GPR85

GPR85
Identifiers
Aliases	GPR85, SREB, SREB2, G protein-coupled receptor 85
External IDs	OMIM: 605188; MGI: 1927851; HomoloGene: 10355; GeneCards: GPR85; OMA:GPR85 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	113,087,778 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	13,839,941 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; caudate nucleus; ; primary visual cortex; ; putamen; ; dorsolateral prefrontal cortex; ; ganglionic eminence; ; prefrontal cortex; ; lateral nuclear group of thalamus; ; nucleus accumbens; ; Brodmann area 23;
	Top expressed in
	barrel cortex; ; Rostral migratory stream; ; Region I of hippocampus proper; ; piriform cortex; ; ventromedial nucleus; ; substantia nigra; ; temporal lobe; ; facial motor nucleus; ; lobe of cerebellum; ; habenula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; protein binding; signal transducer activity;
Cellular component	integral component of membrane; endoplasmic reticulum; membrane; plasma membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	54329
	64450
	ENSG00000164604
	ENSMUSG00000048216
	P60893
	P60894
	NM_001146265; NM_001146266; NM_001146267; NM_018970
	NM_145066; NM_001330666; NM_001330667
	NP_001139737; NP_001139738; NP_001139739; NP_061843
	NP_001317595; NP_001317596; NP_659503
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 85 is a protein that in humans is encoded by the GPR85 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000164604 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000048216 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Hellebrand S, Schaller HC, Wittenberger T (Nov 2000). "The brain-specific G-protein coupled receptor GPR85 with identical protein sequence in man and mouse maps to human chromosome 7q31". Biochim Biophys Acta. 1493 (1–2): 269–72. doi:10.1016/s0167-4781(00)00182-2. PMID 10978537.
^ Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K (Jul 2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem Biophys Res Commun. 272 (2): 576–82. doi:10.1006/bbrc.2000.2829. PMID 10833454.
^ "Entrez Gene: GPR85 G protein-coupled receptor 85".

Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Jeon J, Kim C, Sun W, et al. (2002). "Cloning and localization of rgpr85 encoding rat G-protein-coupled receptor". Biochem. Biophys. Res. Commun. 298 (4): 613–8. doi:10.1016/S0006-291X(02)02515-9. PMID 12408996.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Matsumoto M, Beltaifa S, Weickert CS, et al. (2005). "A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain". Brain Res. Mol. Brain Res. 138 (1): 58–69. doi:10.1016/j.molbrainres.2005.04.002. PMID 15893849.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000164604 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000048216 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10978537-5] Hellebrand S, Schaller HC, Wittenberger T (Nov 2000). "The brain-specific G-protein coupled receptor GPR85 with identical protein sequence in man and mouse maps to human chromosome 7q31". Biochim Biophys Acta. 1493 (1–2): 269–72. doi:10.1016/s0167-4781(00)00182-2. PMID 10978537.

[pmid10833454-6] Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K (Jul 2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem Biophys Res Commun. 272 (2): 576–82. doi:10.1006/bbrc.2000.2829. PMID 10833454.

[entrez-7] "Entrez Gene: GPR85 G protein-coupled receptor 85".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

GPR85

See also

References

Further reading