VRK2

VRK2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2V62
Identifiers
Aliases	VRK2, vaccinia related kinase 2, VRK serine/threonine kinase 2
External IDs	OMIM: 602169; MGI: 1917172; HomoloGene: 55966; GeneCards: VRK2; OMA:VRK2 - orthologs
EC number	2.7.11.1
Gene location (Human)
Chr.	Chromosome 2 (human)
End	58,159,920 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	26,543,999 bp
RNA expression pattern
	Top expressed in
	monocyte; ; Achilles tendon; ; corpus callosum; ; right ventricle; ; islet of Langerhans; ; rectum; ; parotid gland; ; internal globus pallidus; ; smooth muscle tissue; ; lymph node;
	Top expressed in
	blood; ; spleen; ; spermatocyte; ; thymus; ; morula; ; yolk sac; ; subcutaneous adipose tissue; ; vas deferens; ; spermatid; ; seminiferous tubule;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; protein domain specific binding; kinase activity; protein serine/threonine kinase activity; protein binding; ATP binding; protein kinase binding;
Cellular component	cytoplasm; integral component of membrane; endoplasmic reticulum membrane; mitochondrial membranes; membrane; endoplasmic reticulum; mitochondrion; nucleus; protein-containing complex;
Biological process	regulation of MAPK cascade; regulation of interleukin-1-mediated signaling pathway; phosphorylation; protein phosphorylation; peptidyl-serine phosphorylation; protein autophosphorylation; cellular response to oxidative stress; viral process; regulation of cell shape; peptidyl-threonine phosphorylation;
	Sources:Amigo / QuickGO
Orthologs
	7444
	69922
	ENSG00000028116
	ENSMUSG00000064090
	Q86Y07
	Q8BN21
NM_001130480; NM_001130481; NM_001130482; NM_001130483; NM_001288836;
	NM_001288837; NM_001288838; NM_001288839; NM_006296
	NM_001252447; NM_027260
NP_001123952; NP_001123953; NP_001123954; NP_001123955; NP_001275765;
	NP_001275766; NP_001275767; NP_001275768; NP_006287
	NP_001239376; NP_081536
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase VRK2 is an enzyme that in humans is encoded by the VRK2 gene.^[5]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000028116 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000064090 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: VRK2 vaccinia related kinase 2".

References

Further reading