List of foreign MLS players
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This is a list of foreign players in Major League Soccer. The following players:
- Have played at least one MLS regular season game. Players who were signed by MLS clubs, but only played in playoff games, U.S. Open Cup games, or did not play in any competitive games at all, are not included.
- Are considered foreign, i.e., outside Canada or the United States determined by the following:
- A player is considered foreign if he is not eligible to play for the national team of Canada or the United States.
More specifically,
- If a player has been capped on international level, the national team is used; if he has been capped by more than one country, the highest level (or the most recent) team is used. These include American and Canadian players with dual citizenship.
- If a player has not been capped on international level, his country of birth is used, except those who were born abroad from American or Canadian parents, or moved to Canada or the United States at a young age, and those who clearly indicated to have switched his nationality to another nation.
Up to now, 128 different nations have been represented in MLS. Zambia was the most recent nation to be represented when Aimé Mabika made his MLS debut playing for Inter Miami CF.
In bold: players who have played at least one MLS game in the most recent season (2021 Major League Soccer season), and are still at the clubs for which they have played. This does not include current players of a MLS club who have not played a MLS game in the current season.
Africa (CAF)
- Raïs M'Bolhi – Philadelphia – 2014–15[b FRA][c FRA U18][c FRA U17]
- Saphir Taïder – Montreal – 2018–20[b FRA][c FRA U20][c FRA U19][c FRA U18]
- Edgar Bartolomeu – MetroStars – 2003
- Fernando Fernandes – MetroStars – 1999
- Bruno Gaspar – Vancouver – 2021 [b POR][c POR U21][c POR U18][c POR U16][c POR U15]
- Jerson Monteiro – Chicago – 2007
- Femi Hollinger-Janzen – New England – 2016–18
- Cédric Hountondji – New York City FC – 2018[b FRA][c FRA U21][c FRA U18][c FRA U17][c FRA U16]
- Dipsy Selolwane – Chicago, Salt Lake – 2002–05
- Anatole Abang – New York Red Bulls – 2015–16
- Brian Anunga – Nashville – 2020–
- Stephane Assengue – New England – 2009
- Yazid Atouba – Chicago – 2013
- Eric Ayuk – Philadelphia – 2015–16
- Samuel Ekemé – Kansas City – 1996
- Charles Eloundou – Colorado – 2014–15
- Wilfrid Kaptoum – New England – 2021–
- Olivier Mbaizo – Philadelphia – 2018–
- Matthew Mbuta – New York Red Bulls – 2008–09
- Alexandre Morfaw – Vancouver – 2011
- Joseph Nane – Toronto, Colorado – 2010–12
- Hassan Ndam – New York Red Bulls – 2017–18
- Alain N'Kong – Chicago – 2005–06
- Marius Obekop – New York Red Bulls – 2013–15
- Ambroise Oyongo – New York Red Bulls, Montreal – 2014–17
- Frantz Pangop – Minnesota – 2018
- Franck Songo'o – Portland – 2012[c FRA U19]
- Tony Tchani – New York Red Bulls, Toronto, Columbus, Vancouver, Chicago – 2010–18[c USA]
- Nouhou Tolo – Seattle – 2017–
- Paulo Dos Santos – New England – 1999
- Jair – New England, San Jose, Tampa Bay – 1998–99, 2001
- Jamiro Monteiro – Philadelphia, San Jose – 2019–[b NED]
- Kévin Oliveira – Kansas City – 2017
- Wilfried Zahibo – New England, Houston – 2018–21[b FRA]
- Dimitry Imbongo – New England – 2012–14
- Phanuel Kavita – Salt Lake – 2015–16
- Larrys Mabiala – Portland – 2017–[b FRA][c FRA U21]
- Cedrick Mabwati – Columbus – 2015–16
- Chris Mavinga – Toronto – 2017–[b FRA][c FRA U21][c FRA U20][c FRA U19][c FRA U18]
- Danny Mwanga – Philadelphia, Portland, Colorado, Orlando – 2010–15
- Ange N'Silu – D.C. United – 2009
- Michee Ngalina – Philadelphia, Los Angeles FC – 2019, 2021
- Steve Zakuani – Seattle, Portland – 2009–14
- Omar Gaber – Los Angeles FC – 2018
- Ali Ghazal – Vancouver – 2017–18
- Ahmed Hamdy – Montreal – 2021–
- Amro Tarek – Columbus, Orlando, New York Red Bulls – 2016, 2018–21[b USA]
- Henok Goitom – San Jose – 2016[b SWE][c SWE U21]
- Mohammed Saeid – Columbus, Minnesota, Colorado – 2015–17[b SWE]
- Fuad Ibrahim – Toronto – 2008–10[c USA U20][c USA U17]
- Mamadou Danso – Portland, Montreal – 2011–14
- Emmanuel Gómez – Toronto – 2009
- Modou Jadama – Portland – 2018–19
- Mustapha Jarju – Vancouver – 2011
- Omar Jasseh – San Jose – 2010–11
- Ismaila Jome – Minnesota, Portland – 2017, 2021
- Kekuta Manneh – Vancouver, Columbus, Cincinnati, New England, Austin – 2013–17, 2019–21
- Abdoulie Mansally – New England, Salt Lake, Houston – 2007–16
- Sainey Nyassi – New England, D.C. United – 2007–13
- Sanna Nyassi – Seattle, Colorado, Montreal, Chicago, San Jose – 2009–15
- Amadou Sanyang – Toronto, Seattle – 2009–11
- Omar Sowe – New York Red Bulls – 2021–
- Mohammed Abu – Columbus, D.C. United – 2017–18, 2020
- Lalas Abubakar – Columbus, Colorado – 2017–
- David Accam – Chicago, Philadelphia, Columbus, Nashville – 2015–20
- Joe Addo – Tampa Bay, MetroStars – 1999–2003
- Bismark Adjei-Boateng – Colorado – 2017–18
- Harrison Afful – Columbus – 2015–
- Junior Agogo – Chicago, Colorado, San Jose – 2000–01
- Kalif Alhassan – Portland – 2011–14
- Emmanuel Appiah – Kansas City – 2016
- Samuel Appiah – Houston – 2010
- Isaac Atanga – Cincinnati – 2021–
- Francis Atuahene – Dallas – 2019
- Gideon Baah – New York Red Bulls – 2016
- Fifi Baiden – Columbus – 2014
- Latif Blessing – Kansas City, Los Angeles FC – 2017–
- Emmanuel Boateng – LA Galaxy, D.C. United, Columbus, New England – 2016–
- Abu Danladi – Minnesota, Nashville – 2017–
- Edwin Gyasi – Dallas – 2019[b NED]
- Salou Ibrahim – New York Red Bulls – 2010
- Sumed Ibrahim – Chicago – 2004
- Samuel Inkoom – D.C. United – 2014
- Louis Ken-Kwofie – MetroStars – 1996
- Gershon Koffie – Vancouver, New England – 2011–17
- Nana Kuffour – D.C. United – 2004–05
- Adam Larsen Kwarasey – Portland – 2015–16[b NOR][c NOR U21]
- Jonathan Mensah – Columbus – 2017–
- Patrick Nyarko – Chicago, D.C. United – 2008–17
- Anthony Obodai – Houston – 2010
- Dominic Oduro – Dallas, New York Red Bulls, Houston, Chicago, Columbus, Toronto, Montreal, San Jose – 2006–18
- Ebenezer Ofori – New York City FC – 2018–19
- Kofi Opare – LA Galaxy, D.C. United, Colorado – 2013–19
- Edward Opoku – Columbus – 2018
- Kwadwo Opoku – Los Angeles FC – 2020–
- Emmanuel Osei – New England – 2009–10
- Leonard Owusu – Vancouver – 2020–
- Kwadwo Poku – New York City FC – 2015–16
- Lloyd Sam – New York Red Bulls, D.C. United – 2012–17[b ENG][c ENG U20]
- Samuel Tetteh – New York Red Bulls – 2020
- Ema Twumasi – Dallas – 2018–
- Joshua Yaro – Philadelphia – 2016–18
- Ishmael Yartey – Portland – 2015
- Yaw Yeboah – Columbus – 2022–
- Hadji Barry – Orlando – 2016–17
- Lass Bangoura – Vancouver – 2019
- Florentin Pogba – Atlanta – 2019[c FRA U20]
- Gerso Fernandes – Kansas City – 2017–20
- Nanu – Dallas – 2022–
- Sambinha – New England – 2016[b POR]
- Benjamin Angoua – New England – 2017
- Yannick Boli – Colorado – 2018[b FRA]
- Didier Drogba – Montreal – 2015–16
- Jean-Martial Kipré – Salt Lake – 2007
- Ismaël Koné – Montréal – 2022–
- Guy-Roland Kpene – D.C. United – 2007
- Aké Arnaud Loba – Nashville – 2021–
- Arsène Oka – New England – 2007
- Olivier Tébily – Toronto – 2008
- Handwalla Bwana – Seattle, Nashville – 2018–
- Lawrence Olum – Kansas City, Portland, Minnesota – 2011–14, 2016–19
- Victor Wanyama – Montreal – 2020–
- Michael Butler – MetroStars – 2001
- Louis Crayton – D.C. United – 2008–09
- Francis Doe – New York Red Bulls, D.C. United – 2007–09
- Sam Forko – MetroStars – 2002
- Willis Forko – Salt Lake – 2006–07
- Chris Gbandi – Dallas – 2003–07
- Sam Johnson – Salt Lake – 2019–20
- Zizi Roberts – Colorado – 2003–04
- Musa Shannon – Tampa Bay, Colorado – 1997–99, 2002[b USA]
- Adam Smarte – San Jose – 2008
- Melvin Tarley – Salt Lake, Colorado – 2005–06
- Patrick Weah – Minnesota – 2021–
- Mohamed El Monir – Orlando, Los Angeles FC – 2018–20
- Ismael Tajouri-Shradi – New York City FC, Los Angeles FC – 2018–[b SUI]
- Romain Métanire – Minnesota – 2019–[b FRA]
- Rayan Raveloson – LA Galaxy – 2021–
- Kalifa Cissé – New England – 2013[b FRA]
- Youba Diarra – New York Red Bulls – 2021
- Bakaye Dibassy – Minnesota – 2020–[b FRA]
- Daouda Kanté – New England – 2002–04
- Ibrahim Kante – New England – 2003
- Bakary Soumaré – Chicago, Philadelphia, Montreal – 2007–09, 2012–15
- Djimi Traoré – Seattle – 2013–14[b FRA]
- Mehdi Ballouchy – Salt Lake, Colorado, New York Red Bulls, San Jose, Vancouver, New York City FC – 2006–16
- Ahmed Kantari – Toronto – 2015[b FRA]
- Youness Mokhtar – Columbus – 2019–20[b NED][c NED U19][c NED U17]
- Adrien Regattin – Cincinnati – 2020[b FRA]
- Monsef Zerka – New England – 2011[b FRA]
- Chiquinho Conde – New England, Tampa Bay – 1997
- Tico-Tico – Tampa Bay – 2000
- Ifunanyachi Achara – Toronto – 2020–
- Fanendo Adi – Portland, Cincinnati, Columbus, Minnesota – 2014–21
- Ade Akinbiyi – Houston – 2009[b ENG]
- Gbenga Arokoyo – Portland – 2016
- Bright Dike – Portland, Toronto – 2011–15[b USA]
- Connally Edozien – New England – 2005
- Emmanuel Ekpo – Columbus – 2008–11
- Michael Emenalo – San Jose – 1996–97
- Sunusi Ibrahim – Montreal – 2021–
- James Igbekeme – Columbus – 2022–
- Kennedy Igboananike – Chicago, D.C. United – 2015–16
- Nosa Igiebor – Vancouver – 2017
- Benedict Iroha – D.C. United – 1997
- Obafemi Martins – Seattle – 2013–15
- Manny Motajo – LA Galaxy, New England – 1996, 1998–99
- Chinonso Offor – Chicago – 2021–
- Uche Okafor – Kansas City – 1996–2000
- Francis Okaroh – New England, Chicago, Miami Fusion – 1996–2000
- Orji Okwonkwo – Montreal – 2019–20
- Rasheed Olabiyi – Houston – 2015
- Patrick Olalere – New England – 1997
- Stephen Sunday – Salt Lake – 2016–18[c ESP U21][c ESP U20][c ESP U19]
- Abdul Rwatubyaye – Kansas City – 2019
- Dominique Badji – Colorado, Dallas, Nashville – 2015–
- Bouna Coundoul – Colorado, New York Red Bulls – 2006–11
- Mamadou Diallo – Tampa Bay, New England, MetroStars – 2000–02
- Zakaria Diallo – Montreal – 2019[b FRA]
- Birahim Diop – MetroStars, Kansas City – 2002, 2010–11
- Clément Diop – LA Galaxy, Montreal, Inter Miami – 2016–17, 2019–[b FRA][c FRA U19]
- Moussa Djitté – Austin – 2021–
- Mamadou Fall – Los Angeles FC – 2021–
- Macoumba Kandji – New York Red Bulls, Colorado, Houston – 2008–12
- Joseph Niouky – New England – 2010
- Lamine Sané – Orlando – 2018–19[b FRA]
- Khaly Thiam – Chicago – 2016
- Mohamed Traore – Los Angeles FC – 2020–
- Abdul Thompson Conteh – San Jose, D.C. United – 2000–02
