Cyclic nucleotide gated channel beta 3

CNGB3
Identifiers
Aliases	CNGB3, ACHM1, Cyclic nucleotide gated channel beta 3, cyclic nucleotide gated channel subunit beta 3
External IDs	OMIM: 605080; MGI: 1353562; HomoloGene: 40908; GeneCards: CNGB3; OMA:CNGB3 - orthologs
Gene location (Human) Chr. Chromosome 8 (human) Band 8q21.3 Start 86,553,977 bp End 86,743,675 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 A3 Start 19,280,850 bp End 19,510,623 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle retinal pigment epithelium gonad Achilles tendon male germ cell sperm corpus callosum Epithelium of choroid plexus apex of heart bone marrow Top expressed in pineal gland neural layer of retina spermatid lumbar subsegment of spinal cord myocardium of ventricle epithelium of lens lumbar spinal ganglion trachea right ventricle tibiofemoral joint More reference expression data BioGPS More reference expression data
Gene ontology Molecular function intracellular cGMP-activated cation channel activity voltage-gated potassium channel activity nucleotide binding cGMP binding intracellular cyclic nucleotide activated cation channel activity intracellular cAMP-activated cation channel activity Cellular component integral component of membrane photoreceptor outer segment membrane transmembrane transporter complex integral component of plasma membrane Biological process regulation of membrane potential cation transport ion transport cation transmembrane transport signal transduction visual perception response to stimulus potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54714 30952 Ensembl ENSG00000170289 ENSMUSG00000056494 UniProt Q9NQW8 Q9JJZ9 RefSeq (mRNA) NM_019098 NM_013927 RefSeq (protein) NP_061971 NP_038955 Location (UCSC) Chr 8: 86.55 – 86.74 Mb Chr 4: 19.28 – 19.51 Mb PubMed search
Wikidata
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Cyclic nucleotide gated channel beta 3, also known as CNGB3, is a human gene encoding an ion channel protein.

See also

• Cyclic nucleotide-gated ion channel
• Stargardt disease

External links

• GeneReviews/NIH/NCBI/UW entry on Achromatopsia
• OMIM entries on Achromatopsia
• CNGB3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.