TAS2R1

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Taste receptor, type 2, member 1
Identifiers
Symbols TAS2R1 ; T2R1; TRB7
External IDs OMIM604796 MGI2681253 HomoloGene10480 IUPHAR: TAS2R1 GeneCards: TAS2R1 Gene
RNA expression pattern
PBB GE TAS2R1 221324 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 50834 57254
Ensembl ENSG00000169777 ENSMUSG00000045267
UniProt Q9NYW7 Q9JKT2
RefSeq (mRNA) NM_019599 NM_020503
RefSeq (protein) NP_062545 NP_065249
Location (UCSC) Chr 5:
9.63 – 9.71 Mb
Chr 15:
32.18 – 32.18 Mb
PubMed search [1] [2]

Taste receptor type 2 member 1 is a protein that in humans is encoded by the TAS2R1 gene.[1][2][3]

Function[edit]

This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil.[3]

See also[edit]

References[edit]

  1. ^ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (Apr 2000). "A novel family of mammalian taste receptors". Cell 100 (6): 693–702. doi:10.1016/S0092-8674(00)80705-9. PMID 10761934. 
  2. ^ Matsunami H, Montmayeur JP, Buck LB (Apr 2000). "A family of candidate taste receptors in human and mouse". Nature 404 (6778): 601–4. doi:10.1038/35007072. PMID 10766242. 
  3. ^ a b "Entrez Gene: TAS2R1 taste receptor, type 2, member 1". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.