KCNC4

From Wikipedia, the free encyclopedia
Jump to: navigation, search
KCNC4
Protein KCNC4 PDB 1b4g.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases KCNC4, C1orf30, HKSHIIIC, KSHIIIC, KV3.4, potassium voltage-gated channel subfamily C member 4
External IDs MGI: 96670 HomoloGene: 68427 GeneCards: 3749
RNA expression pattern
PBB GE KCNC4 208251 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001039574
NM_004978
NM_153763

NM_145922

RefSeq (protein)

NP_001034663.1
NP_004969.2

NP_666034.1

Location (UCSC) Chr 1: 110.21 – 110.28 Mb Chr 3: 107.44 – 107.46 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Potassium voltage-gated channel, Shaw-related subfamily, member 4 (KCNC4), also known as Kv3.4, is a human gene.[1]

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Several transcript variants encoding different isoforms have been found for this gene.[1]

See also[edit]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.