Aquaporin-5 is a protein that in humans is encoded by the AQP5gene.[5][6]
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions [6]. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.[6]
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Chen Z, Wang X, Gao L, et al. (2006). "Regulation of MUC5AC mucin secretion by depletion of AQP5 in SPC-A1 cells". Biochem. Biophys. Res. Commun. 342 (3): 775–81. doi:10.1016/j.bbrc.2006.01.103. PMID16500622.
Pedersen PS, Braunstein TH, Jørgensen A, et al. (2007). "Stimulation of aquaporin-5 and transepithelial water permeability in human airway epithelium by hyperosmotic stress". Pflügers Arch. 453 (6): 777–85. doi:10.1007/s00424-006-0157-3. PMID17043812.
Skowron-zwarg M, Boland S, Caruso N, et al. (2007). "Interleukin-13 interferes with CFTR and AQP5 expression and localization during human airway epithelial cell differentiation". Exp. Cell Res. 313 (12): 2695–702. doi:10.1016/j.yexcr.2007.02.035. PMID17553491.