GPR133

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ADGRD1
Identifiers
AliasesADGRD1, PGR25, GPR133, adhesion G protein-coupled receptor D1
External IDsMGI: 3041203 HomoloGene: 34616 GeneCards: ADGRD1
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for ADGRD1
Genomic location for ADGRD1
Band12q24.33Start130,953,907 bp[1]
End131,141,469 bp[1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_198827
NM_001330497

NM_001081342
NM_177734
NM_001347486

RefSeq (protein)

NP_001317426
NP_942122

NP_001074811
NP_001334415

Location (UCSC)Chr 12: 130.95 – 131.14 MbChr 5: 129.1 – 129.2 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 133 is a protein that in humans is encoded by the GPR133 gene.[5][6]

This gene encodes a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.[7][8]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000111452 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000044017 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ "Entrez Gene: GPR133 G protein-coupled receptor 133".
  6. ^ Fredriksson R, Lagerstrom MC, Hoglund PJ, Schioth HB (Nov 2002). "Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions". FEBS Lett. 531 (3): 407–14. doi:10.1016/S0014-5793(02)03574-3. PMID 12435584.
  7. ^ Stacey M, Yona S (2011). AdhesionGPCRs: Structure to Function (Advances in Experimental Medicine and Biology). Berlin: Springer. ISBN 1-4419-7912-3.
  8. ^ Araç D, Boucard AA, Bolliger MF, Nguyen J, Soltis SM, Südhof TC, Brunger AT (March 2012). "A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis". EMBO J. 31 (6): 1364–78. doi:10.1038/emboj.2012.26. PMC 3321182. PMID 22333914.

Further reading[edit]