GJC3

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GJC3
Identifiers
Aliases GJC3, CX29, CX30.2, CX31.3, GJE1, gap junction protein gamma 3
External IDs MGI: 2153041 HomoloGene: 15399 GeneCards: 349149
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_181538

NM_080450

RefSeq (protein)

NP_853516.1

NP_536698.2

Location (UCSC) Chr 7: 99.92 – 99.93 Mb Chr 5: 137.95 – 137.96 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Gap junction gamma-3, also known as connexin-29 (Cx29) or gap junction epsilon-1 (GJE1), is a protein that in humans is encoded by the GJC3 gene.[1]

GJC3 is a conexin.

Function[edit]

This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells.[1]

Clinical significance[edit]

Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[1]

References[edit]

Further reading[edit]