Jump to content

7-Hydroxyamoxapine

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Edgar181 (talk | contribs) at 16:38, 1 February 2018 (added Category:Human drug metabolites using HotCat). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

7-Hydroxyamoxapine
Names
IUPAC name
2-chloro-11-(piperazin-1-yl)dibenzo [b,f][1,4]oxazepin-7-ol
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C17H16ClN3O2/c18-11-1-4-15-13(9-11)17(21-7-5-19-6-8-21)20-14-3-2-12(22)10-16(14)23-15/h1-4,9-10,19,22H,5-8H2 checkY
    Key: MEUGUMOVYNSGEW-UHFFFAOYSA-N checkY
  • InChI=1/C17H16ClN3O2/c18-11-1-4-15-13(9-11)17(21-7-5-19-6-8-21)20-14-3-2-12(22)10-16(14)23-15/h1-4,9-10,19,22H,5-8H2
    Key: MEUGUMOVYNSGEW-UHFFFAOYAF
  • Clc2ccc1Oc4c(/N=C(\c1c2)N3CCNCC3)ccc(O)c4
Properties
C17H16ClN3O2
Molar mass 329.78 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

7-Hydroxyamoxapine is an active metabolite of amoxapine (Asendin). It contributes to amoxapine's pharmacology.[1][2]

See also

References

  1. ^ Jue, SG; Dawson, GW; Brogden, RN (July 1982). "Amoxapine: A Review of its Pharmacology and Efficacy in Depressed States". Drugs. 24 (1): 1–23. doi:10.2165/00003495-198224010-00001. PMID 7049659.
  2. ^ Calvo, B; García, MJ; Pedraz, JL; Mariño, EL; Domínguez-Gil, A (April 1985). "Pharmacokinetics of amoxapine and its active metabolites". International journal of clinical pharmacology, therapy, and toxicology. 23 (4): 180–185. PMID 3997304.


Stub icon

This biochemistry article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=7-Hydroxyamoxapine&oldid=823494968"