TAS2R50

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Taste receptor, type 2, member 50
Identifiers
Symbols TAS2R50 ; T2R50; T2R51; TAS2R51
External IDs OMIM609627 HomoloGene88474 IUPHAR: 677 GeneCards: TAS2R50 Gene
Orthologs
Species Human Mouse
Entrez 259296 n/a
Ensembl ENSG00000212126 n/a
UniProt P59544 n/a
RefSeq (mRNA) NM_176890 n/a
RefSeq (protein) NP_795371 n/a
Location (UCSC) Chr 12:
11.14 – 11.14 Mb
n/a
PubMed search [1] n/a

Taste receptor type 2 member 50 is a protein that in humans is encoded by the TAS2R50 gene.[1][2][3][4]

Function[edit]

TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway.[2] See also TAS2R10.[4]

See also[edit]

References[edit]

  1. ^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. 
  2. ^ a b Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (Feb 2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet Genome Res 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440. 
  3. ^ Shiffman D, Ellis SG, Rowland CM, Malloy MJ, Luke MM, Iakoubova OA, Pullinger CR, Cassano J, Aouizerat BE, Fenwick RG, Reitz RE, Catanese JJ, Leong DU, Zellner C, Sninsky JJ, Topol EJ, Devlin JJ, Kane JP (Sep 2005). "Identification of Four Gene Variants Associated with Myocardial Infarction". Am J Hum Genet 77 (4): 596–605. doi:10.1086/491674. PMC 1275608. PMID 16175505. 
  4. ^ a b "Entrez Gene: TAS2R50 taste receptor, type 2, member 50". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.