SGK2

SGK2
Identifiers
Aliases	SGK2, H-dJ138B7.2, serine/threonine kinase 2, serum/glucocorticoid regulated kinase 2
External IDs	OMIM: 607589 MGI: 1351318 HomoloGene: 8446 GeneCards: SGK2
Gene location (Human)
Chr.	Chromosome 20 (human)
End	43,588,237 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	162,856,047 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; rectum; ; kidney; ; renal medulla; ; duodenum; ; body of pancreas; ; kidney tubule; ; corpus callosum; ; jejunal mucosa; ; body of stomach;
	Top expressed in
	kidney; ; left lobe of liver; ; proximal tubule; ; pyloric antrum; ; mucous cell of stomach; ; epithelium of stomach; ; large intestine; ; ileum; ; intestinal villus; ; left colon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ATP binding; calcium channel regulator activity; sodium channel regulator activity; protein kinase activity; potassium channel regulator activity; kinase activity; chloride channel regulator activity; nucleotide binding; transferase activity; protein serine/threonine kinase activity;
Cellular component	nucleus; intracellular anatomical structure; cytosol; cytoplasm; nucleoplasm; cellular component;
Biological process	response to oxidative stress; positive regulation of transporter activity; regulation of cell population proliferation; ion transmembrane transport; protein phosphorylation; intracellular signal transduction; peptidyl-serine phosphorylation; regulation of apoptotic process; phosphorylation; regulation of cell growth;
	Sources:Amigo / QuickGO
Orthologs
	10110
	27219
	ENSG00000101049
	ENSMUSG00000017868
	Q9HBY8; Q5H8Y5
	Q9QZS5
	NM_170693; NM_001199264; NM_016276
	NM_001291152; NM_001291154; NM_013731
	NP_001186193; NP_057360; NP_733794
	NP_001278081; NP_001278083; NP_038759
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase Sgk2 is an enzyme that in humans is encoded by the SGK2 gene.^[5]^[6]

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References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000101049 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000017868 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kobayashi T, Deak M, Morrice N, Cohen P (Jan 2000). "Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase". Biochem J. 344 Pt 1: 189–97. doi:10.1042/0264-6021:3440189. PMC 1220630. PMID 10548550.
^ "Entrez Gene: SGK2 serum/glucocorticoid regulated kinase 2".

External links

SGK2 human gene location in the UCSC Genome Browser.
SGK2 human gene details in the UCSC Genome Browser.

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This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000101049 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000017868 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10548550-5] Kobayashi T, Deak M, Morrice N, Cohen P (Jan 2000). "Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase". Biochem J. 344 Pt 1: 189–97. doi:10.1042/0264-6021:3440189. PMC 1220630. PMID 10548550.

[entrez-6] "Entrez Gene: SGK2 serum/glucocorticoid regulated kinase 2".

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v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

References

Further reading

External links