Protein wntless homolog
G protein-coupled receptor 177 (GPR177), commonly known as Wntless, is a human gene[5] that encodes a receptor for Wnt proteins in Wnt-secreting cells.[6]
Wntless was shown to be a cargo for the retromer complex.[6] It has been found essential for hair follicle induction.[7] Template:PBB Summary
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000116729 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028173 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: GPR177 G protein-coupled receptor 177".
- ^ a b Eaton S (January 2008). "Retromer retrieves wntless". Dev. Cell. 14 (1): 4–6. doi:10.1016/j.devcel.2007.12.014. PMID 18194646.
- ^ Fu, J.; Hsu, W. (2012). "Epidermal Wnt Controls Hair Follicle Induction by Orchestrating Dynamic Signaling Crosstalk between the Epidermis and Dermis". Journal of Investigative Dermatology. 133 (4): 890–8. doi:10.1038/jid.2012.407. PMID 23190887.
Further reading
See also
- GPR177+receptor,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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