FZD5

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Frizzled class receptor 5
Identifiers
Symbols FZD5 ; C2orf31; HFZ5
External IDs OMIM601723 MGI108571 HomoloGene2590 IUPHAR: FZD5 GeneCards: FZD5 Gene
RNA expression pattern
PBB GE FZD5 206136 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 7855 14367
Ensembl ENSG00000163251 ENSMUSG00000045005
UniProt Q13467 Q9EQD0
RefSeq (mRNA) NM_003468 NM_001033193
RefSeq (protein) NP_003459 NP_001036124
Location (UCSC) Chr 2:
208.63 – 208.63 Mb
Chr 1:
64.73 – 64.74 Mb
PubMed search [1] [2]

Frizzled-5 is a protein that in humans is encoded by the FZD5 gene.[1][2][3]

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.[3]

See also[edit]

References[edit]

  1. ^ Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (Jun 1996). "A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled". J Biol Chem 271 (8): 4468–76. doi:10.1074/jbc.271.8.4468. PMID 8626800. 
  2. ^ Saitoh T, Hirai M, Katoh M (Jun 2001). "Molecular cloning and characterization of human Frizzled-5 gene on chromosome 2q33.3-q34 region". Int J Oncol 19 (1): 105–10. doi:10.3892/ijo.19.1.105. PMID 11408929. 
  3. ^ a b "Entrez Gene: FZD5 frizzled homolog 5 (Drosophila)". 

External links[edit]

  • "Frizzled Receptors: FZD5". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.