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General transcription factor IIF, polypeptide 2, 30kDa
Protein GTF2F2 PDB 1bby.png
PDB rendering based on 1bby.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols GTF2F2 ; BTF4; RAP30; TF2F2; TFIIF
External IDs OMIM189969 MGI1915955 HomoloGene37884 GeneCards: GTF2F2 Gene
EC number
Species Human Mouse
Entrez 2963 68705
Ensembl ENSG00000188342 ENSMUSG00000067995
UniProt P13984 Q8R0A0
RefSeq (mRNA) NM_004128 NM_026816
RefSeq (protein) NP_004119 NP_081092
Location (UCSC) Chr 13:
45.69 – 45.86 Mb
Chr 14:
75.9 – 76.01 Mb
PubMed search [1] [2]

General transcription factor IIF subunit 2 is a protein that in humans is encoded by the GTF2F2 gene.[1][2]


GTF2F2 has been shown to interact with POLR2E[3] and HTATSF1.[4]

See also[edit]


  1. ^ Heng HH, Xiao H, Shi XM, Greenblatt J, Tsui LC (May 1994). "Genes encoding general initiation factors for RNA polymerase II transcription are dispersed in the human genome". Hum. Mol. Genet. 3 (1): 61–4. doi:10.1093/hmg/3.1.61. PMID 8162052. 
  2. ^ "Entrez Gene: GTF2F2 general transcription factor IIF, polypeptide 2, 38kDa". 
  3. ^ Wei W, Dorjsuren D, Lin Y, Qin W, Nomura T, Hayashi N et al. (Apr 2001). "Direct interaction between the subunit RAP30 of transcription factor IIF (TFIIF) and RNA polymerase subunit 5, which contributes to the association between TFIIF and RNA polymerase II". J. Biol. Chem. 276 (15): 12266–73. doi:10.1074/jbc.M009634200. PMID 11278533. 
  4. ^ Kim JB, Yamaguchi Y, Wada T, Handa H, Sharp PA (Sep 1999). "Tat-SF1 protein associates with RAP30 and human SPT5 proteins". Mol. Cell. Biol. 19 (9): 5960–8. PMC 84462. PMID 10454543. 

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.