TPK1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
TPK1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TPK1, HPP20, THMD5, thiamin pyrophosphokinase 1
External IDs MGI: 1352500 HomoloGene: 6960 GeneCards: TPK1
RNA expression pattern
PBB GE TPK1 221218 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001042482
NM_022445

NM_013861
NM_001311111

RefSeq (protein)

NP_001035947.1
NP_071890.2

NP_001298040.1
NP_038889.1

Location (UCSC) Chr 7: 144.45 – 144.84 Mb Chr 6: 43.35 – 43.67 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Thiamin pyrophosphokinase 1 is an enzyme that in humans is encoded by the TPK1 gene.[3][4]

This gene encodes a protein, that exists as a homodimer, which catalyzes the conversion of thiamine to thiamine pyrophosphate. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Nosaka K, Onozuka M, Kakazu N, Hibi S, Nishimura H, Nishino H, Abe T (May 2001). "Isolation and characterization of a human thiamine pyrophosphokinase cDNA". Biochim Biophys Acta. 1517 (2): 293–7. doi:10.1016/s0167-4781(00)00247-5. PMID 11342111. 
  4. ^ a b "Entrez Gene: TPK1 thiamin pyrophosphokinase 1". 

Further reading[edit]