P2RY14

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Purinergic receptor P2Y, G-protein coupled, 14
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols P2RY14 ; BPR105; GPR105; P2Y14
External IDs OMIM610116 MGI2155705 HomoloGene15769 IUPHAR: P2Y14 ChEMBL: 4518 GeneCards: P2RY14 Gene
RNA expression pattern
PBB GE P2RY14 206637 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9934 140795
Ensembl ENSG00000174944 ENSMUSG00000036381
UniProt Q15391 Q9ESG6
RefSeq (mRNA) NM_001081455 NM_001008497
RefSeq (protein) NP_001074924 NP_001008497
Location (UCSC) Chr 3:
150.93 – 151 Mb
Chr 3:
59.11 – 59.13 Mb
PubMed search [1] [2]

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.[1]

The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.[1]

See also[edit]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


External links[edit]

  • "P2Y Receptors: P2Y14". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.