GPR110

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ADGRF1
Identifiers
Aliases ADGRF1, KPG_012, PGR19, hGPCR36, GPR110, adhesion G protein-coupled receptor F1
External IDs MGI: 1924846 HomoloGene: 124643 GeneCards: 266977
RNA expression pattern
PBB GE GPR110 220907 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_025048
NM_153840

NM_133776

RefSeq (protein)

NP_079324.2
NP_722582.2

NP_598537.2

Location (UCSC) Chr 6: 47 – 47.04 Mb Chr 17: 43.27 – 43.32 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Probable G-protein coupled receptor 110 is a protein that in humans is encoded by the GPR110 gene.[1][2] This gene encodes a member of the adhesion-GPCR receptor family.[3] Family members are characterized by an extended extracellular region with a variable number of N-terminal protein modules coupled to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.[4]

References[edit]

  1. ^ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett 531 (3): 407–14. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584. 
  2. ^ "Entrez Gene: GPR110 G protein-coupled receptor 110". 
  3. ^ Stacey M, Yona S (2011). Adhesion-GPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 1-4419-7912-3. 
  4. ^ Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC 3321182. PMID 22333914. 

Further reading[edit]