- Alhaji Kamara – D.C. United – 2016–17
- Kei Kamara – Columbus, San Jose, Houston, Kansas City, New England, Vancouver, Colorado, Minnesota, Montréal – 2006–13, 2015–20, 2022–
- Michael Lahoud – Chivas USA, Philadelphia – 2009–15
- Augustine Williams – LA Galaxy – 2021
- Stephen Armstrong – D.C. United, Kansas City, Columbus – 2001–03, 2005[b ENG]
- Derek Backman – Tampa Bay – 1996–97
- Shaun Bartlett – Colorado, MetroStars – 1996–97
- Danleigh Borman – New York Red Bulls, Toronto – 2008–11
- Richard Farrer – Dallas – 1996–2002
- Bongokuhle Hlongwane – Minnesota – 2022–
- Doctor Khumalo – Columbus – 1996–97
- Thabiso Khumalo – D.C. United – 2008–10
- Ivan McKinley – Tampa Bay, New England, Miami Fusion, D.C. United – 1996–2002
- Lindo Mfeka – San Jose – 2017
- Kamohelo Mokotjo – Cincinnati – 2020–21
- Toni Nhleko – Dallas – 2003–04
- Ethen Sampson – Vancouver – 2014–15
- Davide Somma – San Jose – 2008–09
- Machop Chol – Atlanta – 2021–
- Irakoze Donasiyano – Nashville – 2021–
- Nizar Khalfan – Vancouver – 2011
- Abbe Ibrahim – MetroStars, Toronto – 2005, 2007
- Jasser Khmiri – Vancouver – 2019–20
- Micheal Azira – Seattle, Colorado, Montreal, Chicago – 2014–20
- Tenywa Bonseu – Chicago, Columbus, Dallas, MetroStars – 2000–04
- Peter Byaruhanga – Kansas City – 2000
- Joel Kitamirike – Columbus – 2006
- Edward Kizza – New England – 2021–
- Mustafa Kizza – Montreal – 2020–21
- Ibrahim Sekagya – New York Red Bulls – 2013–14
- Robert Ssejjemba – D.C. United – 2006
- Brian Umony – Portland – 2011
- Aimé Mabika – Inter Miami – 2021–
- Mubarike Chisoni – LA Galaxy – 2005
- Kheli Dube – New England – 2008–11
- Neathan Gibson – Colorado – 2001
- Teenage Hadebe – Houston – 2021–
- Joseph Ngwenya – LA Galaxy, Columbus, Houston, D.C. United – 2004–07, 2010–11
- Vitalis Takawira – Kansas City – 1996–99
Asia (AFC)
- Adam Najem – Philadelphia – 2017[b USA]
- Danny Allsopp – D.C. United – 2010
- Tim Cahill – New York Red Bulls – 2012–14[c WSM U20][c WSM U17]
- David Carney – New York Red Bulls – 2013
- Milos Degenek – Columbus – 2022–
- Bernie Ibini-Isei – Vancouver – 2017–18[b NGA]
- Andy Rose – Seattle, Vancouver – 2012–15, 2019–21
- Brad Smith – Seattle, D.C. United – 2018–[c ENG U20][c ENG U19][c ENG U17]
- Tan Long – Vancouver, D.C. United – 2011–12
- A. J. DeLaGarza – LA Galaxy, Houston, Inter Miami, New England – 2009–[b USA][c USA]
- Ryan Guy – New England – 2011–13[b USA]
- Brandon McDonald – LA Galaxy, San Jose, D.C. United, Salt Lake – 2008–13[b USA]
- Erik Ustruck – Houston – 2009[b USA][c USA U20]
- Khodadad Azizi – San Jose – 2000
- Steven Beitashour – San Jose, Vancouver, Toronto, Los Angeles FC, Colorado – 2010–19, 2021–[b USA]
- Mohammad Khakpour – MetroStars – 1999–2000
- Arash Noamouz – LA Galaxy – 1996
- Jun Marques Davidson – Vancouver – 2012–13
- Tsubasa Endoh – Toronto– 2016–17, 2019–21
- Akira Kaji – Chivas USA – 2014
- Kosuke Kimura – Colorado, Portland, New York Red Bulls – 2007–14
- Daigo Kobayashi – Vancouver, New England – 2013–17
- Ken Krolicki – Montreal – 2018–19
- Yuya Kubo – Cincinnati – 2020–
- Masato Kudo – Vancouver – 2016
- Terukazu Tanaka – Salt Lake – 2012
- Hong Myung-bo – LA Galaxy – 2003–04
- Hwang In-beom – Vancouver – 2019–20
- Kim Kee-hee – Seattle – 2018–19
- Kim Moon-hwan – Los Angeles FC – 2021–
- Lee Young-pyo – Vancouver – 2012–13
- Soony Saad – Kansas City – 2011–14, 2017[b USA][c USA U20][c USA U17]
- Johann Noetzel – Dallas – 2000[b USA]
- Nazmi Albadawi – Cincinnati – 2019
- Shaker Asad – New England – 2000–02
- Demitrius Omphroy – Toronto – 2011[b USA][c PAN U21][c USA U17]
- Martin Steuble – Kansas City – 2014[b SUI]
- Gabriel Somi – New England – 2018[b SWE]
Europe (UEFA)
- Shkëlzen Gashi – Colorado– 2016–18[b SUI][c SUI U21][c SUI U19][c SUI U17]
- Jahmir Hyka – San Jose – 2017–18
- Hamdi Salihi – D.C. United – 2012
- Artur Aghasyan – Salt Lake – 2011
- David Arshakyan – Chicago – 2016–17[b RUS]
- Harut Karapetyan – LA Galaxy, San Jose, Tampa Bay – 1996–2000
- Yura Movsisyan – Kansas City, Salt Lake, Chicago – 2006–09, 2016–18[b AZE–URS]
- Lucas Zelarayán – Columbus – 2020–[b ARG]
- Christian Fuchs – Charlotte – 2022–
- Michael Gspurning – Seattle – 2012–13
- Andi Herzog – LA Galaxy – 2004
- Andreas Ivanschitz – Seattle – 2015–16
- Ercan Kara – Orlando – 2022–
- Ernst Öbster – New York Red Bulls – 2009
- Thomas Piermayr – Colorado – 2014
- Emanuel Pogatetz – Columbus – 2014–15
- Daniel Royer – New York Red Bulls – 2016–21
- Markus Schopp – New York Red Bulls – 2006–07
- Sasha Gotsmanov – Colorado – 2005
- Laurent Ciman – Montreal, Los Angeles FC, Toronto – 2015–20
- Nansha Kalonji – MetroStars – 1999
- Roland Lamah – Dallas, Cincinnati – 2017–19[b CIV]
- Logan Ndenbe – Kansas City – 2022–
- Jelle Van Damme – LA Galaxy – 2016–17
- Mikael Yourassowsky – Toronto – 2011
- Said Fazlagić – D.C. United – 1996
- Baggio Hušidić – Chicago, LA Galaxy – 2009–11, 2014–18
- Haris Medunjanin – Philadelphia, Cincinnati – 2017–[c NED U21]
- Refik Šabanadžović – Kansas City – 1998–99[b MNE–YUG 1]
- Siniša Ubiparipović – New York Red Bulls, Montreal – 2007–10, 2012–13
- Kalin Bankov – Tampa Bay – 2000–01
- Stefan Dimitrov – Chicago – 2009–10
- Galin Ivanov – D.C. United – 2003
- Stanislav Ivanov – Chicago – 2021–
- Anton Nedyalkov – Dallas – 2018
- Hristo Stoichkov – Chicago, D.C. United – 2000–03
- Leonard Bisaku – Columbus – 2006
- Toni Datković – Salt Lake – 2021
- Goran Hunjak – Tampa Bay, Kansas City – 1996, 1998
- Kristijan Kahlina – Charlotte – 2022–
- Franko Kovačević – Cincinnati – 2020–21
- Damir Kreilach – Salt Lake – 2018–
- Marko Marić – Chicago – 2011
- Marko Marić– Houston – 2020–21[b AUT][c AUT U16]
- Josip Mikulić – Chicago – 2011[b BIH–YUG]
- Roberto Punčec – Kansas City – 2020–21
- Dario Župarić – Portland – 2020–[c BIH U19]
- Marinos Tzionis – Kansas City – 2022–
- Bořek Dočkal – Philadelphia – 2018
- Jani Galik – New England – 2006
- Luboš Kubík – Chicago, Dallas – 1998–2001
- Zdeněk Ondrášek – Dallas – 2019–20
- Malte Amundsen – New York City FC – 2021–
- Ronnie Ekelund – San Jose – 2001–04
- Niko Hansen – Columbus, Houston, Minnesota – 2017–
- David Jensen – New York Red Bulls – 2020
- Mathias Jørgensen – New York Red Bulls – 2019–20
- Bashkim Kadrii – Minnesota – 2017
- Emil Larsen – Columbus – 2016
- Rajko Lekić – New England – 2011
- Philip Lund – Seattle – 2013
- Miklos Molnar – Kansas City – 2000
- Younes Namli – Colorado – 2020–21
- Brian Nielsen – New York Red Bulls – 2010–11
- Jimmy Nielsen – Kansas City – 2010–13
- David Ousted – Vancouver, D.C. United, Chicago – 2013–19
- Christian Sivebæk – Seattle – 2012
- Mo Adams – Chicago, Atlanta, Inter Miami – 2018–
- Korede Aiyegbusi – Kansas City – 2010–12
- Brandon Austin – Orlando – 2021[c USA U18]
- Jack Barmby – Portland – 2016–18
- David Beckham – LA Galaxy – 2007–12
- Luis Binks – Montreal – 2020[c SCO U18]
- Ian Bishop – Miami Fusion – 2001
- Tyler Blackett – Cincinnati – 2021–
- Jamal Blackman – Los Angeles FC – 2021
- Luke Boden – Orlando – 2015–16
- Jonathan Bond – LA Galaxy – 2021–[c WAL U19][c WAL U17]
- John Bostock – Toronto – 2013
- Chris Brown – Dallas – 1998
- Ian Butterworth – Colorado – 1996
- Tony Caig – Houston – 2008
- Kasali Yinka Casal – D.C. United – 2007
- Ashley Cole – LA Galaxy – 2016–18
- Terry Cooke – Colorado – 2005–09
- John Cunliffe – Chivas USA, San Jose – 2007–08
- Jermain Defoe – Toronto – 2014
- Danny Dichio – Toronto – 2007–09
- Paul Dougherty – New York Red Bulls, Tampa Bay, Chicago, Colorado – 1998–2000
- Andrew Driver – Houston – 2013–14[c SCO U16]
- Richard Eckersley – Toronto, New York Red Bulls – 2011–14
- Tom Edwards – New York Red Bulls – 2021–
- Mandela Egbo – New York Red Bulls – 2020–21
- Jack Elliott – Philadelphia – 2017–
- Hogan Ephraim – Toronto – 2013
- Shay Facey – New York City FC – 2015
- Steven Gerrard – LA Galaxy – 2015–16
- Kieran Gibbs – Inter Miami – 2021–
- Jason Griffiths – New England – 2010
- Steve Guppy – D.C. United – 2005
- Jack Gurr – Atlanta – 2021
- Calvin Harris – Cincinnati – 2021–
- Jack Harrison – New York City FC – 2016–17
- Aidan Heaney – New England – 1996
- Harrison Heath – Orlando, Atlanta, Minnesota – 2015–18
- Seb Hines – Orlando – 2015–17
- Joe Holland – Houston – 2017
- Steve Howey – New England – 2004
- Darren Huckerby – San Jose – 2008–09
- Andy Iro – Columbus, Toronto – 2008–11
- Danny Jackson – Colorado – 2002
- Eddie Johnson – Portland – 2011
- Aaron Jones – Philadelphia – 2017
- Matt Jones – Philadelphia – 2016
- Zat Knight – Colorado – 2014
- Frank Lampard – New York City FC – 2015–16
- Michael Mancienne – New England – 2018–20
- Tyrone Mears – Seattle, Atlanta, Minnesota – 2015–18
- Luke Moore – Chivas USA, Toronto – 2014–15
- Taylor Morgan – Toronto – 2013
- Luke Mulholland – Salt Lake – 2014–19
- Jordon Mutch – Vancouver – 2018
- Lewis Neal – D.C. United, Orlando – 2012–15
- Nedum Onuoha – Salt Lake – 2018–20
- Bradley Orr – Toronto – 2014
- Kyle Patterson – LA Galaxy – 2009
- Dion Pereira – Atlanta – 2019
- Jack Price – Colorado – 2018–
- Nigel Reo-Coker – Vancouver, Chivas USA, Montreal – 2013–15[b SLE]
- Rohan Ricketts – Toronto – 2008–09
- Paul Rideout – Kansas City – 1998
- Liam Ridgewell – Portland – 2014–18
- Luke Rodgers – New York Red Bulls – 2011
- John Rooney – New York Red Bulls – 2011
- Wayne Rooney – D.C. United – 2018–19
- Darel Russell – Toronto – 2013
- Richard Sharpe – Colorado – 1996
- Ryan Shawcross – Inter Miami – 2021
- Jay Simpson – Philadelphia – 2017–18
- Josh Sims – New York Red Bulls – 2019
- Kimarni Smith – D.C. United – 2021–
- Ryan Smith – Kansas City, Chivas USA – 2010–12
- Jordan Stewart – San Jose – 2013–16
- Dan Stratford – D.C. United – 2008
- Rob Vincent – D.C. United – 2016–17
- Anton Walkes – Atlanta, Charlotte – 2017, 2020–
- Charlie Ward – Houston – 2017–18
- Grant Ward – Chicago – 2014
- Matt Watson – Vancouver, Chicago – 2012–15
- Andy Welsh – Toronto – 2007
- Mark Wilson – Dallas – 2005–06
- Ian Woan – Columbus, Miami Fusion – 2001
- Chris Woods – Colorado – 1996
- Bradley Wright-Phillips – New York Red Bulls, Los Angeles FC, Columbus – 2013–21
- Shaun Wright-Phillips – New York Red Bulls – 2015–16
- Laurence Wyke – Atlanta – 2020
- Dru Yearwood – New York Red Bulls – 2020–
- Joel Lindpere – New York Red Bulls, Chicago – 2010–13
- Erik Sorga – D.C. United – 2020–21
- Markus Halsti – D.C. United – 2015
- Niko Hämäläinen – Los Angeles FC, LA Galaxy – 2019, 2021[b USA]
- Lassi Lappalainen – Montreal – 2019–
- Robin Lod – Minnesota – 2019–
