GPR21

GPR21
Identifiers
Aliases	GPR21, G protein-coupled receptor 21
External IDs	OMIM: 601909; MGI: 2441890; HomoloGene: 74546; GeneCards: GPR21; OMA:GPR21 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	123,035,665 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	37,410,615 bp
RNA expression pattern
	Top expressed in
	right coronary artery; ; popliteal artery; ; left coronary artery; ; ganglionic eminence; ; prefrontal cortex; ; ascending aorta; ; muscle tissue; ; Brodmann area 9; ; superior frontal gyrus; ; cervix;
	Top expressed in
	ganglionic eminence; ; mesencephalon; ; neural tube; ; morula; ; rhombencephalon; ; olfactory bulb; ; secondary oocyte; ; spermatocyte; ; uterus; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	dopamine neurotransmitter receptor activity, coupled via Gs; signal transducer activity; G protein-coupled receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	negative regulation of insulin receptor signaling pathway; glucose homeostasis; signal transduction; positive regulation of multicellular organism growth; G protein-coupled receptor signaling pathway; dopamine receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2844
	338346
	ENSG00000188394
	ENSMUSG00000053164
	Q99679
	Q8BX79
	NM_005294
	NM_177383
	NP_005285
	NP_796357
	Wikidata
View/Edit Human	View/Edit Mouse

Probable G-protein coupled receptor 21 is a protein that in humans is encoded by the GPR21 gene.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000188394 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000053164 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GPR21 G protein-coupled receptor 21".

O'Dowd BF, Nguyen T, Jung BP, et al. (1997). "Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes". Gene. 187 (1): 75–81. doi:10.1016/S0378-1119(96)00722-6. PMID 9073069.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

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