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Distal-less homeobox 6
Symbols DLX6 ; MGC125282; MGC125283; MGC125284; MGC125285
External IDs OMIM600030 HomoloGene87855 GeneCards: DLX6 Gene
RNA expression pattern
PBB GE DLX6 221289 at tn.png
More reference expression data
Species Human Mouse
Entrez 1750 13396
Ensembl ENSG00000006377 ENSMUSG00000029754
UniProt P56179 P70397
RefSeq (mRNA) NM_005222 NM_010057
RefSeq (protein) NP_005213 NP_034187
Location (UCSC) Chr 7:
96.63 – 96.64 Mb
Chr 6:
6.86 – 6.87 Mb
PubMed search [1] [2]

Homeobox protein DLX-6 is a protein that in humans is encoded by the DLX6 gene.[1][2]

This gene encodes a member of a homeobox transcription factor gene family similar to the Drosophila distal-less gene. This family has at least six members that encode proteins with roles in forebrain and craniofacial development. This gene is in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7.[2]


  1. ^ Simeone A, Acampora D, Pannese M, D'Esposito M, Stornaiuolo A, Gulisano M, Mallamaci A, Kastury K, Druck T, Huebner K, et al. (Apr 1994). "Cloning and characterization of two members of the vertebrate Dlx gene family". Proc Natl Acad Sci U S A 91 (6): 2250–4. doi:10.1073/pnas.91.6.2250. PMC 43348. PMID 7907794. 
  2. ^ a b "Entrez Gene: DLX6 distal-less homeobox 6". 

Further reading[edit]