- Jukka Raitala – Columbus, Montreal, Minnesota – 2017–21
- Alexander Ring – New York City FC, Austin – 2017–
- Rasmus Schüller – Minnesota – 2017–19
- Toni Ståhl – Philadelphia – 2010
- Antti Sumiala – Kansas City – 2005
- Teemu Tainio – New York Red Bulls – 2011–12
- Robert Taylor – Inter Miami – 2022–
- Simo Valakari – Dallas – 2004–06
- Mika Väyrynen – LA Galaxy – 2015[b SWE]
- Romain Alessandrini – LA Galaxy – 2017–19
- Mouloud Akloul – Vancouver – 2011
- Julien Baudet – Colorado – 2009–10
- Pascal Bedrossian – Chicago – 2006–07
- Nicolas Benezet – Toronto, Colorado, Seattle – 2019–21
- Vincent Bezecourt – New York Red Bulls – 2017–19
- Frédéric Brillant – New York City FC, D.C. United – 2016–21
- Kévin Cabral – LA Galaxy – 2021–
- Rudy Camacho – Montreal – 2018–
- Hassoun Camara – Montreal – 2012–17
- Benoît Cheyrou – Toronto – 2015–17
- Michaël Ciani – LA Galaxy – 2017–18
- Abdoulaye Cissoko – Seattle – 2021–
- Aurélien Collin – Kansas City, Orlando, New York Red Bulls, Philadelphia – 2011–19
- Yohan Croizet – Kansas City – 2018–19
- Séga Coulibaly – LA Galaxy – 2021–[b MLI]
- Laurent Courtois – Chivas USA, LA Galaxy – 2011–13
- Ousmane Dabo – New England – 2011
- Mathieu Deplagne – Cincinnati – 2019–20
- Bradley Diallo – LA Galaxy – 2017
- Claude Dielna – New England, Portland – 2017–19
- Sofiane Djeffal – D.C. United – 2022–
- Youri Djorkaeff – New York Red Bulls – 2005–06
- Didier Domi – New England – 2011
- Rod Fanni – Montreal – 2018–20
- Samuel Grandsir – LA Galaxy – 2021–
- Léandre Griffit – Columbus – 2010–11
- Eric Hassli – Vancouver, Toronto, Dallas – 2011–13
- Thierry Henry – New York Red Bulls – 2010–14
- Adrien Hunou – Minnesota – 2021–
- Elie Ikangu – New York Red Bulls – 2006–07
- Nicolas Isimat-Mirin – Kansas City – 2021–
- Sébastien Le Toux – Seattle, Philadelphia, Vancouver, New York Red Bulls, Colorado, D.C. United – 2009–17
- Peter Luccin – Dallas – 2013–14
- Péguy Luyindula – New York Red Bulls – 2013–14[b ZAI]
- Paul Marie – San Jose – 2019–
- Blaise Matuidi – Inter Miami – 2020–
- Laurent Merlin – Chivas USA – 2007
- David Milinković – Vancouver – 2020
- Wilfried Moimbé – Minnesota – 2019
- Steven Moreira – Columbus – 2021–
- Vincent Nogueira – Philadelphia – 2014–16
- Jason Pendant – New York Red Bulls – 2020–
- Damien Perrinelle – New York Red Bulls – 2014–17
- Jean-Baptiste Pierazzi – San Jose – 2014–15
- Laurent Robert – Toronto – 2008[b REU]
- Bacary Sagna – Montreal – 2018–19
- Saër Sène – New England, New York Red Bulls – 2012–14
- Mikaël Silvestre – Portland – 2013
- Clément Simonin – Toronto – 2015
- Florent Sinama Pongolle – Chicago – 2014[b REU]
- Diedie Traore – LA Galaxy – 2019–20
- Florian Valot – New York Red Bulls, Cincinnati – 2018–21
- Remi Walter – Kansas City – 2021–
- Guram Kashia – San Jose – 2018–20
- Valeri Qazaishvili – San Jose – 2017–20
- Stefan Aigner – Colorado – 2017–18
- Julian Büscher – D.C. United – 2016–17
- Rafael Czichos – Chicago – 2022–
- Arne Friedrich – Chicago – 2012
- Torsten Frings – Toronto – 2011–12
- Andreas Görlitz – San Jose – 2014
- Julian Gressel – Atlanta, D.C. United – 2017–
- Fabian Herbers – Philadelphia, Chicago – 2016–
- Kai Herdling – Philadelphia – 2012
- Florian Jungwirth – San Jose, Vancouver – 2017–
- Kevin Kratz – Atlanta – 2017–19
- Kenneth Kronholm – Chicago – 2019–20[b USA]
- Florian Lechner – New England – 2012
- Lothar Matthäus – MetroStars – 2000
- Hany Mukhtar – Nashville – 2020–
- Timo Pitter – Dallas – 2016
- Frank Rost – New York Red Bulls – 2011
- Marc Rzatkowski – New York Red Bulls – 2018–20
- Bastian Schweinsteiger – Chicago – 2017–19
- Amar Sejdić – Montréal, Atlanta United FC – 2019-
- Christian Tiffert – Seattle – 2012
- Mandi Urbas – Dallas – 2003
- Kai Wagner – Philadelphia – 2019–
- Gordon Wild – LA Galaxy – 2020
- Alexandros Tabakis – Atlanta – 2017
- Botond Baráth – Kansas City – 2019
- Dániel Gazdag – Philadelphia – 2021–
- Zoltán Hercegfalvi – Kansas City – 2009
- Krisztián Németh – Kansas City, New England, Columbus – 2015, 2017–20
- Nemanja Nikolić – Chicago – 2017–19[b SRB–YUG 1]
- Dániel Sallói – Kansas City – 2017–
- Szabolcs Schön – Dallas – 2021–
- Zoltán Stieber – D.C. United – 2017–19
- István Urbányi – San Jose – 1997–98
- Victor Pálsson – New York Red Bulls – 2012
- Kristinn Steindórsson – Columbus – 2015
- Guðmundur Þórarinsson – New York City FC – 2020–21
- Arnór Ingvi Traustason – New England – 2021–
- Thorleifur Úlfarsson – Houston – 2022–
- Orr Barouch – Chicago – 2011–12
- Omer Damari – New York Red Bulls – 2016
- Dedi Ben Dayan – Colorado – 2005–06
- Gadi Kinda – Kansas City – 2020–[b ETH]
- Guy Melamed – Colorado – 2005
- Nicola Caricola – MetroStars – 1996
- Gabriele Corbo – Montréal – 2022–
- Bernardo Corradi – Montreal – 2012
- Carlo Cudicini – LA Galaxy – 2013
- Marco Di Vaio – Montreal – 2012–14
- Marco Donadel – Montreal – 2015–18
- Roberto Donadoni – MetroStars – 1996–97
- Matteo Ferrari – Montreal – 2012–14[b ALG]
- Giuseppe Galderisi – New England, Tampa Bay – 1996–97
- Sebastian Giovinco – Toronto – 2015–18
- Matteo Mancosu – Montreal – 2016–18
- Vito Mannone – Minnesota – 2019
- José Mauri – Kansas City – 2021–[b ARG]
- Alessandro Nesta – Montreal – 2012–13
- Antonio Nocerino – Orlando – 2016–17
- Daniele Paponi – Montreal – 2013
- Andrea Pirlo – New York City FC – 2015–17
- Giuseppe Rossi – Salt Lake – 2020[b USA]
- Andrea Pisanu – Montreal – 2013
- Paolo Tornaghi – Chicago, Vancouver – 2012–13, 2016–17
- Walter Zenga – New England – 1997, 1999
- Raivis Hščanovičs – Toronto – 2010
- Nicolas Hasler – Toronto, Chicago, Kansas City – 2017–19
- Vytautas Andriuškevičius – Portland, D.C. United – 2016–18
- Edgaras Jankauskas – New England – 2009–10
- Maxime Chanot – New York City FC – 2016–[b FRA]
- Etienne Barbara – Vancouver – 2012
- Mersim Beskovic – MetroStars – 2001
- Branko Bošković – D.C. United – 2010–12[b SRB–YUG 1]
- Emrah Klimenta – LA Galaxy – 2018
- Nemanja Vuković – Columbus – 2012
- Alexander Büttner – New England – 2020
- Geoffrey Castillion – New England – 2014
- Nigel de Jong – LA Galaxy – 2016
- Siem de Jong – Cincinnati – 2020[b SUI]
- Michael de Leeuw – Chicago – 2016–18
- Raimo de Vries – Colorado – 1996
- Rachid El Khalifi – Salt Lake – 2009
- John Goossens – Chicago – 2016–18
- Edwin Gorter – New England, Miami Fusion – 1998–99
- Richard Goulooze – New England – 1998–99
- Danny Hoesen – San Jose, Austin – 2017–
- Collins John – Chicago – 2010[b LBR]
- Johan Kappelhof – Chicago – 2016–
- Danny Koevermans – Toronto – 2011–13
- Kai Koreniuk – LA Galaxy – 2020[b USA][c USA U17]
- Jürgen Locadia – Cincinnati – 2020–21
- Sherjill MacDonald – Chicago – 2012–13
- Nick Marsman – Inter Miami – 2021–
- Maarten Paes – Dallas – 2022–
- Nigel Robertha – D.C. United – 2021–
- Victor Sikora – Dallas – 2008
- Nick Soolsma – Toronto – 2011–12
- Pele van Anholt – LA Galaxy – 2017–18
- Dave van den Bergh – Kansas City, New York Red Bulls, Dallas – 2006–09
- Silvester van der Water – Orlando – 2021–
- Maikel van der Werff – Cincinnati – 2019–20
- Gregory van der Wiel – Toronto – 2018
- Kenneth Vermeer – Los Angeles FC, Cincinnati – 2020–
- Ronald Waterreus – New York Red Bulls – 2007
- Giliano Wijnaldum – Philadelphia – 2017
- Vito Wormgoor – Columbus – 2020–21
- Steve Morrow – Dallas – 2002–03
- Martin Paterson – Orlando – 2015[b ENG]
- Jonny Steele – Salt Lake, New York Red Bulls – 2012–14
- Mark Williams – Columbus – 2003[b ENG]
- Øyvind Alseth – Toronto – 2017
- Jo Inge Berget – New York City FC – 2018
- Vadim Demidov – Minnesota – 2017[b LVA–URS]
- Adama Diomande – Los Angeles FC – 2018–20
- Magnus Wolff Eikrem – Seattle – 2018
- Ruben Gabrielsen – Austin – 2022–
- Jakob Glesnes – Philadelphia – 2020–
- Fredrik Gulbrandsen – New York Red Bulls – 2017
- Eirik Johansen – New York City FC – 2015–17
- Bjørn Maars Johnsen – Montreal – 2021–[b USA]
- Pa-Modou Kah – Portland, Vancouver – 2013–16[b GMB]
- Muhamed Keita – New York Red Bulls – 2017–18[b GMB]
- Ola Kamara – Columbus, LA Galaxy, D.C. United – 2016–
- Nicolai Næss – Columbus – 2016–17
- Jørgen Skjelvik – LA Galaxy – 2018–19
- Jan Gunnar Solli – New York Red Bulls – 2011–12
- Adam Buksa – New England – 2020–
- Przemysław Frankowski – Chicago – 2019–21
- Tomasz Frankowski – Chicago – 2008
- Andrzej Juskowiak – MetroStars – 2003
- Patryk Klimala – New York Red Bulls – 2021–
- Roman Kosecki – Chicago – 1998–99
- Wojtek Krakowiak – San Jose, Tampa Bay – 2000–01
- Krzysztof Król – Chicago, Montreal – 2010, 2014
- Jarosław Niezgoda – Portland – 2020–
- Piotr Nowak – Chicago – 1998–2002
- Damien Perquis – Toronto – 2015–16[b FRA][c FRA U21]
- Jerzy Podbrożny – Chicago – 1998–99
- Kacper Przybyłko – Philadelphia, Chicago – 2019–[b GER]
- Miroslaw Rzepa – Columbus – 2000
- Przemysław Tytoń – Cincinnati – 2019–21
- Konrad Warzycha – Kansas City, Columbus – 2012–13
- Robert Warzycha – Columbus – 1996–2002
- Jacek Ziober – Tampa Bay – 1998
- Janio Bikel – Vancouver – 2020–21[b GNB]
- Nuno André Coelho – Kansas City – 2016
- Yannick Djaló – San Jose – 2014[b GNB]
- José Gonçalves – New England – 2013–16
- André Horta – Los Angeles FC – 2018–19
- Luís Martins – Kansas City – 2019–21
- João Meira – Chicago – 2016–17
- João Moutinho – Los Angeles FC, Orlando – 2018–
- Nani – Orlando – 2019–21
- João Pedro – LA Galaxy – 2017–18
- Rafael Ramos – Orlando, Chicago – 2015–18
- Paulo Renato – San Jose – 2015
- Pedro Santos – Columbus – 2017–
- Carlos Semedo – New England – 2002
- David Viana – Salt Lake – 2012[b FRA]
- Abel Xavier – LA Galaxy – 2007–08[b MOZ]
- Richie Baker – New England – 2004
- Bryan Byrne – New England – 2007
- Kevin Doyle – Colorado – 2015–17
- Danny Earls – Colorado – 2010–11
- Caleb Folan – Colorado – 2011[b ENG]
- Jon Gallagher – Atlanta, Austin – 2020–
- Ian Hennessy – MetroStars – 1996
- Robbie Keane – LA Galaxy – 2011–16
- Paul Keegan – New England – 1996–2000
- Joe Mason – Colorado – 2018[b ENG]
- Chris McCann – Atlanta, D.C. United – 2017–19
- Jake Mulraney – Atlanta – 2020–
- Andy O'Brien – Vancouver – 2012–14[b ENG][c ENG U18]
- Ronnie O'Brien – Dallas, Toronto, San Jose – 2002–08
- Darren O'Dea – Toronto – 2012–13
- Sean St Ledger – Orlando, Colorado – 2015[b ENG]
- Derrick Williams – LA Galaxy – 2021–[b GER]
- Deian Boldor – Montreal – 2017
- Andreas Ivan – New York Red Bulls – 2018–19[c GER U19]
- Răzvan Cociș – Chicago – 2014–16
- Alexandru Mățan – Columbus – 2021–
- Alexandru Mitriță – New York City FC – 2019–20
