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Pyrimidinergic receptor P2Y, G-protein coupled, 4
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols P2RY4 ; NRU; P2P; P2Y4; UNR
External IDs OMIM300038 MGI1926594 HomoloGene20568 IUPHAR: 325 ChEMBL: 2123 GeneCards: P2RY4 Gene
RNA expression pattern
PBB GE P2RY4 221466 at tn.png
More reference expression data
Species Human Mouse
Entrez 5030 57385
Ensembl ENSG00000186912 ENSMUSG00000044359
UniProt P51582 Q9JJS7
RefSeq (mRNA) NM_002565 NM_020621
RefSeq (protein) NP_002556 NP_065646
Location (UCSC) Chr X:
69.48 – 69.48 Mb
Chr X:
100.59 – 100.59 Mb
PubMed search [1] [2]

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.[1][2]

The product of this gene, P2Y4, belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP.[2]

See also[edit]


  1. ^ Communi D, Pirotton S, Parmentier M, Boeynaems JM (Feb 1996). "Cloning and functional expression of a human uridine nucleotide receptor". J Biol Chem 270 (52): 30849–52. doi:10.1074/jbc.270.52.30849. PMID 8537336. 
  2. ^ a b "Entrez Gene: P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4". 

External links[edit]

  • "P2Y Receptors: P2Y4". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.