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Tachykinin receptor 2

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Template:PBB Substance-K receptor is a protein that in humans is encoded by the TACR2 gene.[1]

Template:PBB Summary

Selective Ligands

Several selective ligands for NK2 are now available, and although most of the compounds developed so far are peptides, one small-molecule antagonist Saredutant is currently in clinical trials as an anxiolytic and antidepressant.

Agonists

  • GR-64349 - potent and selective agonist, EC50 3.7nM, 7-amino acid polypeptide chain. CAS# 137593-52-3

Antagonists

See also

References

  1. ^ "Entrez Gene: TACR2 tachykinin receptor 2".
  • "Tachykinin Receptors: NK2". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. {{cite web}}: Cite has empty unknown parameter: |coauthors= (help)

Further reading

Template:PBB Further reading

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