KCNK1

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KCNK1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases KCNK1, DPK, HOHO, K2P1, K2p1.1, KCNO1, TWIK-1, TWIK1, potassium two pore domain channel subfamily K member 1
External IDs MGI: 109322 HomoloGene: 1691 GeneCards: KCNK1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002245

NM_008430

RefSeq (protein)

NP_002236

NP_032456.2
NP_032456

Location (UCSC) Chr 1: 233.61 – 233.67 Mb Chr 8: 126 – 126.03 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Potassium channel subfamily K member 1 is a protein that in humans is encoded by the KCNK1 gene.[3][4][5]

This gene encodes K2P1.1, a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, and it may require other non-pore-forming proteins for activity.[5]

See also[edit]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Lesage F, Mattei M, Fink M, Barhanin J, Lazdunski M (Dec 1996). "Assignment of the human weak inward rectifier K+ channel TWIK-1 gene to chromosome 1q42-q43". Genomics. 34 (1): 153–5. doi:10.1006/geno.1996.0259. PMID 8661042. 
  4. ^ Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev. 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106. 
  5. ^ a b "Entrez Gene: KCNK1 potassium channel, subfamily K, member 1". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.