KvLQT3

KCNQ3
Identifiers
Aliases	KCNQ3, BFNC2, EBN2, KV7.3, potassium voltage-gated channel subfamily Q member 3
External IDs	OMIM: 602232; MGI: 1336181; HomoloGene: 20949; GeneCards: KCNQ3; OMA:KCNQ3 - orthologs
Gene location (Human)
Chr.	Chromosome 8 (human)
End	132,481,095 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	66,158,491 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; lateral nuclear group of thalamus; ; Brodmann area 23; ; pars compacta; ; endothelial cell; ; pons; ; middle temporal gyrus; ; postcentral gyrus; ; pars reticulata; ; entorhinal cortex;
	Top expressed in
	medial geniculate nucleus; ; lateral geniculate nucleus; ; medial dorsal nucleus; ; piriform cortex; ; olfactory tubercle; ; primary motor cortex; ; globus pallidus; ; cingulate gyrus; ; ventromedial nucleus; ; temporal lobe;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	voltage-gated ion channel activity; ion channel activity; voltage-gated potassium channel activity; potassium channel activity; calmodulin binding; protein binding; delayed rectifier potassium channel activity;
Cellular component	membrane; plasma membrane; node of Ranvier; cell surface; axon initial segment; integral component of membrane; integral component of plasma membrane; voltage-gated potassium channel complex;
Biological process	membrane hyperpolarization; regulation of ion transmembrane transport; ion transport; transmembrane transport; chemical synaptic transmission; potassium ion transport; potassium ion transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	3786
	110862
	ENSG00000184156
	ENSMUSG00000056258
	O43525
	Q8K3F6
	NM_001204824; NM_004519
	NM_152923
	NP_001191753; NP_004510
	NP_690887
	Wikidata
View/Edit Human	View/Edit Mouse

K_v7.3 (KvLQT3) is a potassium channel protein coded for by the gene KCNQ3.^[5]

It is associated with benign familial neonatal epilepsy.

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Interactions

KvLQT3 has been shown to interact with KCNQ5.^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000184156 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056258 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: KCNQ3 potassium voltage-gated channel, KQT-like subfamily, member 3".
^ Yus-Nájera, E; Muñoz A; Salvador N; Jensen B S; Rasmussen H B; Defelipe J; Villarroel A (2003). "Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation". Neuroscience. 120 (2). United States: 353–64. doi:10.1016/S0306-4522(03)00321-X. ISSN 0306-4522. PMID 12890507. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

External links

KCNQ3+Potassium+Channel at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000184156 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000056258 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: KCNQ3 potassium voltage-gated channel, KQT-like subfamily, member 3".

[pmid12890507-6] Yus-Nájera, E; Muñoz A; Salvador N; Jensen B S; Rasmussen H B; Defelipe J; Villarroel A (2003). "Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation". Neuroscience. 120 (2). United States: 353–64. doi:10.1016/S0306-4522(03)00321-X. ISSN 0306-4522. PMID 12890507. {{cite journal}}: Cite has empty unknown parameters: |laydate=, |laysource=, and |laysummary= (help)

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Interactions

References

Further reading

External links