crevel I, Brophy PJ, Geeves M, Cross R (September 2001). "KIF1D is a fast non-processive kinesin that demonstrates novel K-loop-dependent mechanochemistry". EMBO J. 20 (18): 5101–13. doi:10.1093/emboj/20.18.5101. PMC 125638Freely accessible. PMID 11566875. 
  6. ^ Theisen U, Straube E, Straube A (December 2012). "Directional persistence of migrating cells requires Kif1C-mediated stabilization of trailing adhesions". Dev. Cell. 23 (6): 1153–66. doi:10.1016/j.devcel.2012.11.005. PMID 23237952. 
  7. ^ Dorner C, Ullrich A, Häring HU, Lammers R (November 1999). "The kinesin-like motor protein KIF1C occurs in intact cells as a dimer and associates with proteins of the 14-3-3 family". J. Biol. Chem. 274 (47): 33654–60. doi:10.1074/jbc.274.47.33654. PMID 10559254. 

Further reading[edit]