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Potassium channel, voltage gated Shaw related subfamily C, member 4
Protein KCNC4 PDB 1b4g.png
PDB rendering based on 1b4g.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols KCNC4 ; C1orf30; HKSHIIIC; KSHIIIC; KV3.4
External IDs OMIM176265 MGI96670 HomoloGene68427 IUPHAR: 551 GeneCards: KCNC4 Gene
RNA expression pattern
PBB GE KCNC4 208251 at tn.png
More reference expression data
Species Human Mouse
Entrez 3749 99738
Ensembl ENSG00000116396 ENSMUSG00000027895
UniProt Q03721 Q8R1C0
RefSeq (mRNA) NM_001039574 NM_145922
RefSeq (protein) NP_001034663 NP_666034
Location (UCSC) Chr 1:
110.21 – 110.28 Mb
Chr 3:
107.44 – 107.46 Mb
PubMed search [1] [2]

Potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), also known as Kv3.4, is a human gene.[1]

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.