GPR45

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GPR45
Identifiers
AliasesGPR45, PSP24, PSP24(ALPHA), PSP24A, G protein-coupled receptor 45
External IDsMGI: 2135882 HomoloGene: 5228 GeneCards: GPR45
Gene location (Human)
Chromosome 2 (human)
Chr.Chromosome 2 (human)[1]
Chromosome 2 (human)
Genomic location for GPR45
Genomic location for GPR45
Band2q12.1Start105,241,743 bp[1]
End105,243,049 bp[1]
RNA expression pattern
PBB GE GPR45 211175 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007227

NM_053107

RefSeq (protein)

NP_009158

NP_444337

Location (UCSC)Chr 2: 105.24 – 105.24 MbChr 1: 42.95 – 43.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 45 is a protein that in humans is encoded by the GPR45 gene.[5][6]

This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000135973 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041907 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Marchese A, Sawzdargo M, Nguyen T, Cheng R, Heng HH, Nowak T, Im DS, Lynch KR, George SR, O'dowd BF (May 1999). "Discovery of three novel orphan G-protein-coupled receptors". Genomics. 56 (1): 12–21. doi:10.1006/geno.1998.5655. PMID 10036181. 
  6. ^ a b "Entrez Gene: GPR45 G protein-coupled receptor 45". 

Further reading[edit]