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G protein-coupled receptor 1
Symbol GPR1
External IDs OMIM600239 MGI2385324 HomoloGene21094 IUPHAR: 82 GeneCards: GPR1 Gene
RNA expression pattern
PBB GE GPR1 214605 x at tn.png
More reference expression data
Species Human Mouse
Entrez 2825 241070
Ensembl ENSG00000183671 ENSMUSG00000046856
UniProt P46091 Q8K087
RefSeq (mRNA) NM_001098199 NM_146250
RefSeq (protein) NP_001091669 NP_666362
Location (UCSC) Chr 2:
206.18 – 206.22 Mb
Chr 1:
63.18 – 63.21 Mb
PubMed search [1] [2]

G protein-coupled receptor 1, also known as GPR1, is a protein that in humans is encoded by the GPR1 gene.[1][2]

GPR1 is a member of the G protein-coupled receptor family of transmembrane receptors. It functions as a receptor for chemerin. [3] Other receptors for chemerin include CMKLR1 and CCRL2.


  1. ^ "Entrez Gene: GPR1 G protein-coupled receptor 1". 
  2. ^ Marchese A, Docherty JM, Nguyen T, Heiber M, Cheng R, Heng HH, Tsui LC, Shi X, George SR, O'Dowd BF (October 1994). "Cloning of human genes encoding novel G protein-coupled receptors". Genomics 23 (3): 609–18. doi:10.1006/geno.1994.1549. PMID 7851889. 
  3. ^ Barnea G, Strapps W, Herrada G, Berman Y, Ong J, Kloss B, Axel R, Lee KJ (January 2008). "The genetic design of signaling cascades to record receptor activation". Proc. Natl. Acad. Sci. U.S.A. 105 (1): 64–9. doi:10.1073/pnas.0710487105. PMC 2224232. PMID 18165312. 

Further reading[edit]