- Alex Zotincă – Kansas City, Chivas USA – 2003–08, 2010
- Rod Dyachenko – D.C. United – 2006–08
- Sergei Raad – Kansas City – 2006
- Igor Simutenkov – Kansas City – 2002–04
- Maxim Usanov – Toronto – 2010
- Kris Boyd – Portland – 2012
- Chris Cadden – Columbus – 2020
- Steven Caldwell – Toronto – 2013–15
- Peter Canero – New York Red Bulls – 2006
- Jamie Clark – San Jose – 1999–2000
- Paul Dalglish – Houston – 2006–07
- Kenny Deuchar – Salt Lake – 2008
- Stuart Findlay – Philadelphia – 2021–
- Tony Gallacher – Toronto – 2020
- Ryan Gauld – Vancouver – 2021–
- Richard Gough – Kansas City, San Jose – 1997–98[b SWE]
- Mo Johnston – Kansas City – 1996–2001
- Gary Mackay-Steven – New York City FC – 2019–20
- Calum Mallace – Montreal, Los Angeles FC – 2012–18
- Shaun Maloney – Chicago – 2015[b MYS]
- Tam McManus – Colorado – 2008
- Kenny Miller – Vancouver – 2012–14
- Adam Moffat – Columbus, Portland, Houston, Seattle, Dallas – 2007–14
- Lewis Morgan – Inter Miami, New York Red Bulls – 2020–
- Sam Nicholson – Minnesota, Colorado – 2017–20
- Barry Robson – Vancouver – 2012
- Johnny Russell – Kansas City – 2018–
- Jamie Smith – Colorado – 2009–13
- Steven Smith – Portland – 2012
- Kevin Souter – Kansas City – 2009–10
- John Spencer – Colorado – 2001–04
- Danny Wilson – Colorado – 2018–
- Saša Ćurčić – MetroStars – 1999
- Dejan Joveljić – LA Galaxy – 2021–[b BIH]
- Aleksandar Katai – Chicago, LA Galaxy – 2018–20
- Miloš Kocić – D.C. United, Toronto, Portland – 2009–13
- Alen Kozić – Miami Fusion – 1998–99
- Neven Marković – Kansas City – 2012[b BIH–YUG]
- Veljko Paunović – Philadelphia – 2011[b MKD–YUG]
- Marko Perović – New England – 2010–11
- Ivan Polic – LA Galaxy – 2000
- Vuk Rašović – Kansas City – 2004[b FRG]
- Bratislav Ristić – Chicago – 2010–11
- Dejan Rusmir – Columbus – 2011
- Bojan Stepanović – Chivas USA – 2009
- Alen Stevanović – Toronto – 2011[b SUI]
- Luka Stojanović – Chicago – 2020–21
- Miloš Stojčev – Kansas City – 2011
- Ilija Stolica – New England – 2010–11
- Ranko Veselinović – Vancouver – 2020–
- Bojan Vučković – New England – 1996
- Ján Greguš – Minnesota, San Jose – 2019–
- Adam Nemec – New York City FC – 2015
- Ľubomír Reiter – Chicago – 2005
- Albert Rusnák – Salt Lake, Seattle – 2017–[b CZE]
- Boris Sekulić – Chicago – 2020–[b SRB–YUG 1]
- Robert Berić – Chicago – 2020–21
- Antonio Delamea Mlinar – New England – 2017–20
- Aljaž Ivačič – Portland – 2020–
- Žan Kolmanič – Austin – 2021–
- Aljaž Struna – Houston, Montreal – 2019–21
- Andraž Struna – New York City FC – 2017
- Agus – Houston – 2016
- Ager Aketxe – Toronto – 2018
- Pablo Álvarez Núñez – New York City FC – 2015[c GAL]
- Eloi Amagat – New York City FC – 2018
- Angeliño – New York City FC – 2015
- Armando – New York Red Bulls – 2014
- Jon Bakero – Chicago, Toronto – 2018
- Miguel Berry – Columbus – 2021–
- Ruben Bover – New York Red Bulls – 2013–14
- Albert Celades – New York Red Bulls – 2009
- Christian – D.C. United – 2014
- Jon Erice – Vancouver – 2019
- Andreu Fontàs – Kansas City – 2018–[c CAT]
- Dani Fragoso – Chivas USA – 2014
- Carles Gil – New England – 2019–
- Ilie – Kansas City, Los Angeles FC – 2017–
- Andoni Iraola – New York City FC – 2015–16[c EUS]
- Jesús Jiménez – Toronto – 2022–
- José Mari – Colorado – 2014
- Aitor Karanka – Colorado – 2006[c EUS]
- Koke – Houston – 2011
- Bojan Krkić – Montreal – 2019–20[c CAT]
- Gorka Larrea – Montreal – 2014
- Cristian Lobato – Kansas City – 2017–18
- Ignacio Maganto – LA Galaxy – 2015
- José Martínez – Dallas – 2021–
- David Mateos – Orlando – 2015–16
- Álvaro Medrán – Chicago – 2020–21
- Mista – Toronto – 2010
- José Luis Morales – New England – 2000
- Alfredo Ortuño – Salt Lake – 2018
- Javier Pérez – Los Angeles FC – 2019
- Víctor Pérez – Chicago – 2015
- Alejandro Pozuelo – Toronto – 2019–
- Jordi Quintillà – Kansas City – 2015–16
- Álvaro Rey – Toronto, Columbus – 2013–14
- David Rocha – Houston – 2016
- Raúl Rodríguez – Houston – 2015–16[c CAT]
- Víctor Rodríguez – Seattle – 2017–19[c CAT]
- Oriol Rosell – Kansas City, Orlando – 2012–14, 2018–[c CAT]
- Toni – Kansas City – 2014
- Carlos Varela – D.C. United – 2010
- Víctor Vázquez – Toronto, LA Galaxy – 2017–18, 2021–
- David Villa – New York City FC – 2015–18
- John Alvbåge – Minnesota – 2017
- Johan Blomberg – Colorado – 2018–19
- Jan Eriksson – Tampa Bay – 1998–99
- Magnus Eriksson – San Jose – 2018–20
- Erik Friberg – Seattle – 2011, 2015–16
- Markus Holgersson – New York Red Bulls – 2012–13
- Zlatan Ibrahimović – LA Galaxy – 2018–19
- Stefan Ishizaki – LA Galaxy – 2014–15
- Robin Jansson – Orlando – 2019–
- Adam Johansson – Seattle – 2012
- Anders Limpar – Colorado – 1999–2000
- Freddie Ljungberg – Seattle, Chicago – 2009–10
- Adam Lundqvist – Houston – 2018–
- Christopher McVey – Inter Miami – 2022–
- Tom Pettersson – Cincinnati – 2020–21
- Joel Qwiberg – San Jose – 2018[b COL]
- Thomas Ravelli – Tampa Bay – 1998
- Björn Runström – New England – 2012
- Axel Sjöberg – Colorado, D.C. United – 2015–20
- Gustav Svensson – Seattle – 2017–20
- Anton Tinnerholm – New York City FC – 2018–
- Christian Wilhelmsson – LA Galaxy – 2012
- François Affolter – San Jose – 2017–19
- Tranquillo Barnetta – Philadelphia – 2015–16
- Leonardo Bertone – Cincinnati – 2019
- Davide Chiumiento – Vancouver – 2011–12[c ITA U21]
- Blerim Džemaili – Montreal – 2017[b MKD–YUG]
- Jonas Elmer – Toronto – 2013
- Innocent Emeghara – San Jose – 2015–16[b NGA]
- Stefan Frei – Toronto, Seattle – 2009–11, 2013–
- Dennis Iapichino – Montreal, D.C. United – 2012–13
- Blaise Nkufo – Seattle – 2010[b ZAI]
- Alain Rochat – Vancouver, D.C. United – 2011–13[b CAN]
- Philippe Senderos – Houston – 2017–18
- Xherdan Shaqiri – Chicago – 2022–
- Alain Sutter – Dallas – 1997–98
- Scott Sutter – Orlando, Vancouver – 2017–19[b ENG]
- Jérôme Thiesson – Minnesota – 2017–18
- Raphaël Wicky – Chivas USA – 2008
- Adrian Winter – Orlando – 2015–16
- Reto Ziegler – Dallas – 2018–20
- Sercan Güvenışık – San Jose – 2012
- Sergi Daniv – Dallas, Chicago – 1999–2002
- Ihor Dotsenko – Kansas City – 2000
- Aleksey Korol – Dallas, Chicago – 2000–02
- Dema Kovalenko – Chicago, D.C. United, New York Red Bulls, Salt Lake, LA Galaxy – 1999–2010
- Yuri Lavrinenko – Chicago – 2000
- Andy Dorman – New England – 2004–07, 2013–15[b ENG]
- Robert Earnshaw – Toronto, Chicago, Vancouver – 2013–15[b ZMB]
- Adam Henley – Salt Lake – 2018[b USA]
- Carl Robinson – Toronto, New York Red Bulls – 2007–11
North and Central America, Caribbean (CONCACAF)
- Tony Rocha – Orlando, New York City FC – 2016–21[b USA]
- Michael Salazar – Montreal, Houston – 2016–17, 2019–20[b USA]
- Freddy Hall – Toronto – 2012
- Reggie Lambe – Toronto – 2012–13
- Khano Smith – New England, New York Red Bulls – 2005–10
- Jairo Arrieta – Columbus, D.C. United – 2012–15
- Gabriel Badilla – New England – 2008
- Christian Bolaños – Vancouver – 2016–17
- Jonathan Bolaños – Chicago – 2003
- Pablo Brenes – MetroStars – 2004
- Keyner Brown – Houston – 2016
- Francisco Calvo – Minnesota, Chicago, San Jose – 2017–
- Diego Campos – Chicago – 2018–19
- Julio Cascante – Portland, Austin – 2018–
- Dennis Castillo – Colorado – 2016–17
- Pablo Chinchilla – LA Galaxy – 2005
- Allan Cruz – Cincinnati – 2019–
- Darío Delgado – Chivas USA – 2010
- Luis Díaz – Columbus – 2019–
- Argenis Fernández – New England – 2008
- Waylon Francis – Columbus, Seattle – 2014–21
- Giancarlo González – Columbus, LA Galaxy – 2014, 2019–20
- Leonardo González – Seattle – 2009–15
- David Guzmán – Portland, Columbus – 2017–19
- Denis Hamlett – Colorado – 1996
- Andy Herron – Chicago, Columbus – 2004–08
- Carlos Johnson – New York Red Bulls – 2009
- Ariel Lassiter – LA Galaxy, Houston, Inter Miami – 2015–18, 2020–[c USA U23]
- Randall Leal – Nashville – 2020–
- José Leitón – Minnesota – 2017
- Porfirio López – Philadelphia – 2012
- Marvin Loría – Portland – 2019–
- José Macotelo – Chivas USA – 2010
- Josué Martínez – Philadelphia, New York Red Bulls – 2012–13
- Rónald Matarrita – New York City FC, Cincinnati – 2016–
- Roy Miller – New York Red Bulls, Portland – 2010–15, 2017–18
- Joseph Mora – D.C. United, Charlotte – 2018–
- Kurt Morsink – Kansas City, D.C. United – 2007–11[b USA]
- Roy Myers – MetroStars, LA Galaxy – 1999–2001
- David Myrie – Philadelphia – 2010
- José Guillermo Ortiz – D.C. United – 2017
- Álvaro Saborío – Salt Lake, D.C. United – 2010–16
- Álvaro Sánchez – Dallas – 2009
- Erick Scott – Columbus – 2004
- Gonzalo Segares – Chicago – 2005–14
- Ulises Segura – D.C. United – 2018–20
- Alejandro Sequeira – Tampa Bay, San Jose – 1998
- Douglas Sequeira – Chivas USA, Salt Lake – 2005–06
- Jordan Smith – Vancouver – 2015–16
- Mauricio Solís – San Jose – 1999–2000
- Jafet Soto – Salt Lake – 2006
- William Sunsing – New England – 2000–01
- Daniel Torres – Columbus, Salt Lake, Dallas – 2001–03, 2006–07, 2009
- Michael Umaña – LA Galaxy, Chivas USA – 2005, 2010–11
- Marco Ureña – San Jose, Los Angeles FC – 2017–18
- Olman Vargas – Columbus – 2012
- Johan Venegas – Montreal, Minnesota – 2015–17
- Rodney Wallace – D.C. United, Portland, New York City FC, Kansas City – 2009–15, 2017–19
- Paulo Wanchope – Chicago – 2007
- Kendall Waston – Vancouver, Cincinnati – 2014–20
- Mauricio Wright – San Jose, New England – 1999–2001
- Osvaldo Alonso – Seattle, Minnesota, Atlanta– 2009–
- Yordany Álvarez – Salt Lake – 2011–13
- Maikel Chang – Salt Lake – 2020–
- Jorge Corrales – Chicago, Montreal – 2018–20
- Alberto Delgado – Colorado – 2004
- Maykel Galindo – Chivas USA, Dallas – 2007–11
- Rey Ángel Martínez – Colorado – 2004
- Eduardo Sebrango – Montreal – 2012
- Javier Martina – Toronto – 2011[c NED U20][c NED U19]
- Eloy Room – Columbus – 2019–[b NED][c NED U20]
- Edison Azcona – Inter Miami – 2021–
- Jaime Alas – San Jose – 2013
- Arturo Álvarez – San Jose, Dallas, Salt Lake, Chicago, Houston – 2003–11, 2016–18[b USA][c USA U23][c USA U20][c USA U18][c USA U17]
- Junior Burgos – Toronto – 2012
- Eric Calvillo – San Jose – 2018–20[b USA][c USA U19][c USA U17]
- Christian Castillo – D.C. United – 2010
- Darwin Cerén – Orlando, San Jose, Houston – 2015–
- Ronald Cerritos – San Jose, Dallas, D.C. United, Houston – 1997–2006
- Mauricio Cienfuegos – LA Galaxy – 1996–2003
- Raúl Díaz Arce – D.C. United, New England, San Jose, Tampa Bay, Colorado – 1996–2001
- Andrés Flores – Portland – 2018–20
- Marvin Iraheta – Chivas USA – 2013
- Julio Martínez – Chicago – 2010
- Gerson Mayen – Chivas USA – 2009–11[b USA][c USA U20]
