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General transcription factor IIIC, polypeptide 2, beta 110kDa
External IDs OMIM604883 MGI1919002 HomoloGene37490 GeneCards: GTF3C2 Gene
RNA expression pattern
PBB GE GTF3C2 212429 s at tn.png
PBB GE GTF3C2 204366 s at tn.png
PBB GE GTF3C2 210620 s at tn.png
More reference expression data
Species Human Mouse
Entrez 2976 71752
Ensembl ENSG00000115207 ENSMUSG00000029144
UniProt Q8WUA4 Q8BL74
RefSeq (mRNA) NM_001035521 NM_027901
RefSeq (protein) NP_001030598 NP_082177
Location (UCSC) Chr 2:
27.55 – 27.58 Mb
Chr 5:
31.15 – 31.18 Mb
PubMed search [1] [2]

General transcription factor 3C polypeptide 2 is a protein that in humans is encoded by the GTF3C2 gene.[1][2]


GTF3C2 has been shown to interact with GTF3C4[3] and GTF3C5.[4]


  1. ^ Sinn E, Wang Z, Kovelman R, Roeder R (Jun 1995). "Cloning and characterization of a TFIIIC2 subunit (TFIIIC beta) whose presence correlates with activation of RNA polymerase III-mediated transcription by adenovirus E1A expression and serum factors". Genes Dev. 9 (6): 675–85. doi:10.1101/gad.9.6.675. PMID 7729686. 
  2. ^ "Entrez Gene: GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa". 
  3. ^ Hsieh Y, Kundu T, Wang Z, Kovelman R, Roeder R (Nov 1999). "The TFIIIC90 subunit of TFIIIC interacts with multiple components of the RNA polymerase III machinery and contains a histone-specific acetyltransferase activity". Mol. Cell. Biol. 19 (11): 7697–704. PMC 84812. PMID 10523658. 
  4. ^ Hsieh Y, Wang Z, Kovelman R, Roeder R (Jul 1999). "Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III". Mol. Cell. Biol. 19 (7): 4944–52. PMC 84305. PMID 10373544. 

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.