Side effects of penicillin: Difference between revisions
→Uncommon (<1%): ce |
→In animals: +content+ref |
||
| Line 91: | Line 91: | ||
==In animals== |
==In animals== |
||
Animals are often treated with antibiotics for infections they have developed. There are side effects of penicillin when it is used in animals. MRSA may develop in pets as a consequence of treatment. Nutritional deficiencies can develop in pets as a side effect.<ref>{{cite web|url=http://www.dogsnaturallymagazine.com/three-things-every-dog-owner-should-know-about-antibiotics/|title=Three Things Every Dog Owner Should Know About Antibiotics - Dogs Naturally Magazine|date=27 May 2013|publisher=|accessdate=19 May 2017}}</ref> Destruction of the normal protective flora of beneficial bacteria can occur in dogs.<ref>{{cite web|url=https://www.whole-dog-journal.com/issues/7_3/features/Canine-Antibiotics_5612-1.html|title=The Dangers of Antibiotic Misuse and Your Dog - Whole Dog Journal|website=www.whole-dog-journal.com|accessdate=19 May 2017}}</ref> Dogs may have side effects that include: pain in their joints, loss of appetite, vomiting, flatulence (instestinal gas), fungal infections and digestive problems.<ref>{{cite web|url=https://www.reference.com/science/correct-dosage-penicillin-dogs-7dfcff44fff7ef42#|title=What is the correct dosage of penicillin for dogs?|publisher=|accessdate=19 May 2017}}</ref><ref name = vetinfo/> Like humans, dogs can have a similar side effect related to developing a serioys allergy. A serious and possibly fatal anaphylactic can occur. Side effects that are concurrent with anaphylaxis include: breathing problems and shock.<ref name = vetinfo>{{cite web|url=https://www.vetinfo.com/side-effects-penicillin.html|title=Side Effects of Penicillin for Dogs|publisher=}}</ref> |
Animals are often treated with antibiotics for infections they have developed. There are side effects of penicillin when it is used in animals. MRSA may develop in pets as a consequence of treatment. Nutritional deficiencies can develop in pets as a side effect.<ref>{{cite web|url=http://www.dogsnaturallymagazine.com/three-things-every-dog-owner-should-know-about-antibiotics/|title=Three Things Every Dog Owner Should Know About Antibiotics - Dogs Naturally Magazine|date=27 May 2013|publisher=|accessdate=19 May 2017}}</ref> Destruction of the normal protective flora of beneficial bacteria can occur in dogs and horses.<ref>{{cite web|url=https://www.whole-dog-journal.com/issues/7_3/features/Canine-Antibiotics_5612-1.html|title=The Dangers of Antibiotic Misuse and Your Dog - Whole Dog Journal|website=www.whole-dog-journal.com|accessdate=19 May 2017}}</ref><ref name="CostaStämpfli2015">{{cite journal|last1=Costa|first1=Marcio C|last2=Stämpfli|first2=Henry R|last3=Arroyo|first3=Luis G|last4=Allen-Vercoe|first4=Emma|last5=Gomes|first5=Roberta G|last6=Weese|first6=J|title=Changes in the equine fecal microbiota associated with the use of systemic antimicrobial drugs|journal=BMC Veterinary Research|volume=11|issue=1|year=2015|pages=19|issn=1746-6148|doi=10.1186/s12917-015-0335-7}}</ref> |
||
Dogs may have side effects that include: pain in their joints, loss of appetite, vomiting, flatulence (instestinal gas), fungal infections and digestive problems.<ref>{{cite web|url=https://www.reference.com/science/correct-dosage-penicillin-dogs-7dfcff44fff7ef42#|title=What is the correct dosage of penicillin for dogs?|publisher=|accessdate=19 May 2017}}</ref><ref name = vetinfo/> Like humans, dogs can have a similar side effect related to developing a serioys allergy. A serious and possibly fatal anaphylactic can occur. Side effects that are concurrent with anaphylaxis include: breathing problems and shock.<ref name = vetinfo>{{cite web|url=https://www.vetinfo.com/side-effects-penicillin.html|title=Side Effects of Penicillin for Dogs|publisher=}}</ref> |
|||
==Other side effects == |
==Other side effects == |
||
Revision as of 18:53, 19 May 2017
An editor has nominated this article for deletion. You are welcome to participate in the deletion discussion, which will decide whether or not to retain it. |
 | This article or section is in a state of significant expansion or restructuring. You are welcome to assist in its construction by editing it as well. If this article or section has not been edited in several days, please remove this template. If you are the editor who added this template and you are actively editing, please be sure to replace this template with {{in use}} during the active editing session. Click on the link for template parameters to use.
