TAAR2

TAAR2
Identifiers
Aliases	TAAR2, GPR58, taR-2, trace amine associated receptor 2, trace amine associated receptor 2 (gene/pseudogene)
External IDs	OMIM: 604849; MGI: 2685071; HomoloGene: 110760; GeneCards: TAAR2; OMA:TAAR2 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	132,624,275 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	23,817,481 bp
RNA expression pattern
	Top expressed in
	testicle; ; tibialis anterior muscle; ; gonad; ; deltoid muscle; ; lower lobe of lung; ; left testis; ; right testis;
	Top expressed in
	embryo; ; morula; ; nose; ; nasal septum; ; ganglion; ; Grüneberg ganglion; ; stomach;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity; trace-amine receptor activity;
Cellular component	plasma membrane; membrane; integral component of membrane;
Biological process	signal transduction; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9287
	209512
	ENSG00000146378
	ENSMUSG00000059763
	Q9P1P5
	Q5QD17
	NM_001033080; NM_014626
	NM_001007266
	NP_001028252; NP_055441
	NP_001007267
	Wikidata
View/Edit Human	View/Edit Mouse

Trace amine-associated receptor 2 is a protein that in humans is encoded by the TAAR2 gene.^[5]^[6]^[7]

A recent paper showed that, along with TAAR1, TAAR2 is required for full activity of trace amines in PMN cells.^[8] Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000146378 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000059763 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lee DK, Lynch KR, Nguyen T, Im DS, Cheng R, Saldivia VR, Liu Y, Liu IS, Heng HH, Seeman P, George SR, O'Dowd BF, Marchese A (June 2000). "Cloning and characterization of additional members of the G protein-coupled receptor family". Biochim Biophys Acta. 1490 (3): 311–23. doi:10.1016/s0167-4781(99)00241-9. PMID 10684976.
^ Lindemann L, Ebeling M, Kratochwil NA, Bunzow JR, Grandy DK, Hoener MC (February 2005). "Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors". Genomics. 85 (3): 372–85. doi:10.1016/j.ygeno.2004.11.010. PMID 15718104.
^ "Entrez Gene: TAAR2 trace amine associated receptor 2".
^ Babusyte A, Kotthoff M, Fiedler J, Krautwurst D (March 2013). "Biogenic amines activate blood leukocytes via trace amine-associated receptors TAAR1 and TAAR2". J. Leukoc. Biol. 93 (3): 387–94. doi:10.1189/jlb.0912433. PMID 23315425.