- Amando Moreno – New York Red Bulls, Chicago – 2013, 2019[b USA][c USA U20][c USA U18]
- Alfredo Pacheco – New York Red Bulls – 2009
- Joshua Pérez – Los Angeles FC – 2018–19[b USA][c USA U23][c USA U20][c USA U19][c USA U17][c USA U15]
- Steve Purdy – Dallas, Portland, Chivas USA – 2009, 2011–13[b USA][c USA U23][c USA U20][c USA U17]
- Marvin Quijano – LA Galaxy, Colorado – 1999–2002
- Eliseo Quintanilla – D.C. United – 2002–03
- Jorge Rodríguez – Dallas – 1997–2002
- Alex Roldan – Seattle – 2018–[b USA]
- Osael Romero – Chivas USA – 2010
- Tomas Romero – Los Angeles FC – 2021–[b USA]
- Ramón Sánchez – San Jose – 2009–10
- Deris Umanzor – Chicago – 2010
- Eriq Zavaleta – Seattle, Chivas USA, Toronto – 2013–[b USA][c USA U17]
- Rodolfo Zelaya – Los Angeles FC – 2019
- Shalrie Joseph – New England, Chivas USA, Seattle – 2003–13
- Craig Rocastle – Kansas City – 2010–11[b ENG]
- Stéphane Auvray – Kansas City, New York Red Bulls – 2010–11
- Miguel Comminges – Colorado – 2011
- Eddy Viator – Toronto – 2011[b FRA]
- Ronald Zubar – New York Red Bulls – 2015–16[c FRA U21]
- Gustavo Cabrera – Salt Lake – 2005
- Freddy García – Columbus – 2002–03
- Moises Hernandez – Dallas – 2014–15[b USA][c USA U20]
- Martín Machón – LA Galaxy, Miami Fusion – 1997–98, 2000
- Arquimides Ordonez – Cincinnati – 2021–[b USA]
- Marco Pappa – Chicago, Seattle, Colorado – 2008–12, 2014–16
- Guillermo Ramírez – LA Galaxy – 2005
- Jorge Rodas – San Jose – 1996
- Mario Rodríguez – Columbus – 2005
- Carlos Ruiz – LA Galaxy, Dallas, Toronto, Philadelphia, D.C. United – 2002–08, 2011, 2013, 2016
- Rodrigo Saravia – Columbus – 2016
- Willie Sims – New England – 2006
- Jonathan Top – Dallas – 2012[b USA][c USA U20]
- Elías Vásquez – Salt Lake – 2015
- Warren Creavalle – Houston, Toronto, Philadelphia – 2012–20[b USA][c USA U20]
- Gregory Richardson – Colorado – 2009
- J. P. Rodrigues – D.C. United – 2010[b USA]
- Emery Welshman – Toronto – 2013[b CAN]
- Jean Alexandre – Salt Lake, San Jose – 2009–12
- Alexandre Boucicaut – Chicago – 2004
- Steward Ceus – Colorado – 2012–13[b USA]
- Derrick Etienne – New York Red Bulls, Cincinnati, Columbus – 2016–[b USA]
- Lesly Fellinga – Toronto – 2009[c NED U15]
- Zachary Herivaux – New England – 2016, 2018[b JPN]
- Andrew Jean-Baptiste – Portland, Chivas USA – 2012–14[b USA][c USA U18]
- Mechack Jérôme – Kansas City – 2013–14
- Peterson Joseph – Kansas City – 2011–13
- Jerrod Laventure – New York Red Bulls – 2006–07[b USA]
- James Marcelin – Portland, Dallas – 2011–12
- Josué Mayard – Dallas – 2001–02[b CAN]
- Soni Mustivar – Kansas City – 2015–17[b FRA][c FRA U20]
- Fabrice Noël – Colorado – 2005–06
- Peguero Jean Philippe – Colorado, New York Red Bulls, San Jose – 2004–06, 2008
- Brian Sylvestre – Philadelphia – 2015[b USA][c USA U20]
- Patrick Tardieu – New England – 1996
- Sebastien Vorbe – LA Galaxy – 2000
- Bryan Acosta – Dallas, Colorado – 2019–
- Danilo Acosta – Salt Lake, Orlando, LA Galaxy– 2017–19, 2021[c USA U20]
- Éver Alvarado – Kansas City – 2016
- Kervin Arriaga – Minnesota – 2022–
- Brayan Beckeles – Nashville – 2020
- Jerry Bengtson – New England – 2012–14
- Víctor Bernárdez – San Jose – 2012–17
- Samuel Caballero – Chicago – 2005
- Mauricio Castro – New England – 2008–09
- Marvin Chávez – Dallas, San Jose, Colorado, Chivas USA – 2009–14
- Michaell Chirinos – Vancouver – 2019
- Jorge Claros – Kansas City – 2014
- Carlo Costly – Houston – 2011
- Arnold Cruz – D.C. United, San Jose – 1997–98
- Alberth Elis – Houston – 2017–20
- José Escalante – Houston – 2016–17
- Roger Espinoza – Kansas City – 2008–12, 2015–
- Maynor Figueroa – Colorado, Dallas, Houston – 2015–21
- Deybi Flores – Vancouver – 2015–16
- Boniek García – Houston – 2012–21
- Luis Garrido – Houston – 2014–15
- Iván Guerrero – Chicago, San Jose, D.C. United – 2005–08
- Amado Guevara – New York Red Bulls, Chivas USA, Toronto – 2003–09
- Johnny Leverón – Vancouver – 2013–14
- Alexander López – Houston – 2013–15
- Luis López Fernández – Los Angeles FC – 2018
- Douglas Martínez – Salt Lake – 2019–21
- Mario Martínez – Seattle – 2012–13
- Saúl Martínez – Miami Fusion – 1999
- Walter Martínez – San Jose – 2013
- Andy Najar – D.C. United, Los Angeles FC – 2010–12, 2020–
- Ramón Núñez – Dallas, Chivas USA – 2004–07, 2013
- Carlos Pavón – LA Galaxy – 2007
- Alex Pineda Chacón – Miami Fusion, New England, LA Galaxy, Columbus – 2001–03
- Romell Quioto – Houston, Montreal – 2017–
- Milton Reyes – D.C. United, Dallas – 2002, 2004
- Bryan Róchez – Orlando – 2015
- Joseph Rosales – Minnesota – 2021–
- Hendry Thomas – Colorado, Dallas – 2012–14
- Nicholas Addlery – D.C. United – 2007
- Giles Barnes – Houston, Vancouver, Orlando – 2012–17[b ENG][c ENG U19]
- Andre Blake – Philadelphia – 2014–
- Neco Brett – Portland – 2016
- Brian Brown – Philadelphia – 2014
- Deshorn Brown – Colorado, D.C. United – 2013–15, 2017
- Javain Brown – Vancouver – 2021–
- Cory Burke – Philadelphia – 2018–
- Altimont Butler – San Jose, Columbus – 1996–97
- Sergio Campbell – Columbus – 2015
- Omar Cummings – Colorado, Houston – 2007–14
- Rashawn Dally – Cincinnati – 2019–20[b USA]
- Chris Dawes – Colorado – 2001
- Simon Dawkins – San Jose – 2011–12, 2016–17[b ENG]
- Stephen DeRoux – D.C. United – 2006–07
- Joey DeZart – Orlando – 2020–[b USA]
- Oniel Fisher – Seattle, D.C. United, LA Galaxy, Minnesota – 2015–
- Shaun Francis – Columbus, Chicago, San Jose, Montreal – 2010–17
- Brenton Griffiths – Colorado – 2013
- Winston Griffiths – MetroStars, LA Galaxy, New England – 2002
- Wolde Harris – Colorado, New England, Kansas City, Colorado – 1997–03, 2005
- Omar Holness – Salt Lake – 2016–17
- Jermaine Hue – Kansas City – 2005–06
- Jason Johnson – Houston, Chicago – 2013–15
- Ryan Johnson – Salt Lake, Chicago, San Jose, Toronto, Portland – 2006, 2008–13
- Dane Kelly – D.C. United – 2018
- Kemar Lawrence – New York Red Bulls, Toronto – 2015–19, 2021–
- Damion Lowe – Inter Miami – 2022–
- Onandi Lowe – Kansas City – 2001
- Tyrone Marshall – Colorado, Miami Fusion, LA Galaxy, Toronto, Seattle – 1998–2012
- Darren Mattocks – Vancouver, Portland, D.C. United, Cincinnati – 2012–19
- Justin McMaster – Minnesota – 2021–[b USA]
- Lovel Palmer – Houston, Portland, Salt Lake, Chicago – 2010–15
- Demar Phillips – Salt Lake – 2015–18
- Alvas Powell – Portland, Cincinnati, Inter Miami, Philadelphia – 2013–
- Darryl Powell – Colorado – 2003–04[b ENG]
- Damani Ralph – Chicago – 2003–04
- Dane Richards – New York Red Bulls, Vancouver – 2007–12, 2015
- Donovan Ricketts – LA Galaxy, Montreal, Portland, Orlando – 2009–15
- Robert Scarlett – Salt Lake – 2005
- Michael Seaton – D.C. United – 2013–14
- Greg Simmonds – Miami Fusion – 2001
- Khari Stephenson – Kansas City, San Jose, Salt Lake – 2004–05, 2010–15
- Fabian Taylor – MetroStars – 2004
- Jermaine Taylor – Houston, Portland, Minnesota – 2011–17
- Roger Thomas – Miami Fusion – 1998
- Shavar Thomas – Dallas, Kansas City, Chivas USA, Philadelphia, Montreal – 2003–12
- Peter-Lee Vassell – Los Angeles FC – 2019
- Je-Vaughn Watson – Houston, Dallas, New England – 2011–17
- O'Brian White – Toronto, Seattle – 2009–11
- Andy Williams – Columbus, Miami Fusion, New England, MetroStars, Chicago, Salt Lake – 1998–2011[b CAN]
- Dicoy Williams – Toronto – 2011–12
- Romario Williams – Montreal, Atlanta, Columbus – 2015, 2018–19
- Paul Young – Columbus, Tampa Bay – 1996, 1998
- Craig Ziadie – D.C. United, MetroStars – 2001–04[b USA]
- Jordy Delem – Seattle – 2017–21
- Harry Novillo – Montreal – 2019[b FRA][c FRA U17][c FRA U19]
- Frédéric Piquionne – Portland – 2013–14[b NCL][c FRA][c FRA B]
- José Manuel Abundis – New England – 2006
- Miguel Aguilar – D.C. United – 2015–16
- Oswaldo Alanís – San Jose – 2020–21
- Tony Alfaro – Seattle, D.C. United – 2016–18, 2021–
- Cesar Alvarado – Tampa Bay – 1999
- Byron Alvarez – MetroStars – 2002
- Damián Álvarez – Dallas, New England – 1997–98
- Efraín Álvarez – LA Galaxy – 2019–[b USA][c USA U15]
- Uriel Antuna – LA Galaxy – 2019
- Julián Araujo – LA Galaxy – 2019–[b USA][c USA][c USA U23][c USA U20][c USA U19][c USA U18]
- Rafael Baca – San Jose – 2011–13
- Adolfo Bautista – Chivas USA – 2014
- Armando Begines – Chivas USA – 2005
- Cuauhtémoc Blanco – Chicago – 2007–09
- Omar Bravo – Kansas City – 2011
- Jorge Campos – LA Galaxy, Chicago – 1996–98
- Giovani Casillas – Chivas USA – 2013
- Jorge Castañeda – Colorado – 1997
- Nery Castillo – Chicago – 2010
- Héctor Cuadros – Chivas USA – 2005
- Jürgen Damm – Atlanta – 2020–21
- Duilio Davino – Dallas – 2008
- Antonio de la Torre – Colorado – 2004
- Mario de Luna – Chivas USA – 2013
- Giovani dos Santos – LA Galaxy – 2015–18
- Jonathan dos Santos – LA Galaxy – 2017–21
- Missael Espinoza – San Jose – 1996
- Rodolfo Espinoza – Chivas USA – 2010
- Marco Fabián – Philadelphia – 2019
- Carlos Fierro – San Jose – 2019–21
- Vicente Figueroa – San Jose, Kansas City – 1998–2000
- Guillermo Franco – Chicago – 2012[b ARG]
- Johnny García – Chivas USA – 2006
- Juan Pablo García – Chivas USA – 2005–06
- Sergio García – Chivas USA – 2005
- Aaron Guillen – Dallas – 2016–17
- Daniel Guzmán – San Jose – 1997
- Carlos Hermosillo – LA Galaxy – 1996–97
- Cristhian Hernández – Philadelphia – 2012
- Javier Hernández – LA Galaxy – 2020–
- José Hernández – Salt Lake – 2017–18
- Luis Hernández – LA Galaxy – 2000–01
- Diego Jiménez – New York Red Bulls – 2008
- Efraín Juárez – Vancouver – 2018
- Luis Ángel Landín – Houston – 2009–10
- Bryan Leyva – Dallas – 2010, 2012
- Eduardo Lillingston – Chivas USA – 2009
- Alfonso Loera – Chivas USA – 2005
- Aaron López – Chivas USA – 2005
- Javier Eduardo López – San Jose – 2021–
- Rubén Luna – Dallas – 2010–12
- Rafael Márquez – New York Red Bulls – 2010–12
- Antonio Martínez – Dallas, LA Galaxy, Chivas USA – 2000–03, 2005
- Édgar Mejía – Chivas USA – 2013
- Raúl Mendiola – LA Galaxy – 2014, 2016–17
- Francisco Mendoza – Chivas USA – 2005–08, 2011
- Jesús Morales – Chivas USA – 2006
- David Ochoa – Salt Lake – 2020–[b USA][c USA U23][c USA U20][c USA U18]
- Jesús Ochoa – LA Galaxy, Chivas USA – 2002–03, 2005
- Daniel Osorno – Colorado – 2007
- Jesús Padilla – Chivas USA – 2009–10[b USA]
- Francisco Palencia – Chivas USA – 2005–06
- Pável Pardo – Chicago – 2011–12
- David Patiño – Colorado – 1997
- Jonathan Perez – LA Galaxy – 2021–[b USA][c USA U16]
- Gonzalo Pineda – Seattle – 2014–15
- Rodolfo Pizarro – Inter Miami – 2020–21
- Martín Ponce – Chivas USA – 2013
- Alan Pulido – Kansas City – 2020–
- Ramón Ramírez – Chivas USA – 2005
