PASK

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For the airport in Alaska with ICAO code PASK, see Selawik Airport.
PASK
Protein PASK PDB 1ll8.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases PASK, PASKIN, STK37, PAS domain containing serine/threonine kinase
External IDs MGI: 2155936 HomoloGene: 9038 GeneCards: 23178
RNA expression pattern
PBB GE PASK 213534 s at tn.png

PBB GE PASK 216945 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001252119
NM_001252120
NM_001252122
NM_001252124
NM_015148

NM_080850

RefSeq (protein)

NP_001239048.1
NP_001239049.1
NP_001239051.1
NP_001239053.1
NP_055963.2

NP_543126.2

Location (UCSC) Chr 2: 241.11 – 241.15 Mb Chr 1: 93.31 – 93.34 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

PAS domain-containing serine/threonine-protein kinase is an enzyme that in humans is encoded by the PASK gene.[3][4][5][6]

PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. PASK is an evolutionarily conserved protein present in yeast, flies, and mammals.[supplied by OMIM][6]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Hofer T, Spielmann P, Stengel P, Stier B, Katschinski DM, Desbaillets I, Gassmann M, Wenger RH (Nov 2001). "Mammalian PASKIN, a PAS-serine/threonine kinase related to bacterial oxygen sensors". Biochem Biophys Res Commun. 288 (4): 757–64. doi:10.1006/bbrc.2001.5840. PMID 11688972. 
  4. ^ Rutter J, Michnoff CH, Harper SM, Gardner KH, McKnight SL (Aug 2001). "PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase". Proc Natl Acad Sci U S A. 98 (16): 8991–6. doi:10.1073/pnas.161284798. PMC 55361free to read. PMID 11459942. 
  5. ^ da Silva Xavier G, Rutter J, Rutter GA (Jun 2004). "Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose". Proc Natl Acad Sci U S A. 101 (22): 8319–24. doi:10.1073/pnas.0307737101. PMC 420392free to read. PMID 15148392. 
  6. ^ a b "Entrez Gene: PASK PAS domain containing serine/threonine kinase". 

Further reading[edit]