This article was last edited by Barbara (WVS) (talk | contribs) 7 years ago. (Update timer) |
The side effects of penicillin are those bodily responses that show that a person or animal is reacting to penicillin. Some of these reactions are visible and some occur in the body's organs or blood. Penicillin is a widely-used medication that is effective for the treatment of a wide variety of bacterial infections in adults and children. Some side effects are expected, some are common but serious, some are uncommon and not serious and others are rare but serious.[1] The route of administration of penicillin can have an effect on the development of side effects. An example of this is irritation and inflammation that develops at a peripheral infusion site when penicillin is administered intravenously. In addition, penicillin is available in different forms. There are six different penicillin medications. These are penicillin G benzathine, penicillin G potassium, penicillin G procaine, and penicillin V.[2] Side effects may only last for a short time and then go away. Side effects can be relieved in some cases with non pharmacological treatment.[3] Some side effects require treatment to correct potentially serious and sometimes fatal reactions to penicillin.
Cross sensitivities
If someone has developed sensitivity to penicillin, there is a common side effect that can develop when other medications are used. This is the development of cross sensitivities to other antibiotics. If someone has developed side effects when taking penicillin, these side effects may develop with a new medication even though the person has not taken the new medication before. Those medications that may cause a cross sensitivity reaction are: ampicillin, cefazolin, and clooxacillin.[4]
Side effects in adults
Common adverse drug reactions (≥ 1% of people) associated with use of the penicillins include diarrhoea, hypersensitivity, nausea, rash, neurotoxicity, urticaria, and superinfection (including candidiasis). Infrequent adverse effects (0.1–1% of people) include fever, vomiting, erythema, dermatitis, angioedema, seizures (especially in people with epilepsy), and pseudomembranous colitis.[5][subscription required][outdated?]
Very Common (>10% incidence)
Common (1-10% incidence)
- yeast infection
- lack of therapeutic effect[7]
- vaginal itching
- vaginal discharge
- white patches in the mouth and tongue[3]
Uncommon (<1%)
- wheezing[6]
- fever
- joint pain
- lightheadedness
- fainting
- facial edema {puffiness of the face)
- red, scaly skin
- shortness of breath
- skin rash, hives
- irregular breathing[3]
Life threatening
Rare (<0.1%)
- tooth discoloration
- erythema multiforme
- vertigo
- decreased platelet count
- tinnitus
- convulsions
- hypertonia
- cardiac arrest
- cyanosis
- palpitations
- chest pain
- macular rash[8]
- yellow eyes or skin
- stomach or abdominal cramps
- severe abdominal pain
- bloody diarrhea
- depression
- decreased in urine excretion
- sore throat
- bleeding or bruising
- agitation
- combativeness
- anxiety
- confusion
- hallucinations[3]
At high doses
- hypokalemia - low levels of calcium in the blood
- metabolic acidosis - the lowering of blood pH, potentially fatal
- hyperkalemia - the development of high calcium levels in the blood (with penicillin G)[9]
In animals
Animals are often treated with antibiotics for infections they have developed. There are side effects of penicillin when it is used in animals. MRSA may develop in pets as a consequence of treatment. Nutritional deficiencies can develop in pets as a side effect.[10] Destruction of the normal protective flora of beneficial bacteria can occur in dogs and horses.[11][12] Dogs may have side effects that include: pain in their joints, loss of appetite, vomiting, flatulence (instestinal gas), fungal infections and digestive problems.[13][14] Like humans, dogs can have a similar side effect related to developing a serioys allergy. A serious and possibly fatal anaphylactic can occur. Side effects that are concurrent with anaphylaxis include: breathing problems and shock.[14]
Other side effects
Penicillin is known to become less effective as strains of bacteria become resistant.[15]
References
- ^ Valerand, pp. 3–4.
