Super Conserved Receptor Expressed in Brain

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G protein-coupled receptor 27
Identifiers
SymbolGPR27
Alt. symbolsSREB1
NCBI gene2850
HGNC4482
OMIM605187
RefSeqNM_018971
UniProtQ9NS67
Other data
LocusChr. 3 p21-p14
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StructuresSwiss-model
DomainsInterPro
G protein-coupled receptor 85
Identifiers
SymbolGPR85
Alt. symbolsSREB2
NCBI gene54329
HGNC4536
OMIM605188
RefSeqNM_018970
UniProtP60893
Other data
LocusChr. 7 q31
Search for
StructuresSwiss-model
DomainsInterPro
G protein-coupled receptor 173
Identifiers
SymbolGPR173
Alt. symbolsSREB3
NCBI gene54328
HGNC18186
OMIM300253
RefSeqNM_018969
UniProtQ9NS66
Other data
LocusChr. X p11
Search for
StructuresSwiss-model
DomainsInterPro

The SREB (Super Conserved Receptor Expressed in Brain) are a group of related G-protein coupled receptors.[1] Since no endogenous ligands have yet been identified for these receptors, they are classified as orphan receptors.

References

  1. ^ Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K (2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem. Biophys. Res. Commun. 272 (2): 576–82. doi:10.1006/bbrc.2000.2829. PMID 10833454.

External links