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Econazole

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Econazole
Clinical data
AHFS/Drugs.comMonograph
MedlinePlusa684049
ATC code
Identifiers
  • (RS)-1-{2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.043.932 Edit this at Wikidata
Chemical and physical data
FormulaC18H15Cl3N2O
Molar mass381.683 g/mol g·mol−1
3D model (JSmol)
  • Clc1ccc(c(Cl)c1)C(OCc2ccc(Cl)cc2)Cn3ccnc3
  • InChI=1S/C18H15Cl3N2O/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2 checkY
  • Key:LEZWWPYKPKIXLL-UHFFFAOYSA-N checkY
  (verify)

Econazole nitrate is an antifungal medication of the imidazole class.[1] It is used as a cream under the brand names Spectazole (United States), Ecostatin (Canada), Pevaryl (Western Europe) and Pevisone (the latter consisting of the combination econazole/triamcinolone) to treat skin infections such as athlete's foot, tinea, pityriasis versicolor, ringworm, and jock itch. It is also sold in Canada under the brand name Ecostatin as vaginal ovules to treat vaginal thrush. In Asia, it is sold under the brand name Endix-G (by Dongkwang, Korea), while in Thailand it is sold as Ecosone by Qualimed. In Taiwan, it is sold as Vivicome Cream, manufactured by Yong Chang Pharmeceuticals. In Bangladesh it is sold under the brand name Ecoderm manufactured by Rephco Pharmaceuticals. The combination of Econazole Nitrate with Triamcinolone acetonide is also available under the brand name Ecoderm-TA.[2]



  1. ^ Thienpont, D; Van Cutsem, J; Van Nueten, JM; Niemegeers, CJ; Marsboom, R (1975). "Bilogical and toxicological properties of econazole, a broad-spectrum antimycotic". Arzneimittel-Forschung. 25 (2): 224–30. PMID 1173036.
  2. ^ Template:Http://www.rephco-bd.com/index.php?option=com content&view=article&id=22&Itemid=48