GJD4

From Wikipedia, the free encyclopedia
Jump to: navigation, search
GJD4
Identifiers
Aliases GJD4, CX40.1, gap junction protein delta 4
External IDs MGI: 2444990 HomoloGene: 17692 GeneCards: 219770
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_153368

NM_153086

RefSeq (protein)

NP_699199.2

NP_694726.2

Location (UCSC) Chr 10: 35.61 – 35.61 Mb Chr 18: 9.28 – 9.28 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Gap junction delta-4 protein (GJD4), also known as connexin-40.1 (Cx40.1), is a protein that in humans is encoded by the GJD4 gene.[1]

Function[edit]

Connexins, such as GJD4, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[1][2]

References[edit]

  1. ^ a b "Entrez Gene: gap junction protein". 
  2. ^ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.