- José Retiz – LA Galaxy, Columbus – 2003, 2006
- Daniel Ríos – Nashville, Charlotte – 2020–
- José Manuel Rivera – Chivas USA – 2013
- Alberto Rizo – Colorado – 2003
- Edmundo Rodriguez – MetroStars, Kansas City – 1996–97
- Isaac Romo – Chivas USA – 2005
- Carlos Salcedo – Salt Lake, Toronto – 2013–14, 2022–
- Hugo Sánchez – Dallas – 1996
- Richard Sánchez – Chicago, Kansas City – 2017–18, 2020[b USA]
- Pablo Sisniega – Los Angeles FC, Charlotte – 2019–
- Erasmo Solórzano – Chivas USA – 2007
- Claudio Suárez – Chivas USA – 2006–09
- Erick Torres – Chivas USA, Houston, Atlanta – 2013–17, 2020–21
- Mariano Trujillo – Chivas USA – 2009–11
- Víctor Ulloa – Dallas, Cincinnati, Inter Miami – 2011, 2014–
- Francisco Uribe – San Jose – 1998
- Josecarlos Van Rankin – Portland – 2021–
- Carlos Vela – Los Angeles FC – 2018–
- Joaquín Velázquez – Chivas USA – 2013
- Adrian Zendejas – Kansas City – 2019[b USA]
- Alex Zendejas – Dallas – 2015[c USA U17][c USA U15]
- Martín Zúñiga – Chivas USA – 2005
- Roberto Brown – Colorado – 2007
- Omar Browne – Montreal – 2019
- Miguel Camargo – New York City FC – 2017
- Adalberto Carrasquilla – Houston – 2021–
- Armando Cooper – Toronto – 2016–17
- Harold Cummings – San Jose – 2018–19
- Jorge Dely Valdés – Colorado – 1999–2000
- Fidel Escobar – New York Red Bulls – 2017–18
- Rolando Escobar – Dallas – 2015
- Aníbal Godoy – San Jose, Nashville – 2015–
- Gabriel Gómez – Philadelphia – 2012
- Carlos Harvey – LA Galaxy – 2020–
- Adolfo Machado – Houston – 2017–18
- Cristian Martínez – Columbus, Chicago – 2016–19
- Michael Amir Murillo – New York Red Bulls – 2017–19
- Roberto Nurse – Chivas USA – 2008[b MEX]
- Jaime Penedo – LA Galaxy – 2013–15
- Blas Pérez – Dallas, Vancouver – 2012–16
- Ricardo Phillips – New England – 2005
- Alberto Quintero – San Jose – 2016
- Carlos Rodríguez – Dallas – 2012
- Marcos Sánchez – D.C. United – 2013
- Tony Taylor – New England, New York City FC – 2014–16[b USA][c USA U23][c USA U20]
- Luis Tejada – Salt Lake – 2007
- Gabriel Torres – Colorado – 2013–15
- Román Torres – Seattle, Inter Miami – 2015–20
- Cristian Arrieta – Philadelphia – 2010[b USA]
- Shawn Barry – Salt Lake – 2018[b USA]
- Terry Boss – Seattle – 2010[b USA]
- Bill Gaudette – Columbus, LA Galaxy, New York Red Bulls – 2005–06, 2012[b USA]
- Jeremy Hall – New York Red Bulls, Portland, Dallas, Toronto, New England – 2009–15[b USA][c USA U18][c USA U17]
- Jason Hernandez – MetroStars, Chivas USA, San Jose, New York City FC, Toronto – 2005–18[b USA]
- Tom Lips – New England – 1996
- Chris Megaloudis – New York Red Bulls – 2008[b USA]
- Manolo Sanchez – New York Red Bulls – 2015[b USA]
- Josh Saunders – LA Galaxy, Salt Lake, New York City FC – 2008–13, 2015–16[b USA][c USA U23]
- Zarek Valentin – Chivas USA, Montreal, Portland, Houston – 2011–12, 2016–[b USA][c USA U23][c USA U20]
- Marco Vélez – Toronto – 2008–09
- Petter Villegas – MetroStars, D.C. United – 1996, 1999–2002[b ECU]
- Atiba Harris – Salt Lake, Chivas USA, Dallas, Vancouver, Colorado, San Jose – 2006–17
- Oalex Anderson – Seattle – 2016
- Ezra Hendrickson – MetroStars, LA Galaxy, Dallas, D.C. United, Chivas USA, Columbus – 1997–2008
- Roland Alberg – Philadelphia – 2016–17[b NED][c NED U20]
- Kelvin Leerdam – Seattle, Inter Miami, LA Galaxy – 2017–[c NED U21][c NED U19]
- Kevin Adams – Columbus – 2001
- Chris Birchall – LA Galaxy, Columbus – 2009–12[b ENG]
- Cordell Cato – Seattle, San Jose – 2012–17
- Daneil Cyrus – Kansas City, Chicago – 2011, 2015
- Keon Daniel – Philadelphia – 2011–13
- Aubrey David – Dallas – 2016[b GUY][c GUY]
- Craig Demmin – Tampa Bay – 2001
- Ancil Elcock – Columbus – 1997–2001
- Leslie Fitzpatrick – Salt Lake – 2005
- Kevan George – Columbus – 2012–15
- Gary Glasgow – Kansas City – 2000–02
- Cornell Glen – MetroStars, Columbus, Colorado, LA Galaxy, San Jose – 2004–06, 2009–10
- Brian Haynes – Dallas – 1996–2000
- Shaka Hislop – Dallas – 2006–07[b ENG][c ENG U21]
- Justin Hoyte – Cincinnati – 2019[b ENG][c ENG U21][c ENG U20][c ENG U19][c ENG U16]
- Julius James – Toronto, Houston, D.C. United, Columbus – 2008–12
- Avery John – New England, D.C. United – 2004–07, 2009
- Stern John – Columbus – 1998–99
- Joevin Jones – Chicago, Seattle, Inter Miami – 2015–17, 2019–
- Kenwyne Jones – Atlanta – 2017
- Darin Lewis – MetroStars – 2002
- Yohance Marshall – LA Galaxy – 2010
- Carlyle Mitchell – Vancouver – 2011–14
- Kevin Molino – Orlando, Minnesota, Columbus – 2015–
- Travis Mulraine – San Jose – 2000
- David Nakhid – New England – 1998
- Noah Powder – Salt Lake – 2021[b USA]
- Greg Ranjitsingh – Orlando, Minnesota – 2019–20[b CAN]
- Marlon Rojas – Salt Lake – 2005
- Collin Samuel – Toronto – 2007–08
- Scott Sealy – Kansas City, San Jose, Dallas – 2005–08, 2010–12
- Luke Singh – Toronto – 2021–[b CAN]
- Barry Swift – MetroStars – 1998
- Osei Telesford – Chicago – 2007
- Ryan Telfer – Toronto – 2018–19[b CAN]
- Keyeno Thomas – Colorado – 2000
- Sheldon Thomas – LA Galaxy – 2000
- Rick Titus – Colorado, Toronto – 2002, 2008[b CAN]
- Mickey Trotman – Dallas, Miami Fusion – 1998–99
- Nick Walker – Dallas – 2014
- Mekeil Williams – Colorado – 2016–17
- Evans Wise – Tampa Bay, New England – 1996–98
- Gavin Glinton – LA Galaxy, Dallas, San Jose – 2002–03, 2006–08
South America (CONMEBOL)
- Luciano Abecasis – San Jose – 2021
- Ramón Ábila – Minnesota, D.C. United – 2021
- Luciano Acosta – D.C. United, Cincinnati – 2016–19, 2021–
- Ignacio Aliseda – Chicago – 2020–21
- Favio Álvarez – LA Galaxy – 2019
- Emiliano Amor – Kansas City – 2018
- Adrián Arregui – Montreal – 2017
- Yamil Asad – Atlanta, D.C. United – 2017–18, 2020–21
- Mateo Bajamich – Houston – 2021
- Esequiel Barco – Atlanta – 2018–21
- Álvaro Barreal – Cincinnati – 2020–
- Leandro Barrera – Chivas USA, San Jose – 2014–15
- Guillermo Barros Schelotto – Columbus – 2007–10
- Claudio Benetti – Dallas – 1999–2000
- Hernán Bernardello – Montreal – 2013–14, 2016–17
- Claudio Bieler – Kansas City – 2013–14
- Sebastián Blanco – Portland – 2017–
- Emiliano Bonfigli – Salt Lake – 2012
- Martín Bonjour – Vancouver – 2012
- Gustavo Bou – New England – 2019–
- Claudio Bravo – Portland – 2021–
- Federico Bravo – New York City FC – 2016
- Víctor Cabrera – Montreal, Houston – 2015–20
- Franco Caraccio – Houston – 2008
- Milton Caraglio – New England – 2011
- Julián Carranza – Inter Miami, Philadelphia – 2020–
- Marcelo Carrera – Columbus – 1996–98
- Valentín Castellanos – New York City FC – 2018–
- Emanuel Cecchini – Seattle – 2019
- Ezequiel Cirigliano – Dallas – 2015
- Eloy Colombano – Kansas City – 2007–08
- Tomás Conechny – Portland – 2018–20
- Matías Córdoba – Salt Lake – 2008
- Facundo Coria – D.C. United – 2015
- Franco Coria – New England – 2011
- Eduardo Coudet – Philadelphia – 2010
- Emil Cuello – LA Galaxy – 2019–20
- Cristian da Silva – MetroStars – 1996–98
- Mauro Díaz – Dallas – 2013–18
- Facundo Diz – Colorado – 2009
- Eduardo Domínguez – LA Galaxy – 2008
- Matías Donnet – D.C. United – 2006
- Sebastián Driussi – Austin – 2021–
- Emiliano Dudar – D.C. United – 2012
- Facundo Erpen – D.C. United, Colorado – 2005–08
- Luis Miguel Escalada – Salt Lake – 2009
- Franco Escobar – Atlanta – 2018–20
- Fabián Espíndola – Salt Lake, New York Red Bulls, D.C. United – 2007–16
- Cristian Espinoza – San Jose – 2019–
- Darío Fabbro – Kansas City, New England – 2002–03
- Alejandro Farías – New England – 1997
- Brian Fernández – Portland – 2019
- Gastón Fernández – Portland – 2014–15
- Nicolás Figal – Inter Miami – 2020–21
- Lucio Filomeno – D.C. United – 2005–06
- Juan Forchetti – MetroStars – 2003
- Franco Fragapane – Minnesota – 2021–
- Alan Franco – Atlanta – 2021–
- Nicolás Gaitán – Chicago – 2019
- Marcelo Gallardo – D.C. United – 2008
- Braian Galván – Colorado – 2020–
- José Galván – MetroStars – 2003
- Sergio Galván Rey – MetroStars – 2004–05
- Walter García – New York Red Bulls – 2009
- Érik Godoy – Vancouver – 2019–
- Christian Gómez – D.C. United, Colorado – 2004–09
- Nelson González – Salt Lake – 2010–11
- Leandro González Pírez – Atlanta, Inter Miami – 2017–21
- Mario Gori – D.C. United, Miami Fusion, New England, Columbus – 1996–2000
- Hernán Grana – Columbus, Dallas – 2015, 2017
- Sebastián Grazzini – Chicago – 2011–12
- Guillermo Hauche – New England – 2018
- Nicolás Hernández – Colorado, Columbus – 2006–08
- Marcelo Herrera – Miami Fusion – 1998
- Federico Higuaín – Columbus, D.C. United, Inter Miami – 2012–21
- Gonzalo Higuaín – Inter Miami – 2020–[b FRA]
- Santiago Hirsig – Kansas City – 2009–10
- Franco Ibarra – Atlanta – 2021–
- Andrés Imperiale – San Jose – 2016–17
- Emiliano Insúa – LA Galaxy – 2020
- Ricardo Iribarren – Columbus, Dallas – 1996, 1998, 2000
- Sebastián Jaime – Salt Lake – 2014–15
- Lucas Janson – Toronto – 2018
- Agustin Jara – Dallas – 2016
- Franco Jara – Dallas – 2020–
- Leonardo Jara – D.C. United – 2019
- Matías Laba – Toronto, Vancouver – 2013–17
- Carlos Ledesma – MetroStars – 1998
- Emmanuel Ledesma – Cincinnati – 2019
- Claudio López – Kansas City, Colorado – 2008–10
- Lisandro López – Atlanta – 2021
- Miguel López – LA Galaxy – 2011
- Emanuel Maciel – Montreal – 2020–21
- Cristian Maidana – Philadelphia, Houston – 2014–16
- Matias Mantilla – Salt Lake – 2007–08
- Carlos Marinelli – Kansas City – 2007–08
- Diego Martínez – New York City FC – 2016
- Pity Martínez – Atlanta – 2019–20
- Juan Manuel Martínez – Salt Lake – 2015–16
- Tomás Martínez – Houston – 2017–20
- Emmanuel Mas – Orlando – 2021
- Lucas Melano – Portland – 2015–16
- Jonathan Menéndez – Salt Lake – 2021–
- Fernando Meza – Atlanta – 2020
- Sergio Miguez – Columbus – 1997
- Mariano Miño – Toronto – 2018
- Leonel Miranda – Houston – 2015–16
- Marcos Mondaini – Chivas USA – 2011
- Javier Morales – Salt Lake, Dallas – 2007–17
- Maximiliano Moralez – New York City FC – 2017–
- Marcelino Moreno – Atlanta – 2020–
- Federico Navarro – Chicago – 2021–
- Beto Naveda – New England – 1996–97
- Franco Niell – D.C. United – 2008
- Lucas Ontivero – Montreal – 2016
- Christian Ortiz – Charlotte – 2022–
- Rodrigo Pacheco – Los Angeles FC – 2018
- Gino Padula – Columbus – 2008–10
- Norberto Paparatto – Portland – 2014–15
- Cristian Pavón – LA Galaxy – 2019–20
- Daniel Peinado – Dallas – 1997
- Matías Pellegrini – Inter Miami – 2020
- Agustín Pelletieri – Chivas USA – 2014
- Gonzalo Peralta – D.C. United – 2008
- Matías Pérez García – San Jose, Orlando – 2014–17
- Ignacio Piatti – Montreal – 2014–19
