CatSper4: Difference between revisions
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{{GNF_Protein_box |
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0 |
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| Name = CatSper4 |
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| image = |
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| image_source = |
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| PDB = |
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| HGNCid = 23220 |
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| MGIid = 3043288 |
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| Symbol = CATSPER4 |
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| AltSymbols = |
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| OMIM = 609121 |
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| ECnumber = |
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| Homologene = 18638 |
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| GeneAtlas_image = |
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| Function = Cation channel of sperm |
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| NotAProtein = |
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| Orthologs = {{GNF_Ortholog_box |
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| Hs_EntrezGene = 378807 |
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| Hs_Ensembl = ENSG00000188782 |
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| Hs_RefseqProtein = NP_937770 |
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| Hs_RefseqmRNA = NM_198137 |
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| Hs_GenLoc_db = |
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| Hs_GenLoc_chr = 1 |
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| Hs_GenLoc_start = 134331495 |
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| Hs_GenLoc_end = 134375291 |
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| Hs_Uniprot = Q7RTX7 |
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| Mm_EntrezGene = 329954 |
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| Mm_Ensembl = ENSMUSG00000048003 |
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| Mm_RefseqmRNA = NM_177866 |
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| Mm_RefseqProtein = NP_808534 |
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| Mm_GenLoc_db = |
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| Mm_GenLoc_chr = 4 |
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| Mm_GenLoc_start = 133767885 |
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| Mm_GenLoc_end = 133783283 |
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| Mm_Uniprot = Q8BVN3 |
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}} |
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}} |
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'''CatSper4''', is a [[protein]] which in humans is encoded by the ''CATSPER4'' [[gene]].<ref name="pmid12932298">{{cite journal | author = Lobley A, Pierron V, Reynolds L, Allen L, Michalovich D | title = Identification of human and mouse CatSper3 and CatSper4 genes: characterisation of a common interaction domain and evidence for expression in testis | journal = Reprod. Biol. Endocrinol. | volume = 1 | issue = | pages = 53 | year = 2003 | month = August | pmid = 12932298 | pmc = 184451 | doi = 10.1186/1477-7827-1-53 | url = | issn = }}</ref><ref name="pmid17227845">{{cite journal | author = Qi H, Moran MM, Navarro B, Chong JA, Krapivinsky G, Krapivinsky L, Kirichok Y, Ramsey IS, Quill TA, Clapham DE | title = All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 104 | issue = 4 | pages = 1219–23 | year = 2007 | month = January | pmid = 17227845 | pmc = 1770895 | doi = 10.1073/pnas.0610286104 | url = | issn = }}</ref><ref name="pmid16382101">{{cite journal | author = Clapham DE, Garbers DL | title = International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels | journal = Pharmacol. Rev. | volume = 57 | issue = 4 | pages = 451–4 | year = 2005 | month = December | pmid = 16382101 | doi = 10.1124/pr.57.4.7 | url = | issn = }}</ref> CatSper1 is a member of the [[cation channels of sperm]] family of protein. The four proteins in this family together form a [[calcium (biology)|Ca<sup>2+</sub>]]-permeant [[ion channel]] specific essential for the correct function of sperm cells. <ref name="IUPHAR-DB">*{{cite web | url = http://www.iuphar-db.org/IC/FamilyIntroductionForward?familyId=13| title = CatSper and Two-Pore Channels: Introduction | accessdate = | author = | authorlink = | coauthors = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | language = | archiveurl = | archivedate = | quote = }}</ref> |
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==External links== |
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*{{cite web | url = http://www.iuphar-db.org/IC/ObjectDisplayForward?objectId=54&familyId=13 | title = CatSper and Two-Pore Channels: CatSper4 | accessdate = | author = | authorlink = | coauthors = | date = | format = | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | pages = | language = | archiveurl = | archivedate = | quote = }} |
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==References== |
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{{reflist}} |
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{{membrane-protein-stub}} |
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{{Ion channels}} |
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[[Category:Ion channels]] |
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Revision as of 00:33, 28 July 2009
CatSper4, is a protein which in humans is encoded by the CATSPER4 gene.[5][6][7] CatSper1 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells. [8]
External links
- "CatSper and Two-Pore Channels: CatSper4". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
{{cite web}}: Cite has empty unknown parameter:|coauthors=(help)
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000188782 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000048003 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Lobley A, Pierron V, Reynolds L, Allen L, Michalovich D (2003). "Identification of human and mouse CatSper3 and CatSper4 genes: characterisation of a common interaction domain and evidence for expression in testis". Reprod. Biol. Endocrinol. 1: 53. doi:10.1186/1477-7827-1-53. PMC 184451. PMID 12932298.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link) - ^ Qi H, Moran MM, Navarro B, Chong JA, Krapivinsky G, Krapivinsky L, Kirichok Y, Ramsey IS, Quill TA, Clapham DE (2007). "All four CatSper ion channel proteins are required for male fertility and sperm cell hyperactivated motility". Proc. Natl. Acad. Sci. U.S.A. 104 (4): 1219–23. doi:10.1073/pnas.0610286104. PMC 1770895. PMID 17227845.
{{cite journal}}: Unknown parameter|month=ignored (help)CS1 maint: multiple names: authors list (link) - ^ Clapham DE, Garbers DL (2005). "International Union of Pharmacology. L. Nomenclature and structure-function relationships of CatSper and two-pore channels". Pharmacol. Rev. 57 (4): 451–4. doi:10.1124/pr.57.4.7. PMID 16382101.
{{cite journal}}: Unknown parameter|month=ignored (help) - ^ *"CatSper and Two-Pore Channels: Introduction". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.
{{cite web}}: Cite has empty unknown parameter:|coauthors=(help)
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