SCN3A

SCN3A
Identifiers
Aliases	SCN3A, NAC3, Nav1.3, sodium voltage-gated channel alpha subunit 3, FFEVF4, EIEE62, DEE62
External IDs	OMIM: 182391; MGI: 98249; HomoloGene: 56005; GeneCards: SCN3A; OMA:SCN3A - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2q24.3 Start 165,087,526 bp End 165,204,050 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2 C1.3|2 38.55 cM Start 65,287,462 bp End 65,397,971 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endothelial cell middle temporal gyrus entorhinal cortex Brodmann area 23 orbitofrontal cortex Region I of hippocampus proper postcentral gyrus Brodmann area 46 cerebellar vermis superior frontal gyrus Top expressed in superior cervical ganglion habenula dorsal striatum endothelial cell of lymphatic vessel dorsomedial hypothalamic nucleus ventromedial nucleus piriform cortex paraventricular nucleus of hypothalamus trigeminal ganglion ventral tegmental area More reference expression data BioGPS More reference expression data
Gene ontology Molecular function sodium channel activity voltage-gated ion channel activity ion channel activity voltage-gated sodium channel activity Cellular component voltage-gated sodium channel complex cytoplasm integral component of membrane membrane plasma membrane axon Biological process membrane depolarization during action potential sodium ion transmembrane transport sodium ion transport regulation of ion transmembrane transport ion transport transmembrane transport ion transmembrane transport neuronal action potential Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6328 20269 Ensembl ENSG00000153253 ENSMUSG00000057182 UniProt Q9NY46 A2ASI5 RefSeq (mRNA) NM_001081676 NM_001081677 NM_006922 NM_018732 NM_001355166 NM_001355167 NM_001355168 NM_001355169 NM_001355170 NM_001355171 RefSeq (protein) NP_001075145 NP_001075146 NP_008853 NP_001342095 NP_001342096 NP_001342097 NP_001342098 NP_001342099 NP_001342100 NP_061202 Location (UCSC) Chr 2: 165.09 – 165.2 Mb Chr 2: 65.29 – 65.4 Mb PubMed search
Wikidata
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Sodium channel, voltage-gated, type III, alpha subunit (SCN3A) is a protein that in humans is encoded by the Nav1.3 gene.

See also

• Sodium channel

External links

• SCN3A+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.