TAS2R1

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TAS2R1
Identifiers
Aliases TAS2R1, T2R1, TRB7, taste 2 receptor member 1
External IDs MGI: 2681253 HomoloGene: 10480 GeneCards: 50834
RNA expression pattern
PBB GE TAS2R1 221324 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_019599

NM_020503

RefSeq (protein)

NP_062545.1

NP_065249.2

Location (UCSC) Chr 5: 9.63 – 9.71 Mb Chr 15: 32.18 – 32.18 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Taste receptor type 2 member 1 is a protein that in humans is encoded by the TAS2R1 gene.[1][2][3]

Function[edit]

This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil.[3]

See also[edit]

References[edit]

  1. ^ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (Apr 2000). "A novel family of mammalian taste receptors". Cell 100 (6): 693–702. doi:10.1016/S0092-8674(00)80705-9. PMID 10761934. 
  2. ^ Matsunami H, Montmayeur JP, Buck LB (Apr 2000). "A family of candidate taste receptors in human and mouse". Nature 404 (6778): 601–4. doi:10.1038/35007072. PMID 10766242. 
  3. ^ a b "Entrez Gene: TAS2R1 taste receptor, type 2, member 1". 

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.