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CD79B

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CD79B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCD79B, AGM6, B29, IGB, CD79b molecule, Igbeta
External IDsOMIM: 147245; MGI: 96431; HomoloGene: 521; GeneCards: CD79B; OMA:CD79B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000626
NM_001039933
NM_021602
NM_001329050

NM_008339
NM_001313939

RefSeq (protein)

NP_000617
NP_001035022
NP_001315979
NP_067613

NP_001300868
NP_032365

Location (UCSC)Chr 17: 63.93 – 63.93 MbChr 11: 106.2 – 106.21 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene.[5]

It is associated with agammaglobulinemia-6.

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.[5]

See also

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References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000007312Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040592Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: CD79B CD79b molecule, immunoglobulin-associated beta".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.