P2RY4

P2RY4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2B6Q
Identifiers
Aliases	P2RY4, NRU, P2P, P2Y4, UNR, pyrimidinergic receptor P2Y4
External IDs	OMIM: 300038; MGI: 1926594; HomoloGene: 20568; GeneCards: P2RY4; OMA:P2RY4 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	70,260,204 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	99,638,475 bp
RNA expression pattern
	Top expressed in
	tibialis anterior muscle; ; mucosa of ileum; ; optic nerve; ; deltoid muscle; ; skin of abdomen; ; rectum; ; skin of limb; ; skin of leg; ; skin of hip; ; transverse colon;
	Top expressed in
	esophagus; ; right ventricle; ; lip; ; tibiofemoral joint; ; digastric muscle; ; gastrula; ; carotid body; ; liver; ; jejunum; ; zone of skin;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled purinergic nucleotide receptor activity; G protein-coupled UTP receptor activity; ATP binding; G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; basolateral plasma membrane; integral component of plasma membrane; apical plasma membrane; membrane; glutamatergic synapse; integral component of presynaptic active zone membrane;
Biological process	positive regulation of cytosolic calcium ion concentration; phospholipase C-activating G protein-coupled receptor signaling pathway; transepithelial chloride transport; signal transduction; G protein-coupled purinergic nucleotide receptor signaling pathway; cellular response to prostaglandin E stimulus; G protein-coupled receptor signaling pathway; cellular response to ATP; regulation of presynaptic cytosolic calcium ion concentration; regulation of synaptic vesicle exocytosis;
	Sources:Amigo / QuickGO
Orthologs
	5030
	57385
	ENSG00000186912
	ENSMUSG00000044359
	P51582
	Q9JJS7
	NM_002565
	NM_020621
	NP_002556
	NP_065646
	Wikidata
View/Edit Human	View/Edit Mouse

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.^[5]^[6]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000186912 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000044359 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Communi D, Pirotton S, Parmentier M, Boeynaems JM (Feb 1996). "Cloning and functional expression of a human uridine nucleotide receptor". J Biol Chem. 270 (52): 30849–52. doi:10.1074/jbc.270.52.30849. PMID 8537336.{{cite journal}}: CS1 maint: unflagged free DOI (link)
^ "Entrez Gene: P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4".

External links

"P2Y Receptors: P2Y₄". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology.

P2RY4

See also

References

External links

Further reading