LILRA2
Appearance
Leukocyte immunoglobulin-like receptor subfamily A member 2 (LILRA2, CD85H, ILT1) is a protein that in humans is encoded by the LILRA2 gene.[3][4][5]
Function
LILRA2 senses microbially cleaved immunoglobulin to activate human myeloid cells.[6]
See also
References
- ^ a b c ENSG00000274000, ENSG00000275290, ENSG00000278634 GRCh38: Ensembl release 89: ENSG00000239998, ENSG00000274000, ENSG00000275290, ENSG00000278634 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Samaridis J, Colonna M (Apr 1997). "Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways". Eur J Immunol. 27 (3): 660–5. doi:10.1002/eji.1830270313. PMID 9079806.
- ^ Borges L, Hsu ML, Fanger N, Kubin M, Cosman D (Apr 1998). "A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules". J Immunol. 159 (11): 5192–6. PMID 9548455.
- ^ "Entrez Gene: LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2".
- ^ Hirayasu K, Saito F, Suenaga T, Shida K, Arase N, Oikawa K, Yamaoka T, Murota H, Chibana H, Nagai H, Nakamura Y, Katayama I, Colonna M, Arase H (Apr 2016). "LILRA2 is an innate immune sensor for microbially cleaved immunoglobulins". Nature Microbiology. 1 (6): 16054. doi:10.1038/NMICROBIOL.2016.54.
Further reading
External links
- LILRA2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.