KCNH5

KCNH5
Identifiers
Aliases	KCNH5, EAG2, H-EAG2, Kv10.2, hEAG2, potassium voltage-gated channel subfamily H member 5
External IDs	OMIM: 605716; MGI: 3584508; HomoloGene: 15858; GeneCards: KCNH5; OMA:KCNH5 - orthologs
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	75,224,106 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; retinal pigment epithelium; ; prefrontal cortex; ; Brodmann area 9; ; superior frontal gyrus; ; Brodmann area 46; ; Brodmann area 23; ; postcentral gyrus; ; hypothalamus; ; corpus callosum;
	Top expressed in
	superior frontal gyrus; ; visual cortex; ; primary visual cortex; ; neural layer of retina; ; zygote; ; dentate gyrus of hippocampal formation granule cell; ; inferior colliculi; ; piriform cortex; ; lumbar subsegment of spinal cord; ; embryo;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	potassium channel activity; voltage-gated ion channel activity; calmodulin binding; ion channel activity; voltage-gated potassium channel activity; phosphorelay sensor kinase activity; transmembrane transporter binding; protein heterodimerization activity;
Cellular component	integral component of membrane; membrane; plasma membrane; intracellular anatomical structure; cell surface; integral component of plasma membrane;
Biological process	regulation of G2/M transition of mitotic cell cycle; signal transduction; regulation of membrane potential; regulation of ion transmembrane transport; ion transport; potassium ion transport; transmembrane transport; potassium ion transmembrane transport; phosphorelay signal transduction system;
	Sources:Amigo / QuickGO
Orthologs
	27133
	238271
	n/a
	ENSMUSG00000034402
	Q8NCM2
	Q920E3
	NM_139318; NM_172375; NM_172376
	NM_172805
	NP_647479; NP_758963
	NP_766393
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel, subfamily H (eag-related), member 5, also known as KCNH5, is a human gene encoding the K_v10.2 protein.^[4]

Template:PBB Summary

Mutations in this gene have been linked to cases of early onset Epilepsy.(10.1111/epi.12201)

References

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034402 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: KCNH5 potassium voltage-gated channel, subfamily H (eag-related), member 5".

References

Further reading