- Pablo Piatti – Toronto – 2020
- Juan Pietravallo – New York Red Bulls – 2008–09
- Lucas Pittinari – Colorado – 2015
- Tomás Pochettino – Austin – 2021
- Facundo Quignon – Dallas – 2021–
- Juan Ramírez – Colorado – 2015
- Eric Remedi – Atlanta, San Jose – 2018–
- Emanuel Reynoso – Minnesota – 2020–
- Pablo Ricchetti – Dallas – 2007–09
- Andrés Ríos – San Jose – 2019–21
- Martín Rivero – Colorado, Chivas USA – 2012–14
- Javier Robles – San Jose – 2010
- Lucas Rodríguez – D.C. United – 2019
- Andrés Romero – Montreal – 2013–15, 2017
- Mauro Rosales – Seattle, Chivas USA, Vancouver, Dallas – 2011–17
- Silvio Rudman – Columbus – 1997
- Pablo Ruíz – Salt Lake – 2017–18, 2020–
- Darío Sala – Dallas – 2005–10
- Matías Sánchez – Columbus – 2013
- Martin Šarić – Toronto – 2010
- Gastón Sauro – Columbus – 2015–16, 2018–19
- Rodrigo Schlegel – Orlando – 2020–
- Luis Solignac – Colorado, Chicago – 2015–18
- Diego Soñora – Dallas, MetroStars, D.C. United, Tampa Bay – 1996–99, 2001
- Santiago Sosa – Atlanta – 2021–
- Leonardo Squadrone – New England – 1997
- Joaquín Torres – Montreal – 2021–
- Maximiliano Urruti – Toronto, Portland, Dallas, Montreal, Houston, Austin FC – 2013–
- Milton Valenzuela – Columbus – 2018, 2020–21
- Diego Valeri – Portland – 2013–21
- Jorge Vázquez – New England – 2003
- Daniel Vega – San Jose – 2019–21
- Matías Vera – Houston – 2019–
- Gonzalo Verón – New York Red Bulls – 2015–17
- Pablo Vitti – Toronto – 2009
- Marco Etcheverry – D.C. United – 1996–2003
- José Carlos Fernández – New England – 2001
- Jefferson Gottardi – Tampa Bay – 1999
- Cristhian Machado – New England – 2018
- Bruno Miranda – D.C. United – 2017–18
- Jaime Moreno – D.C. United, MetroStars – 1996–2010
- Juan Manuel Peña – D.C. United – 2010
- Jairo Quinteros – Inter Miami – 2022–
- Mauricio Ramos – Tampa Bay, New England – 1998–2000
- Maurizio Rocha – Miami Fusion – 1999–2000
- Sergio Salas – D.C. United – 2000
- Berthy Suárez – D.C. United – 1996
- Joselito Vaca – Dallas, MetroStars – 2001–04
- Roland Vargas-Aguilera – Columbus, New England – 2000–01
- Adaílton – Chicago – 2015
- Adauto Neto – Dallas – 2002
- Alex – Chicago, Houston – 2012–17
- Alex Cazumba – LA Galaxy – 2010
- Alexandre Pato – Orlando – 2021–
- Álvaro Pires – LA Galaxy – 2008
- Anderson Conceição – Philadelphia – 2016
- André Rocha – Dallas – 2008–09
- Andre Shinyashiki – Colorado – 2019–
- Antônio Carlos – Orlando – 2020–
- Artur – Columbus – 2017–
- Auro Jr. – Toronto – 2018–21
- Branco – MetroStars – 1997
- Brenner – Cincinnati – 2021–
- Bressan – Dallas – 2019–21
- Bruno Guarda – Dallas – 2008–12
- Bruno Menezes – Chicago – 2007
- Caio Alexandre – Vancouver – 2021–
- Camilo Sanvezzo – Vancouver – 2011–13
- Carlos Miguel Coronel – Philadelphia, New York Red Bulls – 2019, 2021–
- Cássio – New England – 2005
- Catê – New England – 2001
- Danilo Silva – MetroStars, Los Angeles FC – 2005, 2018–20
- David Lopes – Chivas USA, LA Galaxy – 2011–12
- Dejair – Chivas USA – 2008
- Denílson – Dallas – 2007
- Diego Walsh – Columbus, Kansas City – 2003–05
- Douglas Costa – LA Galaxy – 2022–
- Edu – Colorado – 2012
- Eduardo – San Jose – 2010
- Erick – Dallas – 2013
- Everton Luiz – Salt Lake – 2019–
- Fabinho – Philadelphia – 2013–19
- Fábio – New York Red Bulls – 2021
- Felipe – Montreal, New York Red Bulls, Vancouver, D.C. United, Austin – 2012–
- Fernando Bob – Minnesota – 2018
- Fred – D.C. United, Philadelphia – 2007–11, 2014–15
- Geovanni – San Jose – 2010
- Getterson – Dallas – 2016
- Gilberto – Toronto, Chicago – 2014–16
- Gilberto Flores – MetroStars – 2004–05
- Gilmar – Tampa Bay, MetroStars – 1997–98, 2001
- Gláuber – Columbus – 2013
- Gregore – Inter Miami – 2021–
- Guido – MetroStars – 1997
- Guly do Prado – Chicago – 2015
- Heber – New York City FC – 2019–
- Ibson – Minnesota – 2017–18
- Igor Julião – Kansas City – 2014, 2017
- Ilsinho – Philadelphia – 2016–21
- Jackson – Dallas, Toronto – 2010–15
- Jean Mota – Inter Miami – 2022–
- Jeanderson – Portland – 2015
- Jéferson – Kansas City – 2011
- João Batista – Tampa Bay – 1997
- João Luiz – MetroStars – 1997
- João Paulo – Seattle – 2020–
- Judson – San Jose – 2019–
- Júlio Baptista – Orlando – 2016
- Júlio César – Kansas City – 2011–12
- Júlio César – Toronto – 2014
- Juninho – LA Galaxy, Chicago – 2010–15, 2017, 2019
- Juninho Pernambucano – New York Red Bulls – 2013
- Júnior Carreiro – D.C. United – 2010
- Júnior Urso – Orlando – 2020–
- Kaká— Orlando— 2015–17
- Kléberson – Philadelphia – 2013
- Léo Chú – Seattle – 2021–
- Leo Fernandes – Philadelphia – 2013–14, 2016
- Léo Pereira – Orlando – 2017
- Leonardo – LA Galaxy, Houston – 2010–11, 2013–18
- Lucas Esteves – Colorado – 2021–
- Lucas Venuto – Vancouver – 2019
- Luciano Emílio – D.C. United – 2007–10
- Luiz Araújo – Atlanta – 2021–
- Luiz Camargo – Houston – 2011–13
- Maciel – New England – 2021–
- Maicon Santos – Chivas USA, Toronto, Dallas, D.C. United, Chicago – 2009–13
- Marcelo – Chicago – 2019
- Marcelo Saragosa – LA Galaxy, Dallas, Chivas USA, D.C. United – 2004–10, 2012–13
- Marcelo Sarvas – LA Galaxy, Colorado, D.C. United – 2012–17
- Marquinho – Colorado – 1998
- Marquinhos Pedroso – Dallas, D.C. United – 2018–19
- Matheus Aiás – Orlando – 2020–
- Matheus Davó – Philadelphia – 2021
- Matheus Rossetto – Atlanta – 2020–
- Matheus Silva – San Jose – 2016
- Max – Colorado – 2022–
- Maximiniano – Minnesota – 2018
- Michel – Dallas – 2013–15
- Naldo – LA Galaxy – 2005–06
- Nathan – San Jose – 2021–
- Paulinho McLaren – Miami Fusion – 1998
- Pablo Campos – San Jose, Salt Lake – 2009–10
- Paulo Jr. – Salt Lake – 2010–12
- Paulo Nagamura – LA Galaxy, Toronto, Chivas USA, Kansas City – 2005–16
- PC – Orlando, Vancouver – 2017–19
- Pecka – Salt Lake – 2015
- Pedro Ribeiro – Philadelphia, Orlando – 2014–16
- Phelipe Megiolaro – Dallas – 2020–21
- Rafael – D.C. United – 2013
- Rafael Gomes – Colorado – 2008
- Raphael Augusto – D.C. United – 2013
- Ricardinho – Dallas – 2007–08
- Ricardo Villar – Dallas – 2011–12
- Ricardo Virtuoso – Columbus – 2006–07
- Roberto Gaúcho – Miami Fusion – 1999
- Roberto Linck – New England – 2010
- Robinho – Columbus, Orlando – 2019–20
- Rodrigo Faria – MetroStars, Chicago, San Jose – 2001–03
- Rodrigo Ramos – Chicago – 2016
- Ruan – Orlando – 2019–
- Samuel – LA Galaxy – 2014
- Sergio Santos – Philadelphia – 2019–
- Stefani Miglioranzi – LA Galaxy, Columbus, Philadelphia – 2006–11
- Stefano Pinho – Orlando – 2018
- Talles Magno – New York City FC – 2021–
- Thiago – Chicago – 2005–07
- Thiago – LA Galaxy – 2006
- Thiago Andrade – New York City FC – 2021–
- Thiago Martins – D.C. United, Chivas USA, New York Red Bulls, Colorado – 2003, 2005–06
- Thiago Santos – Dallas – 2020
- Thomás – Seattle – 2015
- Wélton – New England, LA Galaxy, Miami Fusion – 1996–2000
- William Oliveira – Chicago – 2007
- Zico – San Jose – 1997
- Miguel Aceval – Toronto – 2012
- Pablo Aránguiz – Dallas – 2018–19
- José Bizama – Houston – 2019–21
- Carlos Carmona – Atlanta – 2017
- Carlos Farias – San Jose – 1999
- Marcos González – Columbus – 2006–07[b BRA]
- Felipe Gutiérrez – Kansas City – 2018–19
- Kevin Harbottle – Colorado – 2013
- Pablo Hernández – D.C. United – 2010[b ARG]
- Luis Marín – Kansas City – 2015
- Victor Mella – San Jose, New England – 1996, 1998
- Sebastián Miranda – Columbus – 2011–12
- Milovan Mirošević – Columbus – 2012
- Felipe Mora – Portland – 2020–
- Pedro Morales – Vancouver – 2014–16
- Raúl Palacios – Colorado – 2002
- Robbie Robinson – Inter Miami – 2020–[b USA]
- Sebastián Rozental – Columbus – 2006
- Diego Rubio – Kansas City, Colorado – 2016–
- Jeisson Vargas – Montreal – 2018
- Marcelo Vega – MetroStars – 1998
- Abel Aguilar – Dallas – 2018
- Leonel Álvarez – Dallas, New England – 1996, 1998–2001
- Pedro Álvarez – MetroStars – 2001
- Rafael Amaya – San Jose, Colorado – 1996–97
- Juan Pablo Ángel – New York Red Bulls, LA Galaxy, Chivas USA – 2007–12
- Cristian Arango – Los Angeles FC – 2021–
- Victor Arboleda – Portland – 2017–18
- Yair Arboleda – Houston – 2016
- Jhonny Arteaga – New York Red Bulls – 2012
- Dairon Asprilla – Portland – 2015–
- Eduard Atuesta – Los Angeles FC – 2018–21
- Michael Barrios – Dallas, Colorado – 2015–
- Daniel Bedoya – New York City FC – 2019
- Jair Benítez – Dallas – 2009–14
- Michael Bustamante – New York Red Bulls – 2014
- Juan David Cabezas – Houston – 2017–19
- Déiber Caicedo – Vancouver – 2021–
- Juan Caicedo – New England – 2019
- Luis Caicedo – New England – 2018–19, 2021–
- Javier Calle – New York City FC – 2015
- Fernando Cárdenas – New England – 2012
- Juan Castilla – Houston – 2021–
- Fabián Castillo – Dallas – 2011–16
- Jaime Castrillón – Colorado – 2012–13
- Diego Chará – Portland – 2011–
- Yimmi Chará – Portland – 2020–
- Alex Comas – MetroStars – 2000–01
- Wilman Conde – Chicago, New York Red Bulls – 2007–10, 2012
- José Erick Correa – Chivas USA – 2012–13
- Daniel Cruz – Dallas – 2011
- Yamith Cuesta – Chivas USA, Chicago – 2009–11
- Cristian Dájome – Vancouver – 2020–
- Antony de Ávila – MetroStars – 1996–97
- Jhon Durán – Chicago – 2022–
- Oscar Echeverry – New York Red Bulls – 2008
- Andrés Escobar – Dallas – 2014
- Pablo Escobar – Kansas City – 2010
- David Ferreira – Dallas – 2009–13
- Olmes García – Salt Lake – 2013–16
- Yeimar Gómez Andrade – Seattle – 2020–
- Juan Diego González – Philadelphia – 2010
- Yony González – LA Galaxy – 2020
- Hárrison Henao – Colorado – 2012
- Rubén Darío Hernández – MetroStars – 1996
- Sergio Herrera – Columbus – 2010
- Cristian Higuita – Orlando – 2015–19
- Jhon Kennedy Hurtado – Seattle, Chicago, Chivas USA – 2009–14
- Carlos Lizarazo – Dallas – 2016
- John Lozano – New England – 2012
- Christian Mafla – New England – 2021
- Mauro Manotas – Houston – 2015–20
- Gonzalo Martínez – D.C. United – 2008
- Jimmy Medranda – Kansas City, Nashville, Seattle – 2013–
- Jefferson Mena – New York City FC – 2015–16
- Stiven Mendoza – New York City FC – 2016
- Germán Mera – Colorado – 2013
- Faryd Mondragón – Philadelphia – 2011
- Miguel Montaño – Seattle, Montreal – 2010–12
- Fredy Montero – Seattle, Vancouver – 2009–12, 2017, 2019–
- José Moreno – New England – 2012
- Santiago Moreno – Portland – 2021–
- Tressor Moreno – San Jose – 2012
- Hanyer Mosquera – Portland – 2012
- Santiago Mosquera – Dallas – 2018–20
- Jesús Murillo – Los Angeles FC – 2020–
- Cristian Nazarit – Chicago – 2011
- Jáder Obrian – Dallas – 2021–
- Jámison Olave – Salt Lake, New York Red Bulls – 2008–16
- Juan Esteban Ortiz – Dallas – 2016
