GPR34

GPR34
Identifiers
Aliases	GPR34, LYPSR1, G protein-coupled receptor 34
External IDs	OMIM: 300241; MGI: 1346334; HomoloGene: 36174; GeneCards: GPR34; OMA:GPR34 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	41,697,275 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	13,507,097 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; smooth muscle tissue; ; testicle; ; placenta; ; mucosa of ileum; ; right coronary artery; ; appendix; ; gallbladder; ; rectum; ; monocyte;
	Top expressed in
	lumbar subsegment of spinal cord; ; stroma of bone marrow; ; dentate gyrus of hippocampal formation granule cell; ; mesenteric lymph nodes; ; Region I of hippocampus proper; ; superior frontal gyrus; ; primary visual cortex; ; spleen; ; ankle; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled purinergic nucleotide receptor activity; G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction; G protein-coupled purinergic nucleotide receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2857
	23890
	ENSG00000171659
	ENSMUSG00000040229
	Q9UPC5
	Q9R1K6
	NM_001033513; NM_001033514; NM_001097579; NM_005300
	NM_011823
	NP_001091048; NP_005291
	NP_035953
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 34 is a protein that in humans is encoded by the GPR34 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000171659 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000040229 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Schoneberg T, Schulz A, Grosse R, Schade R, Henklein P, Schultz G, Gudermann T (Aug 1999). "A novel subgroup of class I G-protein-coupled receptors". Biochim Biophys Acta. 1446 (1–2): 57–70. doi:10.1016/s0167-4781(99)00081-0. PMID 10395919.
^ Marchese A, Sawzdargo M, Nguyen T, Cheng R, Heng HH, Nowak T, Im DS, Lynch KR, George SR, O'dowd BF (May 1999). "Discovery of three novel orphan G-protein-coupled receptors". Genomics. 56 (1): 12–21. doi:10.1006/geno.1998.5655. PMID 10036181.
^ "Entrez Gene: GPR34 G protein-coupled receptor 34".

Liebscher I, Müller U, Teupser D, et al. (2011). "Altered immune response in mice deficient for the G protein-coupled receptor GPR34". J Biol Chem. 286 (3): 2101–10. doi:10.1074/jbc.M110.196659. PMC 3023507. PMID 21097509.{{cite journal}}: CS1 maint: unflagged free DOI (link)
Ritscher L, Engemaier E, Stäubert C, et al. (2012). "The ligand specificity of the G-protein-coupled receptor GPR34". Biochem J. 443 (3): 841–50. doi:10.1042/BJ20112090. PMID 22348703.

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