TAAR8

TAAR8
Identifiers
Aliases	TAAR8, GPR102, TA5, TAR5, TRAR5, TaR-5, TaR-8, trace amine associated receptor 8
External IDs	OMIM: 606927 MGI: 2685995 HomoloGene: 77586 GeneCards: TAAR8
Gene location (Human)
Chr.	Chromosome 6 (human)
End	132,553,721 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	23,968,192 bp
RNA expression pattern
	Top expressed in
	pancreas; ; female reproductive system; ; organ system; ; material anatomical entity; ; kidney; ; renal cortex; ; vagina; ; islet of Langerhans; ; tibial nerve;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	trace-amine receptor activity; G protein-coupled receptor activity; signal transducer activity;
Cellular component	plasma membrane; membrane; integral component of membrane;
Biological process	G protein-coupled receptor signaling pathway; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	83551
	382348
	ENSG00000146385
	ENSMUSG00000100186
	Q969N4
	Q5QD06
	NM_053278
	NM_001010837
	NP_444508
	NP_001010837
	Wikidata
View/Edit Human	View/Edit Mouse

Trace amine-associated receptor 8 is a protein that in humans is encoded by the TAAR8 gene.^[5]^[6]^[7] In humans, TAAR8 is the only trace amine-associated receptor that is known to be G_i/o-coupled.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000146385 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000100186 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lee DK, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans JF, George SR, O'Dowd BF (Sep 2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
^ Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC (Feb 2005). "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors". Genomics. 85 (3): 372–85. doi:10.1016/j.ygeno.2004.11.010. PMID 15718104.
^ "Entrez Gene: TAAR8 trace amine associated receptor 8".
^ Mühlhaus J, Dinter J, Nürnberg D, Rehders M, Depke M, Golchert J, Homuth G, Yi CX, Morin S, Köhrle J, Brix K, Tschöp M, Kleinau G, Biebermann H (2014). "Analysis of human TAAR8 and murine Taar8b mediated signaling pathways and expression profile". Int J Mol Sci. 15 (11): 20638–55. doi:10.3390/ijms151120638. PMC 4264187. PMID 25391046.{{cite journal}}: CS1 maint: unflagged free DOI (link)