- Lionard Pajoy – Philadelphia, D.C. United – 2012–13
- Arley Palacios – MetroStars, Miami Fusion – 1998–99
- Óscar Pareja – New England, Dallas – 1998–2005
- Santiago Patiño – Orlando – 2019–20
- Luis Perea – Dallas – 2012
- John Wilmar Pérez – Columbus – 2000–02
- Jorge Perlaza – Portland, Philadelphia – 2011–12
- Hernán Pertúz – Dallas – 2012
- Darwin Quintero – Minnesota, Houston – 2018–
- Wálter Restrepo – Philadelphia – 2016[b USA]
- Andrés Reyes – Inter Miami, New York Red Bulls – 2020–
- Andrés Ricaurte – Dallas – 2020–21
- Carlos Rivas – Orlando, New York Red Bulls – 2015–18
- Nelson Rivas – Montreal – 2012
- Rafael Robayo – Chicago – 2012
- Ángelo Rodríguez – Minnesota – 2018–19
- Milton Rodríguez – Dallas – 2010–11
- Jhohan Romaña – Austin – 2021–
- Eddie Segura – Los Angeles FC – 2019–
- Diego Serna – Miami Fusion, MetroStars, New England, LA Galaxy, Colorado – 1998–2003, 2005
- Carlos Terán – Chicago – 2020–
- Juan Toja – Dallas, New England – 2007–08, 2012–13
- Róger Torres – Philadelphia – 2010–13
- John Jairo Tréllez – Dallas – 1999
- Iván Trujillo – Kansas City – 2008
- Carlos Valderrama – Tampa Bay, Miami Fusion, Colorado – 1996–02
- Carlos Valdés – Philadelphia – 2011–12, 2014
- Adolfo Valencia – MetroStars – 2000–01
- Jhojan Valencia – Austin – 2022–
- John Alexander Valencia – Chivas USA – 2012
- José Adolfo Valencia – Portland – 2013
- Sebastián Velásquez – Salt Lake, New York City FC – 2012–15
- Henry Zambrano – MetroStars, Colorado, D.C. United – 1999–2000, 2002
- Luis Zapata – Colorado – 2012
- Jordy Alcívar – Charlotte – 2022–
- Alexander Alvarado – Orlando – 2020–21
- Juan Luis Anangonó – Chicago – 2013–14
- Xavier Arreaga – Seattle – 2019–
- Luis Bolaños – Chivas USA – 2014
- Miller Bolaños – Chivas USA – 2012–13
- Félix Borja – Chivas USA – 2014
- Diego Calderón – Colorado – 2013
- Leonardo Campana – Inter Miami – 2022–
- José Cifuentes – Los Angeles FC – 2020–
- Jhon Espinoza – Chicago – 2021–
- Víctor Estupiñán – Chivas USA – 2011
- Alan Franco – Charlotte – 2022–
- Ariel Graziani – New England, Dallas, San Jose – 1999–2002[b ARG]
- Carlos Gruezo – Dallas – 2016–19
- Eduardo Hurtado – LA Galaxy, MetroStars, New England – 1996–2000
- Romario Ibarra – Minnesota – 2018–19
- Anderson Julio – Salt Lake – 2021–
- Fausto Klinger – MetroStars – 2001
- Martin Klinger – MetroStars – 2001
- Sebas Méndez – Orlando – 2019–
- Roberto Miña – Dallas – 2006–07
- Oswaldo Minda – Chivas USA – 2012–14
- Diego Palacios – Los Angeles FC – 2019–
- Cristian Penilla – New England – 2018–20
- Joao Plata – Toronto, Salt Lake – 2011–19
- Wellington Sánchez – MetroStars, LA Galaxy – 1998
- Gustavo Vallecilla – Cincinnati – 2021–
- Pedro Vite – Vancouver – 2022–
- Edmundo Zura – San Jose – 2011
- Miguel Almirón – Atlanta – 2017–18
- Luis Amarilla – Minnesota – 2020, 2022–
- Pedro Báez – Salt Lake – 2016
- Cristian Colmán – Dallas – 2017–18
- Josué Colmán – Orlando – 2018–19
- Cecilio Domínguez – Austin – 2021–
- Sebastián Ferreira – Houston – 2022–
- Gastón Giménez – Chicago – 2020–[b ARG][c ARG]
- Jerry Laterza – LA Galaxy – 1997[b USA]
- Erik López – Atlanta – 2021–
- Líder Mármol – Chicago – 2008
- Jesús Medina – New York City FC – 2018–21
- Jorge Moreira – Portland – 2019–20
- Cristhian Paredes – Portland – 2018–
- Rodney Redes – Austin – 2021–
- Alejandro Romero Gamarra – New York Red Bulls – 2018–20[b ARG][c ARG U20]
- Nelson Valdez – Seattle – 2015–16
- Héctor Villalba – Atlanta – 2017–19
- José Alegría – D.C. United – 2001–03
- Carlos Ascues – Orlando – 2018–19[b VEN]
- Alexander Callens – New York City FC – 2017–
- José Carvallo – D.C. United – 2008
- Carlo Chueca – Chivas USA – 2013
- César Díaz Pizarro – San Jose – 2012
- Collin Fernandez – Chicago – 2015–16[b USA][c USA U20][c USA U18]
- Raúl Fernández – Dallas – 2013–14
- Edison Flores – D.C. United – 2020–
- Pedro Gallese – Orlando – 2020–
- Alexi Gómez – Minnesota – 2018
- Marcos López – San Jose – 2019–
- Andrés Mendoza – Columbus – 2010–11
- Percy Olivares – Dallas – 2002
- Andy Polo – Portland – 2018–21
- Yordy Reyna – Vancouver, D.C. United, Charlotte – 2017–
- Raúl Ruidíaz – Seattle – 2018–
- Waldir Sáenz – Colorado – 1998
- Jerry Tamashiro – Miami Fusion – 1998
- Walter Vílchez – Chivas USA – 2013
- Yoshimar Yotún – Orlando – 2017–18
- Nicolás Acevedo – New York City FC – 2020–
- José Aja – Orlando, Vancouver, Minnesota – 2016–18, 2020
- César Araújo – Orlando – 2022–
- Joaquín Ardaiz – Vancouver – 2019
- Egidio Arévalo Ríos – Chicago – 2013
- Jorge Bava – Chicago – 2017
- Rodrigo Brasesco – D.C. United – 2011
- José Cancela – New England, Colorado – 2003–07
- Paolo Cardozo – LA Galaxy, Chivas USA – 2011–12
- Manuel Castro – Atlanta – 2020
- Thomás Chacón – Minnesota – 2019–20
- Diego Cháves – Chicago – 2011[b ARG]
- Guzmán Corujo – Charlotte – 2022–
- Diego Fagúndez – New England, Austin – 2011–
- Álvaro Fernández – Seattle, Chicago – 2010–12, 2016–17
- Sebastián Fernández – Vancouver – 2014
- Francisco Ginella – Los Angeles FC – 2020–
- Santiago González – Montreal – 2014
- Nicolás Lodeiro – Seattle – 2016–
- Alex Martínez – Kansas City – 2014
- Enzo Martínez – Colorado – 2018
- Nicolás Mezquida – Vancouver, Colorado – 2014–
- Lucas Monzón – New York Red Bulls – 2021–[b BRA]
- Martín Morales – Colorado – 2005
- Adrián Paz – Columbus, Colorado – 1996–98
- Mauricio Pereyra – Orlando – 2019–
- Rodrigo Piñeiro – Nashville – 2021
- Pablo Pintos – San Jose – 2014
- Diego Polenta – LA Galaxy – 2019
- Gastón Puerari – Chicago – 2011
- Federico Puppo – Chicago – 2012
- Yeferson Quintana – San Jose – 2018
- Octavio Rivero – Vancouver – 2015–16
- Brian Rodríguez – Los Angeles FC – 2019–
- Diego Rodríguez – Vancouver – 2015
- Santiago Rodríguez – New York City FC – 2021–
- Washington Rodriguez – Dallas – 1996
- Diego Rossi – Los Angeles FC – 2018–21
- Vicente Sánchez – Colorado, Houston – 2013–15, 2017
- Marcelo Silva – Salt Lake – 2017–
- Alejandro Silva González – Montreal – 2018
- Cristian Techera – Vancouver – 2015–18
- David Texeira – Dallas – 2014–15
- Facundo Torres – Orlando – 2022–
- Agustín Viana – Columbus – 2013–14[b USA]
- Diego Viera – Tampa Bay – 1996
- Bernardo Añor – Columbus, Kansas City – 2011–15
- Fernando Aristeguieta – Philadelphia – 2015
- Anthony Blondell – Vancouver – 2018
- Pablo Bonilla – Portland – 2020–
- Jesús Bueno – Philadelphia – 2021–
- Jhonder Cádiz – Nashville – 2020–21
- Wikelman Carmona – New York Red Bulls – 2021–
- Cristian Cásseres Jr. – New York Red Bulls – 2018–
- Carlos Cermeño – Dallas – 2017
- Gabriel Cichero – New York Red Bulls – 2008
- Sergio Córdova – Salt Lake – 2022–
- Rolf Feltscher – LA Galaxy – 2018–20[b SUI][c SUI U21][c SUI U20][c SUI U19][c SUI U17][c SUI U16]
- Alejandro Fuenmayor – Houston – 2018–21
- Erickson Gallardo – Toronto – 2019–20
- Luis González – Dallas – 2017
- José Hernández – Atlanta – 2018
- Ronald Hernández – Atlanta – 2021–
- Yangel Herrera – New York City FC – 2017–18
- Christian Makoun – Inter Miami, Charlotte – 2020–
- Giancarlo Maldonado – Chivas USA – 2010
- José Andrés Martínez – Philadelphia – 2020–
- Josef Martínez – Atlanta – 2017–
- Alejandro Moreno – LA Galaxy, San Jose, Houston, Columbus, Philadelphia, Chivas USA – 2002–12
- Júnior Moreno – D.C. United, Cincinnati – 2018–
- Miguel Navarro – Chicago – 2020–
- Ronaldo Peña – Houston – 2018–20
- Daniel Pereira – Austin – 2021–
- Jeizon Ramírez – Salt Lake – 2020
- Emilio Rentería – Columbus – 2009–12
- Gelmin Rivas – D.C. United – 2020
- Angel Rivillo – Dallas – 2000
- Jorge Rojas – New York Red Bulls – 2008–09
- Giovanni Savarese – MetroStars, New England, San Jose – 1996–99, 2000
- Jefferson Savarino – Salt Lake – 2017–19
- Eduardo Sosa – Columbus – 2018
- Yeferson Soteldo – Toronto – 2021
- Freddy Vargas – Dallas – 2021–
- Renzo Zambrano – Portland – 2019–21
Oceania (OFC)
- Noah Billingsley – Minnesota – 2020
- Michael Boxall – Vancouver, Minnesota – 2011, 2017–
- Andrew Boyens – Toronto, New York Red Bulls, Chivas USA, LA Galaxy – 2007–09, 2011–12
- Jeremy Brockie – Toronto – 2013
- Elliot Collier – Chicago – 2018, 2020–21
- Kip Colvey – San Jose, Colorado – 2016, 2018[b USA]
- Simon Elliott – LA Galaxy, Columbus, San Jose, Chivas USA – 1999–2005, 2009, 2011
- Jake Gleeson – Portland – 2011, 2016–18
- Dan Keat – LA Galaxy – 2011–12[b ENG]
- Cameron Knowles – Salt Lake – 2005
- Tony Lochhead – New England, Chivas USA – 2006, 2014
- Stefan Marinovic – Vancouver – 2017–18
- James Musa – Kansas City, Minnesota – 2017, 2020[b ENG]
- Ryan Nelsen – D.C. United – 2001–04
- Duncan Oughton – Columbus – 2001–04, 2006–10
- Winston Reid – Kansas City – 2020[c DEN U21][c DEN U20][c DEN U19]
- Jarrod Smith – Toronto – 2008
- Tommy Smith – Colorado – 2018–19[b ENG][c ENG U18][c ENG U17]
- Bill Tuiloma – Portland – 2018–
- Deklan Wynne – Colorado – 2018–19[b RSA]
Notes
- ^ Born in Algeria
- ^ Born in Argentina
- ^ Born in Australia
- ^ Born in Austria
- ^ Born in Azerbaijan (then part of the Soviet Union)
- ^ Born in Bosnia and Herzegovina
- ^ Born in Bosnia and Herzegovina (then part of Yugoslavia)
- ^ Born in Brazil
- ^ Born in Canada
- ^ Born in Colombia
- ^ Born in the Czech Republic
- ^ Born in the Democratic Republic of the Congo (then Zaire)
- ^ Born in Ecuador
- ^ Born in England
- ^ Born in Ethiopia
- ^ Born in France
- ^ Born in Germany
- ^ Born in Guinea-Bissau
- ^ Born in Guyana
- ^ Born in the Ivory Coast
- ^ Born in Japan
- ^ Born in Latvia (then part of the Soviet Union)
- ^ Born in Liberia
- ^ Born in Malaysia
- ^ Born in Mali
- ^ Born in Mexico
- ^ Born in Montenegro (then part of SFR Yugoslavia)
- ^ Born in Mozambique
- ^ Born in the Netherlands
- ^
- ^ Born in Nigeria
- ^ Born in Norway
- ^ Born in Portugal
- ^ Born in the Republic of Macedonia (then part of Yugoslavia)
- ^
- ^ Born in Russia
- ^ Born in Serbia (then part of SFR Yugoslavia)
- ^ Born in Sierra Leone
- ^ Born in South Africa
- ^ Born in Suriname
- ^ Born in Sweden
- ^ Born in Switzerland
- ^ Born in The Gambia
- ^ Born in the United States
- ^ Born in Venezuela
- ^ Born in West Germany (now part of Germany)
- ^ Born in Zambia
- ^
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- ^ Capped for the France national football team
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- ^ Capped for the Galicia national football team
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- ^ Capped for the Guyana national football team
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