Ethinylestradiol/drospirenone

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Ethinylestradiol/drospirenone
Ethinylestradiol.svg
Ethinylestradiol
Drospirenone.svg
Drospirenone
Combination of
EthinylestradiolEstrogen
DrospirenoneProgestogen; Progestin; Antimineralocorticoid; Antiandrogen
Clinical data
Trade namesWith 30 μg ethinylestradiol: Yasmin, others
With 20 μg ethinylestradiol: Yaz, Yasminelle, others
Other namesEE/DRSP
AHFS/Drugs.comProfessional Drug Facts
MedlinePlusa601050
License data
Pregnancy
category
  • AU: B3[1]
  • US: N (Not classified yet)[1]
Routes of
administration
By mouth
Drug classEstrogen; Progestin; Progestogen; Antimineralocorticoid; Antiandrogen
ATC code
Legal status
Legal status
Identifiers
KEGG

Ethinylestradiol/drospirenone (EE/DRSP), sold under the brand name Yasmin among others, is a combination of ethinylestradiol (EE), an estrogen, and drospirenone (DRSP), a progestin, antimineralocorticoid, and antiandrogen, which is used as a birth control pill to prevent pregnancy in women.[2][3][4][5] It is also indicated for the treatment of moderate acne, premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), and dysmenorrhea (painful menstruation) in women.[3] The medication is taken by mouth and contains 30 μg EE and 3 mg DRSP per tablet (brand names Yasmin, others) or 20 μg EE and 3 mg DRSP per tablet (brand names Yaz, Yasminelle, Nikki, others).[4][5] A formulation with levomefolic acid (vitamin B9) has also been marketed (brand names Beyaz, Safyral, others), with similar indications.[6][7] EE/DRSP is marketed widely throughout the world.[8]

In 2017, it was the 98th most commonly prescribed medication in the United States, with more than eight million prescriptions.[9][10]

See also[edit]

References[edit]

  1. ^ a b "Drospirenone / estradiol (Angeliq) Use During Pregnancy". Drugs.com. 6 September 2018. Retrieved 18 March 2020.
  2. ^ https://adisinsight.springer.com/drugs/800007379
  3. ^ a b https://adisinsight.springer.com/drugs/800017043
  4. ^ a b https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021098s028lbl.pdf
  5. ^ a b "Yaz" (PDF). Retrieved October 31, 2017.
  6. ^ https://adisinsight.springer.com/drugs/800032716
  7. ^ https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022532s001lbl.pdf
  8. ^ https://www.drugs.com/international/drospirenone.html
  9. ^ "The Top 300 of 2020". ClinCalc. Retrieved 11 April 2020.
  10. ^ "Drospirenone; Ethinyl Estradiol - Drug Usage Statistics". ClinCalc. Retrieved 11 April 2020.

External links[edit]