S1PR4

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S1PR4
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases S1PR4, EDG6, LPC1, S1P4, SLP4, sphingosine-1-phosphate receptor 4
External IDs MGI: 1333809 HomoloGene: 2799 GeneCards: S1PR4
Targeted by Drug
sphingosine 1-phosphate[1]
RNA expression pattern
PBB GE EDG6 206437 at tn.png

PBB GE EDG6 215859 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003775

NM_010102

RefSeq (protein)

NP_003766.1

NP_034232.1

Location (UCSC) Chr 19: 3.17 – 3.18 Mb Chr 10: 81.5 – 81.5 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Sphingosine-1-phosphate receptor 4 also known as S1PR4 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P4.[4]

Function[edit]

This gene is a member of the endothelial differentiation, G-protein-coupled (EDG) receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue.[4]

See also[edit]

References[edit]

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.