KCNK10

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KCNK10
Available structures
PDB Human UniProt search: PDBe RCSB
Identifiers
Aliases KCNK10, K2p10.1, PPP1R97, TREK-2, TREK2, potassium two pore domain channel subfamily K member 10
External IDs MGI: 1919508 HomoloGene: 11321 GeneCards: KCNK10
Targeted by Drug
arachidonic acid, halothane[1]
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_021161
NM_138317
NM_138318

NM_029911
NM_001316664
NM_001316665
NM_001316666

RefSeq (protein)

NP_066984
NP_612190
NP_612191

n/a

Location (UCSC) Chr 14: 88.18 – 88.33 Mb Chr 12: 98.43 – 98.58 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Potassium channel, subfamily K, member 10, also known as KCNK10 is a human gene. The protein encoded by this gene, K2P10.1, is a potassium channel containing two pore-forming P domains.[4][5][6]

See also[edit]

References[edit]

  1. ^ "Drugs that physically interact with Potassium two pore domain channel subfamily K member 10 view/edit references on wikidata". 
  2. ^ "Human PubMed Reference:". 
  3. ^ "Mouse PubMed Reference:". 
  4. ^ Lesage F, Terrenoire C, Romey G, Lazdunski M (September 2000). "Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors". The Journal of Biological Chemistry. 275 (37): 28398–405. doi:10.1074/jbc.M002822200. PMID 10880510. 
  5. ^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (December 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacological Reviews. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106. 
  6. ^ Dong YY, Pike AC, Mackenzie A, McClenaghan C, Aryal P, Dong L, Quigley A, Grieben M, Goubin S, Mukhopadhyay S, Ruda GF, Clausen MV, Cao L, Brennan PE, Burgess-Brown NA, Sansom MS, Tucker SJ, Carpenter EP (March 2015). "K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac". Science. 347 (6227): 1256–9. doi:10.1126/science.1261512. PMID 25766236. 

Further reading[edit]

External links[edit]