Somatostatin receptor 3

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Somatostatin receptor 3
Identifiers
Symbols SSTR3 ; SS-3-R; SS3-R; SS3R; SSR-28
External IDs OMIM182453 MGI98329 HomoloGene20285 IUPHAR: sst3 ChEMBL: 2028 GeneCards: SSTR3 Gene
RNA expression pattern
PBB GE SSTR3 214491 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 6753 20607
Ensembl ENSG00000278195 ENSMUSG00000044933
UniProt P32745 P30935
RefSeq (mRNA) NM_001051 NM_009218
RefSeq (protein) NP_001042 NP_033244
Location (UCSC) Chr 22:
37.2 – 37.21 Mb
Chr 15:
78.54 – 78.54 Mb
PubMed search [1] [2]

Shekel Somatostatin receptor type 3 is a protein that in humans is encoded by the SSTR3 gene.[1][2]

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.[2]

See also[edit]

References[edit]

  1. ^ Yamada Y, Stoffel M, Espinosa R 3rd, Xiang KS, Seino M, Seino S, Le Beau MM, Bell GI (Apr 1993). "Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms". Genomics 15 (2): 449–452. doi:10.1006/geno.1993.1088. PMID 8449518. 
  2. ^ a b "Entrez Gene: SSTR3 somatostatin receptor 3". 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.