Somatostatin receptor 3

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Somatostatin receptor 3
Symbols SSTR3 ; SS-3-R; SS3-R; SS3R; SSR-28
External IDs OMIM182453 MGI98329 HomoloGene20285 IUPHAR: 357 ChEMBL: 2028 GeneCards: SSTR3 Gene
RNA expression pattern
PBB GE SSTR3 214491 at tn.png
More reference expression data
Species Human Mouse
Entrez 6753 20607
Ensembl ENSG00000278195 ENSMUSG00000044933
UniProt P32745 P30935
RefSeq (mRNA) NM_001051 NM_009218
RefSeq (protein) NP_001042 NP_033244
Location (UCSC) Chr 22:
37.2 – 37.21 Mb
Chr 15:
78.54 – 78.54 Mb
PubMed search [1] [2]

Shekel Somatostatin receptor type 3 is a protein that in humans is encoded by the SSTR3 gene.[1][2]

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.[2]

See also[edit]


  1. ^ Yamada Y, Stoffel M, Espinosa R 3rd, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (Apr 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics 15 (2): 449–452. doi:10.1006/geno.1993.1088. PMID 8449518. 
  2. ^ a b "Entrez Gene: SSTR3 somatostatin receptor 3". 

Further reading[edit]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.