CD83

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CD83 molecule
Identifiers
Symbols CD83 ; BL11; HB15
External IDs OMIM604534 MGI1328316 HomoloGene3121 GeneCards: CD83 Gene
RNA expression pattern
PBB GE CD83 204440 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9308 12522
Ensembl ENSG00000112149 ENSMUSG00000015396
UniProt Q01151 O88324
RefSeq (mRNA) NM_001040280 NM_001289915
RefSeq (protein) NP_001035370 NP_001276844
Location (UCSC) Chr 6:
14.12 – 14.14 Mb
Chr 13:
43.79 – 43.8 Mb
PubMed search [1] [2]

CD83 (Cluster of Differentiation 83) is a human protein encoded by the CD83 gene.[1]

See also[edit]

References[edit]

Further reading[edit]

  • Lechmann M, Berchtold S, Hauber J, Steinkasserer A (2002). "CD83 on dendritic cells: more than just a marker for maturation.". Trends Immunol. 23 (6): 273–5. doi:10.1016/S1471-4906(02)02214-7. PMID 12072358. 
  • Zhou L, Schwarting R, Smith H, Tedder T (1992). "A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily.". J. Immunol. 149 (2): 735–42. PMID 1378080. 
  • Zhou L, Tedder T (1995). "Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily.". J. Immunol. 154 (8): 3821–35. PMID 7706722. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. 
  • Kozlow E, Wilson G, Fox C, Kehrl J (1993). "Subtractive cDNA cloning of a novel member of the Ig gene superfamily expressed at high levels in activated B lymphocytes". Blood 81 (2): 454–61. PMID 8422464. 
  • de la Fuente M, Pizcueta P, Nadal M, Bosch J, Engel P (1997). "CD84 leukocyte antigen is a new member of the Ig superfamily". Blood 90 (6): 2398–405. PMID 9310491. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. 
  • Olavesen M, Bentley E, Mason R, Stephens R, Ragoussis J (1998). "Fine mapping of 39 ESTs on human chromosome 6p23-p25". Genomics 46 (2): 303–6. doi:10.1006/geno.1997.5032. PMID 9417921. 
  • Twist C, Beier D, Disteche C, Edelhoff S, Tedder T (1998). "The mouse Cd83 gene: structure, domain organization, and chromosome localization". Immunogenetics 48 (6): 383–93. doi:10.1007/s002510050449. PMID 9799334. 
  • Berchtold S, Mühl-Zürbes P, Heufler C, Winklehner P, Schuler G, Steinkasserer A (1999). "Cloning, recombinant expression and biochemical characterization of the murine CD83 molecule which is specifically upregulated during dendritic cell maturation". FEBS Lett. 461 (3): 211–6. doi:10.1016/S0014-5793(99)01465-9. PMID 10567699. 
  • Scholler N, Hayden-Ledbetter M, Hellström K, Hellström I, Ledbetter J (2001). "CD83 is a sialic acid-binding Ig-like lectin (Siglec) adhesion receptor that binds monocytes and a subset of activated CD8+ T cells". J. Immunol. 166 (6): 3865–72. doi:10.4049/jimmunol.166.6.3865. PMID 11238630. 
  • Fanales-Belasio E, Moretti S, Nappi F, Barillari G, Micheletti F, Cafaro A et al. (2002). "Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses". J. Immunol. 168 (1): 197–206. doi:10.4049/jimmunol.168.1.197. PMID 11751963. 
  • Berchtold S, Mühl-Zürbes P, Maczek E, Golka A, Schuler G, Steinkasserer A (2003). "Cloning and characterization of the promoter region of the human CD83 gene". Immunobiology 205 (3): 231–46. doi:10.1078/0171-2985-00128. PMID 12182451. 
  • te Velde A, van Kooyk Y, Braat H, Hommes D, Dellemijn T, Slors J et al. (2003). "Increased expression of DC-SIGN+IL-12+IL-18+ and CD83+IL-12-IL-18- dendritic cell populations in the colonic mucosa of patients with Crohn's disease". Eur. J. Immunol. 33 (1): 143–51. doi:10.1002/immu.200390017. PMID 12594843. 
  • Dudziak D, Kieser A, Dirmeier U, Nimmerjahn F, Berchtold S, Steinkasserer A et al. (2003). "Latent Membrane Protein 1 of Epstein-Barr Virus Induces CD83 by the NF-κB Signaling Pathway". J. Virol. 77 (15): 8290–8. doi:10.1128/JVI.77.15.8290-8298.2003. PMC 165234. PMID 12857898. 
  • Hock B, Haring L, Steinkasserer A, Taylor K, Patton W, McKenzie J (2004). "The soluble form of CD83 is present at elevated levels in a number of hematological malignancies". Leuk. Res. 28 (3): 237–41. doi:10.1016/S0145-2126(03)00255-8. PMID 14687618. 
  • Sénéchal B, Boruchov A, Reagan J, Hart D, Young J (2004). "Infection of mature monocyte-derived dendritic cells with human cytomegalovirus inhibits stimulation of T-cell proliferation via the release of soluble CD83". Blood 103 (11): 4207–15. doi:10.1182/blood-2003-12-4350. PMID 14962896. 
  • Cao W, Lee S, Lu J (2005). "CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells". Biochem. J. 385 (Pt 1): 85–93. doi:10.1042/BJ20040741. PMC 1134676. PMID 15320871. 

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