- ^ Karch, p. 115.
- ^ a b c d "Penicillin (Oral Route, Injection Route, Intravenous Route, Intramuscular Route) Side Effects - Mayo Clinic". www.mayoclinic.org. Retrieved 18 May 2017.
- ^ "Pharmaceutical Sciences CSU Parenteral Antibiotic Allergy cross-sensitivity chart" (PDF). Vancouver Acute Pharmaceutical Sciences, Vancouver Hospital & Health Sciences Centre. 2016. Retrieved May 19, 2017.
- ^ Rossi S, ed. (2006). Australian Medicines Handbook. Adelaide: Australian Medicines Handbook. ISBN 0-9757919-2-3.
- ^ a b c Valerand, pp. 989–994.
- ^ Ohlsson, Arne; Shah, Vibhuti S; Ohlsson, Arne (2014). "Intrapartum antibiotics for known maternal Group B streptococcal colonization". doi:10.1002/14651858.CD007467.pub4.
{{cite journal}}: Cite journal requires|journal=(help) - ^ Cooper, Chuck (9 January 2015). "Bioterrorism and Drug Preparedness - Safety of Long Term Therapy with Penicillin and Penicillin Derivatives". www.fda.gov. Retrieved 19 May 2017.
- ^ Potter, p. 897.
- ^ "Three Things Every Dog Owner Should Know About Antibiotics - Dogs Naturally Magazine". 27 May 2013. Retrieved 19 May 2017.
- ^ "The Dangers of Antibiotic Misuse and Your Dog - Whole Dog Journal". www.whole-dog-journal.com. Retrieved 19 May 2017.
- ^ Costa, Marcio C; Stämpfli, Henry R; Arroyo, Luis G; Allen-Vercoe, Emma; Gomes, Roberta G; Weese, J (2015). "Changes in the equine fecal microbiota associated with the use of systemic antimicrobial drugs". BMC Veterinary Research. 11 (1): 19. doi:10.1186/s12917-015-0335-7. ISSN 1746-6148.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ "What is the correct dosage of penicillin for dogs?". Retrieved 19 May 2017.
- ^ a b "Side Effects of Penicillin for Dogs".
- ^ Li, Shunming; Huang, Jingya; Chen, Zhiyao; Guo, Dan; Yao, Zhenjiang; Ye, Xiaohua (2017). "Antibiotic Prevention for Maternal Group B Streptococcal Colonization on Neonatal GBS-Related Adverse Outcomes: A Meta-Analysis". Frontiers in Microbiology. 8. doi:10.3389/fmicb.2017.00374. ISSN 1664-302X.
{{cite journal}}: CS1 maint: unflagged free DOI (link)
Bibliography
- Henry, Norma (2016). RN nursing care of children : review module. Stilwell, KS: Assessment Technologies Institute. ISBN 9781565335714.
- Karch, Amy (2017). Focus on nursing pharmacology. Philadelphia: Wolters Kluwer. ISBN 9781496318213.
- Potter, Patricia (2013). Fundamentals of nursing. St. Louis, Mo: Mosby Elsevier. ISBN 9780323079334.
- Vallerand, April (2017). Davis's drug guide for nurses. Philadelphia: F.A. Davis Company. ISBN 9780803657052.
External links
