GJD4

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GJD4
Identifiers
AliasesGJD4, CX40.1, gap junction protein delta 4
External IDsMGI: 2444990 HomoloGene: 17692 GeneCards: GJD4
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for GJD4
Genomic location for GJD4
Band10p11.21Start35,605,410 bp[1]
End35,608,935 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_153368

NM_153086

RefSeq (protein)

NP_699199

NP_694726

Location (UCSC)Chr 10: 35.61 – 35.61 MbChr 18: 9.28 – 9.28 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Gap junction delta-4 protein (GJD4), also known as connexin-40.1 (Cx40.1), is a protein that in humans is encoded by the GJD4 gene.[5]

Function[edit]

Connexins, such as GJD4, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits.[5][6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000177291 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000036855 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ a b "Entrez Gene: gap junction protein". 
  6. ^ Söhl G, Nielsen PA, Eiberger J, Willecke K (2003). "Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues". Cell Commun. Adhes. 10 (1): 27–36. doi:10.1080/15419060302063. PMID 12881038. 

This article incorporates text from the United States National Library of Medicine, which is in the public domain.