GPR78

GPR78
Identifiers
Aliases	GPR78, G protein-coupled receptor 78
External IDs	OMIM: 606921; HomoloGene: 50960; GeneCards: GPR78; OMA:GPR78 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	8,619,761 bp
RNA expression pattern
	Top expressed in
	vagina; ; stromal cell of endometrium; ; right uterine tube; ; canal of the cervix; ; gallbladder; ; prefrontal cortex; ; placenta; ; left uterine tube; ; urinary bladder; ; smooth muscle tissue;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; protein binding;
Cellular component	integral component of membrane; plasma membrane; membrane; intracellular anatomical structure;
Biological process	G protein-coupled receptor signaling pathway; adenylate cyclase-activating G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	27201
	n/a
	ENSG00000155269
	n/a
	Q96P69
	n/a
	NM_080819
	n/a
	NP_543009
	n/a
	Wikidata
View/Edit Human

Probable G-protein coupled receptor 78 is a protein that in humans is encoded by the GPR78 gene.^[3]^[4]

G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.[supplied by OMIM]^[4]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000155269 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
^ ^a ^b "Entrez Gene: GPR78 G protein-coupled receptor 78".

van Laar T, Schouten T, Hoogervorst E, et al. (2000). "The novel MMS-inducible gene Mif1/KIAA0025 is a target of the unfolded protein response pathway". FEBS Lett. 469 (1): 123–31. doi:10.1016/S0014-5793(00)01253-9. PMID 10708769. S2CID 6419566.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Underwood SL, Christoforou A, Thomson PA, et al. (2006). "Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia". Mol. Psychiatry. 11 (4): 384–94. doi:10.1038/sj.mp.4001786. PMID 16389273.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000155269 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11574155-3] Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.

[entrez-4] "Entrez Gene: GPR78 G protein-coupled receptor 78".

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[3]

[4]

References

Further reading