TTK (gene)

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TTK protein kinase
Protein TTK PDB 2ZMC.png
Rendering based on PDB 2ZMC​.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols TTK ; CT96; ESK; MPH1; MPS1; MPS1L1; PYT
External IDs OMIM604092 MGI1194921 HomoloGene2489 ChEMBL: 3983 GeneCards: TTK Gene
EC number
RNA expression pattern
PBB GE TTK 204822 at tn.png
More reference expression data
Species Human Mouse
Entrez 7272 22137
Ensembl ENSG00000112742 ENSMUSG00000038379
UniProt P33981 Q8BX21
RefSeq (mRNA) NM_001166691 NM_001110265
RefSeq (protein) NP_001160163 NP_001103735
Location (UCSC) Chr 6:
80 – 80.04 Mb
Chr 9:
83.83 – 83.87 Mb
PubMed search [1] [2]

Dual specificity protein kinase TTK also known as Mps1 is an enzyme that in humans is encoded by the TTK gene.[1][2]


  1. ^ Mills GB, Schmandt R, McGill M, Amendola A, Hill M, Jacobs K, May C, Rodricks AM, Campbell S, Hogg D (Aug 1992). "Expression of TTK, a novel human protein kinase, is associated with cell proliferation". J Biol Chem 267 (22): 16000–6. PMID 1639825. 
  2. ^ "Entrez Gene: TTK TTK protein kinase". 

Further reading[edit]